Naproxen (250mg), Domperidone SR(30mg)

Pain, inflammation, and associated gastric discomfort are common health challenges that significantly affect quality of life. From migraine attacks and joint pain to musculoskeletal injuries and menstrual cramps, effective pain management requires a balanced approach that offers relief without compromising gastrointestinal safety. NAPROXZEN D 250 is a well-formulated combination medicine containing Naproxen 250 mg and Domperidone SR 30 mg, developed to address both pain and related digestive discomfort effectively.

NAPROXZEN D 250 is widely prescribed by healthcare professionals across India for patients who need strong, long-lasting pain relief along with protection against nausea, vomiting, and acidity commonly linked with painkillers. This detailed blog explains NAPROXZEN D 250 uses, benefits, mechanism of action, dosage, side effects, precautions, interactions, and safety profile, making it a reliable informational resource for patients, caregivers, and clinicians.

Composition of NAPROXZEN D 250

Each tablet of NAPROXZEN D 250 contains:

• Naproxen – 250 mg

• Domperidone SR – 30 mg

This dual-drug formulation ensures effective pain control while improving gastrointestinal tolerance and patient compliance.

Understanding Naproxen and Domperidone

Naproxen 250 mg – Anti-inflammatory and Analgesic Action

Naproxen belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs). It works by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, thereby reducing the production of prostaglandins responsible for pain, inflammation, swelling, and fever.

Key properties of Naproxen:

• Strong anti-inflammatory effect

• Long duration of action

• Effective for both acute and chronic pain

• Commonly used in arthritis and migraine management

Domperidone SR 30 mg – Gastrointestinal Protection

Domperidone is a dopamine receptor antagonist with antiemetic and prokinetic properties. It enhances gastric motility and prevents nausea and vomiting. The sustained-release (SR) formulation provides prolonged relief throughout the day.

Key properties of Domperidone:

• Reduces nausea and vomiting

• Improves gastric emptying

• Minimizes NSAID-induced gastric discomfort

• Enhances patient adherence to pain therapy

Uses of NAPROXZEN D 250 Tablet

NAPROXZEN D 250 is prescribed for a wide range of painful and inflammatory conditions, especially when pain is accompanied by gastric symptoms.

1. Migraine and Severe Headache

NAPROXZEN D 250 is commonly used in migraine management. Naproxen reduces inflammation of blood vessels, while Domperidone controls nausea and vomiting, which are frequent migraine-associated symptoms.

2. Musculoskeletal Pain

Effective for pain related to:

• Muscle strain

• Ligament sprains

• Sports injuries

• Back pain

• Neck pain

3. Joint Disorders and Arthritis

NAPROXZEN D 250 is useful in chronic inflammatory conditions such as:

• Osteoarthritis

• Rheumatoid arthritis

• Ankylosing spondylitis

It helps reduce joint stiffness, swelling, and pain, improving mobility.

4. Dental Pain and Post-operative Pain

Provides sustained relief from:

• Toothache

• Post-dental extraction pain

• Minor surgical pain

5. Menstrual Pain (Dysmenorrhea)

Naproxen effectively relieves uterine muscle contractions, while Domperidone reduces nausea and bloating during menstruation.

6. Acute Inflammatory Conditions

Used in:

• Tendinitis

• Bursitis

• Soft tissue injuries

Benefits of NAPROXZEN D 250

NAPROXZEN D 250 offers multiple clinical and practical advantages:

• Powerful and long-lasting pain relief

• Effective reduction of inflammation and swelling

• Prevention of nausea and vomiting

• Improved gastric tolerance

• Sustained-release action for prolonged effect

• Better patient compliance

• Suitable for acute and chronic pain management

This balanced formulation makes it a preferred choice among doctors for patients with sensitive stomachs.

How NAPROXZEN D 250 Works

NAPROXZEN D 250 provides relief through a complementary mechanism of action:

• Naproxen blocks COX enzymes, reducing prostaglandin synthesis and thereby decreasing pain, inflammation, and swelling.

