Mesalamine Delayed Release

Nov 07, 2022

Mesalmile 

Managing inflammatory bowel diseases like ulcerative colitis and Crohn’s disease requires effective treatment to reduce inflammation and maintain remission. Mesalamine 400 mg, branded as MESALMILE 400, is a highly trusted medicine for this purpose. This article provides a detailed guide about mesalamine tablets, including mesalamine uses, mesalamine tablet uses, dosage, mesalamine mechanism of action, side effects, and why Steris Healthcare is the preferred choice for patients.

What is Mesalamine 400 mg?

Mesalamine 400 mg is an anti-inflammatory medicine that works locally in the intestines to control inflammation without affecting the entire body. Mesalamine tablets are designed to release the active ingredient in the colon, which makes them highly effective in managing ulcerative colitis and mild Crohn’s disease.

Doctors prescribe mesalamine tablet uses mainly for:

  • Ulcerative colitis

  • Mild to moderate Crohn’s disease

  • Maintenance therapy to prevent relapses

Starting treatment with mesalamine 400 mg helps patients achieve symptom relief quickly, including reduced diarrhea, abdominal pain, and rectal bleeding.

Mesalamine Uses

Mesalamine is prescribed for several important conditions:

1. Ulcerative Colitis Treatment

Mesalamine tablets are primarily used to treat ulcerative colitis, reducing inflammation in the colon and alleviating symptoms such as diarrhea, blood in stools, and abdominal discomfort.

2. Crohn’s Disease Management

For patients with mild to moderate Crohn’s disease, mesalamine 400 mg helps manage flare-ups by targeting inflammation in the intestines.

3. Maintenance Therapy

After achieving remission, mesalamine tablets can be used long-term to maintain intestinal health and prevent relapses.

4. Localized Anti-Inflammatory Action

The mesalamine mechanism of action involves blocking inflammatory chemicals in the gut lining. This reduces swelling, promotes healing, and minimizes the need for systemic medications with broader side effects.

How Mesalamine 400 mg Works

Mesalamine 400 mg works by acting directly on the colon lining to inhibit inflammatory mediators. The mesalamine mechanism of action ensures:

  • Reduction in bowel inflammation

  • Faster healing of the intestinal lining

  • Prevention of disease flare-ups

  • Better overall digestive health

This targeted action makes mesalamine tablets highly effective and well-tolerated for long-term therapy.

Dosage and How to Take Mesalamine Tablets

The mesalamine dosage for adults depends on the condition and severity:

  • Induction therapy: 800–1600 mg, 2–3 times daily

  • Maintenance therapy: 400–800 mg, 2–3 times daily

Tips for taking MESALMILE 400:

  • Take mesalamine tablets with or without food consistently

  • Swallow whole; do not crush or chew extended-release tablets

  • Stay hydrated and follow a balanced diet

  • Never adjust the mesalamine 400 mg dose without a doctor’s advice

Mesalamine Side Effects

Like all medicines, mesalamine tablets may cause side effects. Most are mild, but some require medical attention:

Common side effects:

  • Mild nausea or vomiting

  • Stomach cramps or discomfort

  • Headache

  • Diarrhea

Serious but rare side effects:

  • Kidney problems (changes in urination, fatigue, swelling)

  • Liver issues (yellowing of eyes/skin, dark urine)

  • Severe allergic reactions

Patients should contact their doctor if they notice unusual symptoms such as persistent vomiting, abdominal pain, or blood in urine.

Precautions Before Using Mesalamine 400 mg

  • Inform your doctor about kidney or liver problems

  • Pregnant or breastfeeding women should consult their doctor

  • Long-term use requires regular kidney function tests

  • Avoid combining with NSAIDs unless advised

Patient’s Point of View

Many patients taking mesalamine 400 mg report improvement in bowel habits, reduced bleeding, and less abdominal discomfort. Regular intake, a balanced diet, and hydration help maintain remission and prevent relapses, improving quality of life.

Why Choose Steris Healthcare’s MESALMILE 400

Quality and reliability are crucial for chronic conditions. Steris Healthcare ensures MESALMILE 400 (Mesalamine 400 mg) is manufactured under strict WHO-GMP standards, offering:

  • High-quality, effective medicine

  • Affordable pricing for long-term therapy

  • Nationwide availability with timely delivery

  • Trusted by doctors and patients across India

Patients can rely on Steris Healthcare for genuine, safe, and effective mesalamine tablets.

Frequently Asked Questions 

1. What is the maximum dosage of mesalamine?
The maximum dosage depends on the condition but can go up to 4.8 grams per day under medical supervision.

2. How long can you take mesalamine?
Patients may use mesalamine tablets long-term for maintenance, sometimes for years, under doctor supervision.

3. Can mesalamine cause kidney problems?
Rarely, mesalamine 400 mg may affect kidney function; regular monitoring is recommended for long-term use.

4. How should mesalamine tablets be taken?
Swallow whole with water. Do not crush or chew extended-release forms.

5. Can I stop mesalamine once symptoms improve?
No, stopping without medical guidance may trigger relapse. Always follow your doctor’s advice.

Conclusion

Mesalamine 400 mg is a reliable and effective option for managing inflammatory bowel conditions like ulcerative colitis and Crohn’s disease. With Steris Healthcare’s high-quality standards, patients can trust they are receiving safe, effective mesalamine tablets for long-term intestinal health.

Consult your doctor today and take mesalamine 400 mg as prescribed for better symptom control, reduced inflammation, and improved quality of life.

Choose Steris Healthcare – your trusted partner in genuine, effective medicines.

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