Mesalamine 1200 mg : Mechanism of Action,Uses,Side Effects

Mesalamine 1200 mg is widely used for managing inflammatory bowel diseases like ulcerative colitis, and MESALMILE OD is a trusted brand offering this effective treatment. This mesalamine 1200 mg tablet is formulated as a prolonged-release tablet, providing targeted delivery to the intestines and ensuring sustained symptom relief. If you are looking for a reliable mesalamine tablet to control inflammation and maintain remission, MESALMILE OD by Steris Healthcare can be your ideal choice.

What Is Mesalamine 1200 mg?

Mesalamine 1200 mg is an oral anti-inflammatory drug used to treat ulcerative colitis, proctitis, and sometimes Crohn’s colitis. It belongs to a class of medications called 5-aminosalicylic acids (5-ASA) and works directly in the colon to reduce inflammation and promote healing.

Unlike standard-release tablets, MESALMILE OD is a mesalamine prolonged release tablet, which means:

• It gradually releases the active ingredient along the colon

• You get sustained anti-inflammatory action throughout the day

• It’s taken once daily, which improves patient compliance

The mesalamine 1200 mg dose is ideal for patients who require higher strength medication in fewer tablets, making it more manageable and effective over the long term.

Mesalamine Mechanism of Action: How It Works

The way mesalamine works is simple yet powerful. It does not suppress your immune system like steroids or biologics. Instead, mesalamine 1200 mg:

• Acts locally on the colon lining

• Blocks the production of prostaglandins and leukotrienes, which are inflammatory chemicals

• Reduces swelling, pain, and bleeding

• Helps repair the damaged tissue of the colon

The prolonged-release formulation in MESALMILE OD ensures that mesalamine stays active throughout the large intestine — exactly where the inflammation occurs in ulcerative colitis.

Common Mesalamine Tablet Uses

Mesalamine tablets like MESALMILE OD are prescribed for:

• Induction and maintenance of remission in mild to moderate ulcerative colitis

• Long-term prevention of flare-ups

• Management of proctitis and proctosigmoiditis

• Supportive care in Crohn’s colitis (as per doctor’s advice)

Patients using mesalamine 1200 mg tablets often report:

• Reduced urgency and frequency of bowel movements

• Less abdominal pain and cramping

• Relief from rectal bleeding

• Better quality of life

Common Mesalamine Side Effects

Most people tolerate mesalamine well, but like any medication, some side effects may occur.

Common side effects:

• Headache

• Nausea

• Abdominal pain or cramping

• Diarrhea or flatulence

Rare but serious side effects:

• Kidney function changes (especially with long-term use)

• Allergic reactions (rash, itching, swelling)

• Pancreatitis (rare)

• Liver enzyme abnormalities

To reduce risk, doctors often monitor kidney and liver function during treatment, especially with prolonged use.

Tips for Taking Mesalamine Tablets

• Don’t crush or chew the tablet—this breaks the prolonged-release coating.

• Stick to the prescribed dose and timing every day.

• Drink plenty of fluids, especially during flare-ups.

• Inform your doctor about all medications and supplements you’re taking.

• Attend follow-up appointments for regular blood and urine tests.

Why Choose MESALMILE OD by Steris Healthcare?

MESALMILE OD is a trusted brand developed by Steris Healthcare, known for delivering high-quality, research-backed medications at patient-friendly prices. Here’s why MESALMILE OD stands out:

• Once-daily dosing: Simplifies your routine while maintaining efficacy.

• Prolonged release formulation: Ensures medication is released exactly where and when it’s needed.

• Quality assurance: Manufactured under stringent quality standards.

• Patient-first approach: Backed by Steris Healthcare’s commitment to making advanced treatments accessible.

Choosing MESALMILE OD means you’re not just treating symptoms—you’re supporting your long-term digestive health with a product designed for reliability and convenience.

Frequently Asked Questions

Q: Is mesalamine a steroid?

No, mesalamine is NOT a steroid. It is a non-steroidal anti-inflammatory drug that works locally in the colon. Unlike corticosteroids, mesalamine does not cause significant systemic side effects or immune suppression, making it safer for long-term use.

Q: How long can I take mesalamine 1200 mg?

Mesalamine can be taken long-term, often for years, especially to prevent flare-ups in ulcerative colitis. Regular checkups are recommended to monitor your kidney and liver function, but many patients stay on mesalamine safely for a long time.

Q: Can I stop taking mesalamine when I feel better?

No. Stopping mesalamine suddenly can lead to relapse or worsening of symptoms. Always follow your doctor’s advice and continue medication even during remission, unless advised otherwise.

Q: What should I avoid while taking mesalamine?

Avoid:

• NSAIDs (like ibuprofen), unless your doctor allows them

• Skipping doses

• Crushing or chewing the tablet — it’s meant to be swallowed whole

Conclusion

Managing ulcerative colitis doesn’t have to rule your life. With modern treatments like mesalamine 1200 mg, you can find lasting relief, maintain remission, and get back to enjoying daily life without constant interruption.

MESALMILE OD, developed by Steris Healthcare, offers a powerful, once-daily solution for managing inflammation safely and effectively. Whether you’re just starting treatment or looking for a more convenient long-term option, mesalamine prolonged release tablets could be the solution you’ve been waiting for.