Atorvastatin Calcium 10mg, Fenofibrate 160mg, Ezetimibe IP 10mg – ATOVASTRIN EZ F

May 05, 2025

Effective lipid management plays a vital role in reducing the risk of cardiovascular diseases. ATOVASTRIN EZ F is a carefully formulated combination therapy that includes Atorvastatin Calcium (10mg), Fenofibrate (160mg), and Ezetimibe IP (10mg)—three proven agents that work synergistically to offer enhanced lipid control, especially for patients who do not respond adequately to single-drug therapy. This triple-action formulation targets multiple aspects of lipid metabolism: lowering LDL (bad cholesterol), reducing triglycerides, and increasing HDL (good cholesterol). As a result, ATOVASTRIN EZ F helps reduce the likelihood of atherosclerosis, heart attacks, and strokes, making it an effective treatment for high-risk cardiovascular patients.

Key Active Ingredients

  • Atorvastatin Calcium (10mg)
      
    A statin that blocks HMG-CoA reductase, the liver enzyme responsible for cholesterol production, thereby reducing LDL cholesterol levels.

  • Fenofibrate (160mg)
     
    A fibrate that stimulates PPARα (peroxisome proliferator-activated receptor alpha), promoting the breakdown of triglycerides and elevating HDL cholesterol.

  • Ezetimibe IP (10mg)
    An intestinal cholesterol absorption inhibitor that limits the uptake of both dietary and biliary cholesterol.

Together, these agents provide a comprehensive solution for mixed dyslipidemia, especially in patients with metabolic syndrome or type 2 diabetes.

Indications and Uses

ATOVASTRIN EZ F is indicated for the treatment of:

  • Primary hypercholesterolemia and mixed dyslipidemia

  • Elevated LDL-C and triglyceride levels

  • Low HDL-C levels

  • Cardiovascular risk prevention in patients requiring intensive lipid-lowering therapy

This fixed-dose combination is particularly suited for patients who are insufficiently managed by statin monotherapy or need enhanced triglyceride control.

Mechanism of Action

  • Atorvastatin suppresses cholesterol production in the liver, reducing circulating LDL-C.

  • Fenofibrate increases the catabolism of triglyceride-rich lipoproteins and boosts HDL-C.

  • Ezetimibe reduces overall cholesterol load by blocking its absorption from the intestines.

This multifaceted approach ensures a broad-spectrum lipid-lowering effect, working on different biological pathways to optimize cardiovascular outcomes.

Key Benefits

  • Effective LDL-C Reduction
    Lowers bad cholesterol to reduce plaque buildup and vascular risk.

  • Triglyceride Control
    Fenofibrate helps manage high triglycerides, minimizing the risk of pancreatitis and cardiovascular disease.

  • HDL-C Elevation
    Improves protective HDL cholesterol levels for better heart health.

  • Dual Mechanism on Cholesterol
    Atorvastatin
    and Ezetimibe together reduce both production and absorption of cholesterol.

  • Ideal for High-Risk Patients
    Especially beneficial for those with diabetes, metabolic syndrome, or existing cardiovascular disease.
     

Dosage & Administration

  • Take ATOVASTRIN EZ F once daily, preferably in the evening.

  • It can be taken with or without food.

  • Follow the dosage exactly as prescribed by your healthcare provider.

  • A balanced diet, regular physical activity, and routine lipid monitoring are recommended for optimal results.
     

Possible Side Effects

Common side effects may include:

  • Headache

  • Muscle pain or weakness

  • Nausea or digestive discomfort

  • Elevated liver enzymes

  • Slight increase in blood sugar (especially in diabetic patients)

Serious but rare side effects:

  • Rhabdomyolysis (severe muscle breakdown)

  • Liver dysfunction

  • Allergic reactions

Contact your doctor immediately if you notice unexplained muscle pain, weakness, or fatigue.

Why Choose Steris Healthcare For ATOVASTRIN EZ F

Steris Healthcare is committed to delivering advanced, clinically proven formulations that address the evolving needs of patients and healthcare professionals. ATOVASTRIN EZ F from Steris Healthcare stands out as a high-quality, triple-action lipid-lowering therapy, combining Atorvastatin Calcium, Fenofibrate, and Ezetimibe to provide comprehensive cardiovascular protection. With stringent quality control, scientifically backed ingredients, and patient-centric innovation, Steris ensures reliable efficacy and safety. Trusted by clinicians, Steris Healthcare offers a solution that supports better heart health outcomes, especially for patients requiring intensive lipid management. Choose Steris for pharmaceutical excellence and proven therapeutic value.

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