Gliclazide SR + Metformin SR

GLICLAGLAZE MET is an oral anti-diabetic medication that combines two active ingredients: Gliclazide SR (60 mg) and Metformin SR (500 mg). It is used primarily in the management of type 2 diabetes mellitus. This combination helps control blood sugar levels by targeting multiple mechanisms involved in glucose regulation. Gliclazide belongs to the class of sulfonylureas, while Metformin is a biguanide, both of which complement each other to enhance the therapeutic effect in patients with type 2 diabetes.

Diabetes management is crucial in preventing complications such as neuropathy, nephropathy, and cardiovascular diseases. GLICLAGLAZE MET offers a powerful solution for patients who struggle to achieve target blood sugar levels with diet and exercise alone.

Benefits of GLICLAGLAZE MET

1. Improved Glycemic Control: The combination of Gliclazide and Metformin works synergistically to lower blood sugar levels, making it easier for patients to maintain control over their glucose.
2. Prevention of Complications: Regular use helps prevent the long-term complications of diabetes, such as kidney failure, nerve damage, and eye issues.
3. Enhanced Insulin Sensitivity: Metformin increases insulin sensitivity, making cells more responsive to insulin, while Gliclazide increases the pancreas’s ability to produce insulin.
4. Weight Neutrality: Metformin helps in managing weight by reducing excess fat accumulation, which is often a concern in type 2 diabetes patients.
5. Reduced Risk of Hypoglycemia: The sustained-release formulations minimize the risk of blood sugar dropping too low, offering a balanced control over glucose throughout the day.

Key Features and Ingredients of GLICLAGLAZE MET

• Gliclazide SR (60 mg): This is a sulfonylurea that stimulates the pancreas to release more insulin. It helps to lower blood sugar levels by enhancing insulin production in response to meals, helping the body process glucose more efficiently.

• Metformin SR (500 mg): Metformin is a biguanide that primarily works by reducing the amount of glucose produced by the liver. It also improves insulin sensitivity, helping muscles absorb glucose better. The sustained-release form ensures that Metformin is released slowly, providing a longer-lasting effect.

• Dual Action: The combination of Gliclazide and Metformin provides a dual mechanism of action — reducing glucose production from the liver (Metformin) and enhancing insulin secretion (Gliclazide), making it more effective than monotherapy.

• Sustained Release Formulation: Both drugs are in sustained-release form, ensuring consistent blood sugar control over an extended period, reducing the frequency of doses and improving patient compliance.

How to Use GLICLAGLAZE MET

1. Dosage and Administration:

   • GLICLAGLAZE MET is typically taken once or twice daily with meals, depending on the severity of the diabetes and the prescribing physician’s advice.
   • It is important to swallow the tablet whole without crushing or chewing to maintain the integrity of the sustained-release formulation.
   • Ensure regular blood sugar monitoring to adjust the dosage as needed.

2. Who Should Use It:

   • This medication is prescribed for patients with type 2 diabetes who are unable to control their blood sugar with lifestyle changes alone.
   • It is especially useful for individuals who need a combination therapy to target blood glucose regulation from multiple angles.

3. Special Considerations:

   • Patients should avoid skipping meals while on GLICLAGLAZE MET to reduce the risk of hypoglycemia.
   • Regular follow-up with the healthcare provider is important for monitoring response and adjusting the dosage.

Benefits of GLICLAGLAZE MET for Diabetes Management

1. Blood Sugar Regulation: By targeting glucose production and insulin secretion, this combination helps stabilize blood sugar levels, reducing the risk of hyperglycemia.
2. Reduction in Insulin Resistance: Metformin is well-known for improving the body’s response to insulin, which is often impaired in type 2 diabetes.
3. Long-Lasting Effects: The sustained-release nature of the medication ensures that the effect lasts throughout the day, avoiding blood sugar spikes and crashes.
4. Cardiovascular Protection: Studies show that Metformin has cardiovascular protective effects, which is a significant benefit for diabetes patients at risk of heart disease.
5. Minimal Side Effects: Due to the slow-release nature of both Gliclazide and Metformin, the risk of gastrointestinal upset (common with Metformin) and hypoglycemia (common with sulfonylureas) is minimized.

Frequently Asked Questions (FAQs)

Q1: How long does it take for GLICLAGLAZE MET to show effects?
The medication typically starts working within a few hours of ingestion, but noticeable improvements in blood sugar control are seen after consistent use over a period of days to weeks.

Q2: Can GLICLAGLAZE MET be used in type 1 diabetes?
No, this medication is only indicated for the treatment of type 2 diabetes. Patients with type 1 diabetes require insulin therapy.

Q3: What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. However, if it’s close to your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

Q4: Can I take GLICLAGLAZE MET with other diabetes medications?
In some cases, doctors may prescribe additional medications alongside GLICLAGLAZE MET to achieve better control over blood sugar levels. However, it is essential to follow your doctor’s instructions carefully to avoid the risk of hypoglycemia.

Q5: Are there any dietary restrictions while using GLICLAGLAZE MET?
Patients should follow a balanced diet rich in whole grains, lean proteins, vegetables, and fruits while avoiding sugary and high-carbohydrate foods. Consistency in meal timing is important to prevent blood sugar fluctuations.

Q6: Can this medication cause low blood sugar (hypoglycemia)?
While GLICLAGLAZE MET generally has a low risk of causing hypoglycemia, especially with its sustained-release formulation, it may still occur if meals are skipped or delayed. Symptoms of hypoglycemia include dizziness, sweating, and confusion. Always keep a sugar source handy.

Conclusion

GLICLAGLAZE MET is an effective combination therapy for the management of type 2 diabetes, offering improved glycemic control through a dual mechanism of action. The sustained-release formulations of both Gliclazide and Metformin ensure long-lasting effects, making this an ideal choice for patients needing consistent blood sugar management. With its ability to target both insulin production and insulin sensitivity, GLICLAGLAZE MET provides a comprehensive solution for diabetes care, helping to prevent complications and improve overall quality of life. Always consult your healthcare provider for personalized advice on managing your diabetes with GLICLAGLAZE MET. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

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