Mesalamine 800 mg : Uses, Dosage & Side Effects
Sep 16, 2025
Living with ulcerative colitis or other forms of inflammatory bowel disease (IBD) can be exhausting—physically, emotionally, and mentally. Flare-ups, abdominal pain, and unpredictable symptoms can interfere with daily life and impact your overall well-being. Fortunately, advanced treatments like mesalamine 800 mg are offering new hope for patients seeking long-term relief.
MESALMILE 800 ER, a high-strength formulation of mesalamine 800 mg, is designed to manage inflammation in the colon effectively. With its extended-release (ER) technology, this tablet ensures that the medication works consistently throughout the day, targeting the source of your symptoms and helping you regain control over your digestive health. Whether you're newly diagnosed or managing a chronic condition, mesalamine 800 mg offers a clinically proven path toward remission and relief.
What Is Mesalamine 800 mg?
Mesalamine 800 mg is an extended-release anti-inflammatory drug used primarily to treat ulcerative colitis and inflammatory bowel disease (IBD). It belongs to a class of drugs known as 5-aminosalicylic acid (5-ASA) derivatives, which are known for reducing inflammation in the colon and rectum.
The MESALMILE 800 ER tablet delivers mesalamine gradually throughout the colon, providing long-lasting relief while requiring fewer daily doses than lower-strength options like 400 mg or 500 mg tablets.
By reducing inflammation, tab mesalamine helps patients:
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Reduce rectal bleeding and diarrhea
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Relieve abdominal pain and cramping
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Maintain remission and prevent flare-ups
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Protect the colon from further damage
Mesalamine Mechanism of Action: How It Works
Understanding the mesalamine mechanism of action can help you feel more confident in your treatment plan. Unlike steroids or immune suppressants, mesalamine tablets work locally in the gastrointestinal (GI) tract.
Here's how:
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Mesalamine 800 mg targets inflamed tissues in the colon and rectum.
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It inhibits the production of inflammatory chemicals like prostaglandins and leukotrienes.
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This action reduces inflammation, allows healing of the colon lining, and helps prevent recurrence of symptoms.
The extended-release (ER) feature of MESALMILE 800 ER ensures slow and targeted delivery, so more of the medication acts directly where it’s needed — with minimal absorption into the bloodstream.
Mesalamine Tablet Uses
Mesalamine tablets like MESALMILE 800 ER are commonly prescribed for:
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Ulcerative colitis (mild to moderate cases)
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Maintenance of remission in UC
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Crohn’s colitis (as advised by a doctor)
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Proctitis and proctosigmoiditis
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Post-surgical inflammation control in some cases
Common Mesalamine Side Effects
While mesalamine is generally well-tolerated, some patients may experience side effects. These are usually mild and temporary.
Common side effects:
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Nausea
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Headache
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Abdominal pain
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Flatulence (gas)
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Mild diarrhea
Rare but serious side effects:
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Kidney issues (rare, especially with long-term use)
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Allergic reactions (rash, itching, swelling)
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Pancreatitis or liver enzyme changes (very rare)
Your doctor may monitor your kidney and liver function during long-term therapy.
Dosage and Administration: How to Take Mesalamine 800 mg
Always take MESALMILE 800 ER exactly as prescribed by your doctor. A typical dosage plan may include:
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Active phase: 2.4 g to 4.8 g/day (3 to 6 tablets/day)
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Maintenance phase: 1.6 g to 2.4 g/day
The tablets should be swallowed whole — do not chew, crush, or break them. You can take mesalamine tablets with or without food, but consistency is key.
Drink plenty of water unless advised otherwise by your doctor.
Why Choose MESALMILE 800 ER by Steris Healthcare?
When selecting a medication for chronic illness, quality, consistency, and clinical reliability matter. Here's why MESALMILE 800 ER stands out:
1. High-Quality Manufacturing Standards
Steris Healthcare adheres to WHO-GMP and ISO-certified processes, ensuring reliable formulations, accurate dosages, and rigorous safety testing.
2. Extended-Release Advantage
The 800 mg strength allows for fewer pills per day, improving compliance. The ER mechanism provides continuous drug action throughout the day.
3. Affordable, Accessible, and Trusted
Steris Healthcare ensures that effective treatment remains affordable, making MESALMILE 800 ER accessible to a wide range of patients.
4. Patient-Centric Approach
MESALMILE 800 ER is designed with ease of swallowing, minimal side effects, and maximum therapeutic benefit — ensuring patient comfort and confidence.
Frequently Asked Questions
1. How long can you take mesalamine?
You can take mesalamine 800 mg long-term — even for several years — especially for maintenance of remission in ulcerative colitis. Regular monitoring (especially kidney function) is recommended to ensure safety during prolonged use.
2. Is mesalamine 800 mg stronger than other doses?
Yes. Mesalamine 800 mg provides a higher concentration per tablet, allowing fewer pills per day and improved compliance for patients needing higher doses.
3. Can mesalamine be taken during pregnancy?
Mesalamine is generally considered safe during pregnancy and breastfeeding, but always consult your doctor before continuing or starting therapy.
4. What should I avoid while taking mesalamine?
Avoid:
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Non-steroidal anti-inflammatory drugs (NSAIDs), unless approved by your doctor
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High-fat or highly processed foods that may irritate your GI tract
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Skipping doses — consistency is critical for remission
Final Thoughts
If you are living with ulcerative colitis or similar inflammatory bowel diseases, mesalamine 800 mg in the MESALMILE 800 ER tablet form offers an effective treatment to manage symptoms and maintain remission. Trusting a quality brand like Steris Healthcare assures you of a safe and consistent supply.
Talk to your healthcare professional today about MESALMILE 800 ER and take the first step toward better gut health. Don't wait for symptoms to worsen—early and continuous treatment is key.
For more information or to start your treatment, contact Steris Healthcare or your local pharmacist.
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