Trelagliptin 100 mg: Uses, Dosage, Side Effects & Weekly Diabetes Control

Introduction

Trelagliptin is a once-weekly oral antidiabetic medication used primarily for the management of type 2 diabetes mellitus. It belongs to the class of drugs known as DPP-4 inhibitors (Dipeptidyl Peptidase-4 inhibitors). By enhancing the levels of incretin hormones, Trelagliptin improves glycemic control in adults with type 2 diabetes.One of the marketed formulations of this drug is TRELAQWK 100, which contains Trelagliptin 100 mg as its active ingredient.

Composition

TRELAQWK 100 contains:

• Active Ingredient: Trelagliptin Succinate equivalent to Trelagliptin 100 mg

• Dosage Form: Oral tablet

• Route of Administration: Oral

• Packaging: Commonly available in blister packs

Uses of Trelagliptin

Trelagliptin is primarily indicated for:

• Type 2 Diabetes Mellitus: Used as monotherapy or in combination with other antidiabetic agents such as metformin, sulfonylureas, or insulin.

• Glycemic Control: Helps in reducing fasting and postprandial blood glucose levels.

It is not indicated for type 1 diabetes mellitus or diabetic ketoacidosis.

Mechanism of Action

Trelagliptin works by:

• Inhibiting the enzyme DPP-4, which increases the levels of active incretin hormones (GLP-1 and GIP).

• These hormones help in:

  • Increasing insulin secretion in response to meals

  • Decreasing glucagon release

  • Improving pancreatic beta-cell function

  • Slowing gastric emptying

Dosage and Administration

Recommended Dose

• 100 mg once weekly (oral administration)

Trelagliptin can be taken with or without food, but should be taken on the same day each week to maintain consistent blood levels.

Dosage Adjustments

• Renal Impairment: Dose adjustment may be needed in moderate-to-severe renal impairment.

• Hepatic Impairment: Use with caution; consult a physician.

Side Effects of Trelagliptin

While Trelagliptin is generally well tolerated, some potential side effects include:

Common Side Effects

• Headache

• Nasopharyngitis

• Upper respiratory tract infections

• Gastrointestinal discomfort

Less Common but Serious Side Effects

• Hypoglycemia (especially when combined with sulfonylureas or insulin)

• Pancreatitis (rare)

• Allergic reactions including rash or itching

• Elevated liver enzymes

Precautions

• Monitor blood glucose levels regularly.

• Use with caution in patients with a history of pancreatitis.

• Periodic liver function and renal function tests are advised.

Advantages of TRELAQWK 100 (Trelagliptin 100 mg)

• Once-weekly dosing: Improves patient adherence compared to daily antidiabetic medications.

• Convenient oral administration

• Low risk of hypoglycemia when used as monotherapy

• Suitable for combination therapy

Contraindications

Trelagliptin is contraindicated in:

• Patients with a known hypersensitivity to Trelagliptin or any of its components

• Patients with type 1 diabetes mellitus

• Individuals with diabetic ketoacidosis

Drug Interactions

• May have additive effects with other antidiabetic medications

• Use caution with drugs that affect renal function or metabolism

• Always inform your healthcare provider about all medications you are taking

FAQs about Trelagliptin 100 mg (TRELAQWK 100)

Q1. What is TRELAQWK 100 used for?

TRELAQWK 100 is used to manage type 2 diabetes mellitus in adults. It helps improve blood sugar control when used alone or in combination with other antidiabetic medications such as metformin or insulin.

Q2. How does Trelagliptin work?

Trelagliptin is a DPP-4 inhibitor that works by increasing the levels of incretin hormones (GLP-1 and GIP). These hormones stimulate insulin release, decrease glucagon levels, and help lower blood glucose levels.

Q3. What is the recommended dose of Trelagliptin?

The usual Trelagliptin dose is 100 mg taken once a week. It should be taken on the same day each week for optimal blood glucose control. Always follow your doctor’s prescribed dosage.

Q4. Can TRELAQWK 100 be taken with other diabetes medications?

Yes, TRELAQWK 100 (Trelagliptin tablet) can be used alone or in combination with other antidiabetic agents such as metformin, sulfonylureas, or insulin. Your doctor will adjust the combination based on your specific needs.

Q5. Are there any side effects of Trelagliptin?

Yes, Trelagliptin side effects may include:

• Headache

• Sore throat

• Nasal congestion

• Stomach upset
  In rare cases, it may cause pancreatitis or allergic reactions. Inform your doctor if you notice any unusual symptoms.

Q6. Is Trelagliptin safe for long-term use?

Clinical studies have shown that Trelagliptin 100 mg is generally well-tolerated for long-term use in patients with type 2 diabetes. Regular monitoring of blood sugar, liver, and kidney function is recommended during prolonged therapy.

Q7. Can I buy Trelagliptin 100 mg online?

Yes, TRELAQWK 100 (Trelagliptin 100 mg) is available through trusted sources like Sterisonline, the official e-commerce platform by Steris Healthcare, one of India's trusted pharmaceutical brands.

Conclusion

TRELAQWK 100, containing Trelagliptin 100 mg, is a novel, once-weekly DPP-4 inhibitor that offers an effective and convenient option for managing type 2 diabetes mellitus. With a favorable safety profile and once-weekly dosing, it enhances patient compliance and glycemic control. However, like all medications, it should be taken under the guidance of a qualified healthcare professional, with regular monitoring for potential side effects and interactions.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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