• Domperidone SR enhances gastrointestinal motility and blocks dopamine receptors responsible for nausea and vomiting.

Together, they ensure effective pain relief with improved digestive comfort.

Dosage and Administration of NAPROXZEN D 250

Recommended Dosage

• Dosage should be strictly followed as prescribed by the physician

• Typically taken once or twice daily

• Best taken after meals to minimize gastric irritation

Administration Instructions

• Swallow the tablet whole with water

• Do not crush, break, or chew the tablet

• Maintain a fixed dosing schedule for best results

Dosage adjustments may be required based on patient condition, age, and response to treatment.

Side Effects of NAPROXZEN D 250

Most patients tolerate NAPROXZEN D 250 well when taken as directed. However, some side effects may occur.

Common Side Effects

• Acidity or heartburn

• Nausea

• Dizziness

• Stomach discomfort

• Dry mouth

Less Common Side Effects

• Constipation or diarrhea

• Fatigue

• Mild increase in blood pressure

Rare but Serious Side Effects

• Gastric ulcer or gastrointestinal bleeding

• Allergic reactions (rash, itching, swelling)

• Kidney or liver function impairment

• Irregular heartbeat (domperidone-related, rare)

Immediate medical attention is required if serious side effects occur.

Precautions and Warnings

Before starting NAPROXZEN D 250, inform your doctor if you have:

• History of stomach ulcers or bleeding

• Heart disease or hypertension

• Kidney or liver disorders

• Asthma triggered by NSAIDs

• Electrolyte imbalance

Important Safety Advice

• Avoid alcohol consumption

• Do not exceed the prescribed dose

• Long-term use requires regular medical monitoring

• Not recommended for self-medication

Drug Interactions

NAPROXZEN D 250 may interact with:

• Blood thinners

• Other NSAIDs or painkillers

• Antihypertensive medicines

• Certain antibiotics and antifungals

• Medicines affecting heart rhythm

Always disclose your complete medication history to your doctor.

Use in Special Populations

Elderly Patients

Elderly patients may require careful monitoring due to increased risk of gastrointestinal and cardiovascular side effects.

Pregnancy and Breastfeeding

NAPROXZEN D 250 should be used only if clearly indicated and prescribed by a healthcare professional.

Kidney and Liver Disease

Dose adjustments and regular function tests may be necessary.

Why Choose NAPROXZEN D 250 from Steris Healthcare?

Steris Healthcare is committed to delivering high-quality, safe, and effective pharmaceutical products. NAPROXZEN D 250 is manufactured under strict quality control standards to ensure reliability and therapeutic consistency.

Key Highlights

• Balanced formulation of Naproxen 250 mg and Domperidone SR 30 mg

• Designed for effective pain relief with gastric comfort

• Trusted by doctors across India

• Suitable for hospital and outpatient use

• Manufactured following international quality guidelines

Storage Instructions

• Store at room temperature

• Protect from heat, moisture, and direct sunlight

• Keep out of reach of children

• Do not use after the expiry date

Conclusion

NAPROXZEN D 250 Tablet, containing Naproxen 250 mg and Domperidone SR 30 mg, is a clinically effective and well-tolerated solution for managing pain and inflammation associated with various acute and chronic conditions. Its dual-action formula ensures strong analgesic and anti-inflammatory effects while minimizing gastric discomfort and nausea.

Frequently Asked Questions 

Can NAPROXZEN D 250 be used for migraine attacks?

Yes, it is commonly prescribed for migraine pain with nausea.

Is NAPROXZEN D 250 suitable for daily use?

It should be used for the shortest duration necessary under medical supervision.

Does NAPROXZEN D 250 cause stomach problems?

Domperidone reduces gastric discomfort, but caution is advised with prolonged use.

Can this medicine be taken on an empty stomach?

It is better taken after meals to minimize gastric irritation.

If You Want To Purchase The Product Click Here.

We Have Our Neurology Range.