Unlocking the Benefits of Perindopril and Indapamide for Hypertension Management

Feb 29, 2024

Introduction:

PERINDPRIM PLUS is a combination of Perindopril and Indapamide, specially formulated to manage high blood pressure (hypertension) and reduce cardiovascular risks.
This dual-therapy approach provides both vasodilation and diuretic effects, offering effective and comprehensive blood pressure control.

Composition:

  • Perindopril: An ACE (Angiotensin-Converting Enzyme) inhibitor

  • Indapamide: A thiazide-like diuretic

Mechanism of Action:

  • Perindopril works by inhibiting ACE, leading to vasodilation (widening of blood vessels), which lowers blood pressure and improves blood flow.

  • Indapamide acts by promoting the removal of excess salt and water through urine (mild diuretic effect), which further helps to reduce blood pressure.

Together, they offer a synergistic effect for better hypertension management and protection of heart, brain, and kidneys.

Key Benefits:

  • Effective dual-action blood pressure control
  • Reduces the risk of heart attack, stroke, and kidney damage
  • Helps in treating heart failure in some cases
  • Convenient once-daily dosing improves patient compliance
  • Protective effect on blood vessels and organs

Indications / Uses:

  • Treatment of essential hypertension (primary high blood pressure)

  • Management of stable coronary artery disease (in specific cases)

  • Adjunct therapy in heart failure (under specialist supervision)

Dosage (General Guidelines):

  • Typical Dose: One tablet daily, preferably in the morning, as prescribed by the doctor.

  • Adjustment: Dose may vary depending on patient's response, kidney function, and blood pressure levels.

Important: Always take PERINDPRIM PLUS exactly as directed by your healthcare provider.

Administration Advice:

  • Take the tablet once daily, ideally at the same time each day.

  • Can be taken with or without food.

  • Do not stop medication suddenly without consulting your doctor.

Precautions and Warnings:

  • Regular monitoring of blood pressure, electrolytes, and kidney function is advised.

  • Caution in patients with severe kidney disease, liver impairment, or electrolyte imbalances.

  • Avoid in pregnancy and breastfeeding.

  • Inform your doctor about any allergies, especially to ACE inhibitors or sulfonamides.

  • Limit salt substitutes or potassium supplements unless prescribed.

Possible Side Effects:

  • Dizziness or lightheadedness

  • Cough (due to Perindopril)

  • Increased urination (due to Indapamide)

  • Fatigue

  • Low blood pressure (hypotension)

  • Electrolyte imbalance (low potassium or sodium)

Seek immediate medical help if you experience swelling of face/lips, difficulty breathing, or severe dizziness.

Storage Instructions:

  • Store at room temperature (below 25°C).

  • Keep in original packaging to protect from moisture.

  • Keep out of reach of children.

Frequently Asked Questions (FAQs):

Q1. What is PERINDPRIM PLUS used for?
It is used to treat high blood pressure and reduce the risk of serious cardiovascular events like heart attacks and strokes.

Q2. Can PERINDPRIM PLUS be taken at night?
It is usually recommended to be taken in the morning to avoid nighttime urination, but follow your doctor's advice.

Q3. Will PERINDPRIM PLUS cure my blood pressure permanently?
It controls blood pressure but does not cure hypertension; lifelong treatment is often necessary.

Q4. Can I drink alcohol while on PERINDPRIM PLUS?
Limit alcohol intake, as it may further lower your blood pressure and increase dizziness.

Q5. What should I do if I miss a dose?
Take it as soon as you remember. If it’s close to the next dose, skip the missed one. Do not double the dose.

Conclusion:

PERINDPRIM PLUS offers a powerful and synergistic solution for the effective management of high blood pressure and prevention of cardiovascular complications.
By combining the vasodilating effect of Perindopril and the gentle diuretic action of Indapamide, this medication supports better heart health, kidney protection, and overall wellness.
Trust PERINDPRIM PLUS for consistent, reliable, and advanced hypertension control.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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