PERINDPRIM PLUS

PERINDPRIM PLUS is a prescription tablet containing two active ingredients:

1. Perindopril erbumine, an ACE (angiotensin-converting enzyme) inhibitor. It relaxes and widens blood vessels so blood flows more easily and the heart doesn't have to work as hard.
2. Indapamide, a thiazide-like diuretic ("water tablet"). It helps the body remove excess salt and water through urine, which lowers the volume of fluid in blood vessels and reduces pressure.

The two medicines work in complementary ways. Perindopril acts on the hormone system that tightens blood vessels, while indapamide reduces fluid load. Together, they usually lower blood pressure more effectively than either medicine alone.

It is marketed in India by Steris Healthcare Pvt. Ltd. and comes as a tablet. The pack described here contains 10 tablets.

Product Information 

Why Is PERINDPRIM PLUS Important?

1. It tackles hypertension from two angles: Many patients need combination therapy to reach their target blood pressure. Combining an ACE inhibitor with a diuretic is a long-used, evidence-backed approach in hypertension management.

2. It protects long-term health: The goal of treating high blood pressure isn't just a better reading. It's reducing the chance of stroke, heart attack, heart failure and kidney damage over the years. Consistent control is what delivers that protection.

3. It simplifies daily treatment: Taking one tablet instead of two separate medicines reduces the number of pills and makes it easier to stay consistent. Better adherence usually means better control.

4. It suits long-term therapy: Hypertension typically needs lifelong management. A well-tolerated, once-daily combination can fit easily into a daily routine.

Key Benefits 

• Effective blood pressure reduction: The two ingredients work together for a stronger effect than a single agent in many patients.
• Once-daily convenience: Typically prescribed as a single tablet taken once a day, preferably in the morning, so you can build an easy habit.
• Reduced pill burden: A fixed-dose combination means fewer tablets to remember.
• Reduced strain on the heart: Relaxed blood vessels and lower fluid load mean the heart pumps against less resistance.
• Kidney and cardiovascular relevance: ACE inhibitors are widely used in patients with additional cardiovascular or kidney considerations, under medical supervision.
• Reduced swelling from fluid retention: The diuretic component can help with fluid balance.
• Well-established medicines: Both ingredients have been used for many years in clinical practice.

Precautions: What You Should Know Before Using It

Tell your doctor about your full medical history before starting this medicine. Mention it especially if any of the following apply.

Do not use if

• You are pregnant or planning pregnancy. ACE inhibitors can harm a developing baby, particularly in the second and third trimesters.
• You have had angioedema (swelling of the face, lips, tongue or throat), whether from an ACE inhibitor, hereditary, or unknown cause.
• You are allergic to perindopril, indapamide, sulfonamide-derived medicines or any ingredient in the tablet.
• You have severe kidney disease or are on dialysis (as advised by your doctor).
• You have severe liver disease or hepatic encephalopathy.
• You have very low potassium levels.
• You are taking or have recently taken sacubitril/valsartan (a heart failure medicine). A gap of at least 36 hours is generally required.
• You have diabetes or kidney problems and are taking aliskiren.

Use with caution and medical supervision if

• You have kidney problems, liver problems, gout, diabetes or lupus.
• You are dehydrated or have severe vomiting or diarrhoea, which can lower blood pressure too much and affect kidney function.
• You are on a low-salt diet or use potassium supplements or salt substitutes.
• You are elderly, as you may be more sensitive to dizziness and electrolyte changes.
• You are going for surgery or anaesthesia. Inform your surgeon and anaesthetist.
• You are breastfeeding. This medicine is generally not recommended without medical advice.

Possible Side Effects

Like all medicines, PERINDPRIM PLUS can cause side effects, though not everyone experiences them.

Common or mild side effects

• Dry, persistent cough (typical of ACE inhibitors)
• Dizziness or light-headedness
• Headache
• Tiredness or weakness
• Muscle cramps
• Tingling or "pins and needles"
• Changes in taste
• Mild skin rash or itching
• Digestive upset such as nausea, constipation or stomach discomfort
• Vision changes or ringing in the ears (less common)

Less common but important effects

• Low blood pressure, with fainting or severe dizziness
• Low sodium or potassium levels, which can cause confusion, weakness, cramps or irregular heartbeat
• High uric acid, which may trigger gout in susceptible people
• Changes in blood sugar levels

Frequently Asked Questions

Where can I buy Perindopril Erbumine and Indapamide Tablets online?

Perindopril Erbumine and Indapamide Tablets can be purchased through licensed and authorized pharmacies or online medicine platforms, subject to prescription requirements and product availability.

What is the price of Perindopril Erbumine and Indapamide Tablets?

The price may vary depending on the brand, strength, pack size, manufacturer, pharmacy, and applicable offers. Check the current listed price before ordering.

Can I order Perindopril Erbumine and Indapamide Tablets online?

Yes, these tablets may be ordered online through authorized pharmacies when the required prescription and applicable purchasing requirements are fulfilled.

Is Perindopril Erbumine and Indapamide Tablets available from Steris Healthcare?

Availability depends on the current Steris Healthcare product range and stock. Check the relevant product listing or contact Steris Healthcare for current availability.

What is Perindopril Erbumine and Indapamide Tablets used for?

This combination is prescribed for the management of high blood pressure (hypertension). Perindopril is an ACE inhibitor, while indapamide is a diuretic that helps reduce blood pressure through complementary mechanisms.

What is the composition of Perindopril Erbumine and Indapamide Tablets?

The active ingredients are Perindopril Erbumine and Indapamide. The exact strength of each ingredient depends on the specific product formulation and should be checked on the product packaging.

Is a prescription required?

Yes, this combination is generally a prescription medicine and should be used under the supervision of a qualified healthcare professional.

How should Perindopril Erbumine and Indapamide Tablets be taken?

Take the tablets exactly as prescribed by your doctor. They are generally taken orally with water, preferably at the same time each day. Do not change the dose or stop treatment without medical advice.

What should I know before buying Perindopril Erbumine and Indapamide Tablets?

Check the strength, formulation, pack size, manufacturer, expiry date, and authenticity before purchasing. Tell your doctor about kidney or liver problems, low blood pressure, electrolyte abnormalities, pregnancy, or other medicines and supplements you are taking.

How can I order Perindopril Erbumine and Indapamide Tablets online?

Choose a licensed online pharmacy, verify the product details and current price, provide a valid prescription when required, and complete the pharmacy's ordering and payment process. Use the medicine only according to your doctor's directions.