Gliclazide 60 mg – Modified Release Tablet for Type 2 Diabetes

May 05, 2025

If your doctor has prescribed Gliclazide 60 mg tablets for type 2 diabetes, you're likely looking for clear, trustworthy answers rather than scattered information across multiple sites. This guide walks through what Gliclazide 60 mg does, its key uses, how to take it correctly, and what side effects to watch for — explained simply, so you're prepared before your next doctor's visit.

GLICLAGLAZE MR 60, manufactured by Steris Healthcare Pvt Ltd, is one such Gliclazide 60 mg formulation, produced under WHO-GMP certified manufacturing standards as a modified-release (MR) tablet.

  • Gliclazide 60 mg belongs to the sulfonylurea class and is used to manage type 2 diabetes mellitus by prompting the pancreas to release more insulin.
  • It's typically available as a modified-release (MR) tablet, allowing gradual medicine release for steadier blood sugar control across the day.
  • Main uses include standalone therapy or combination treatment with medicines like metformin when lifestyle changes alone aren't enough.
  • The most common side effect is low blood sugar (hypoglycemia); mild stomach upset and headache can also occur.
  • GLICLAGLAZE MR 60 by Steris Healthcare is manufactured in a WHO-GMP certified facility for consistent quality.
  • This is a prescription-only medicine—the dosage should never be self-adjusted without medical advice.

What Is Gliclazide 60 mg Used For?

Gliclazide 60 mg tablets are used to manage blood sugar levels in adults with Type 2 Diabetes Mellitus, typically as part of a treatment plan that includes diet, physical activity, and sometimes additional diabetes medicines.

As a sulfonylurea, Gliclazide works differently from insulin-sensitizing drugs — instead of improving how the body responds to insulin, it directly stimulates the pancreas's beta cells to release more insulin, helping lower blood glucose after meals and throughout the day.

What Are the Main Uses of Gliclazide 60 mg Tablets?

Gliclazide 60 mg tablets are primarily used for long-term blood sugar management in Type 2 diabetes, especially when lifestyle changes alone haven't achieved adequate glucose control.

Common clinical uses include:

  • First-line or add-on therapy when diet and exercise alone don't sufficiently manage blood sugar.
  • Combination use with metformin or other oral antidiabetic medicines, based on individual response.
  • Long-term glycemic management, supporting reduced risk of diabetes-related complications with consistent use.

Gliclazide is not prescribed for type 1 diabetes, since its mechanism depends on the pancreas retaining some insulin-producing capacity—something type 1 diabetes patients lack.

How Does Gliclazide 60 mg Work?

Gliclazide works by stimulating pancreatic beta cells to produce and release more insulin, helping the body process glucose more efficiently and lowering blood sugar levels.

The modified-release (MR) formulation common to Gliclazide 60 mg tablets is designed to release the active ingredient gradually over roughly 24 hours. This supports steadier blood sugar management throughout the day compared to immediate-release versions, while generally allowing for convenient once-daily dosing.

How Should Gliclazide 60 mg Tablets Be Taken?

Gliclazide 60 mg MR tablets are typically taken once daily with breakfast, exactly as prescribed, and should be swallowed whole rather than crushed or split.

Practical guidance patients often need:

  1. Take it with a meal—this reduces the risk of hypoglycemia.
  2. Never crush or chew MR tablets—doing so disrupts the gradual-release mechanism.
  3. Don't skip meals after your dose, since this raises low blood sugar risk.
  4. Maintain a consistent daily schedule to support stable blood sugar levels.

What Are the Side Effects of Gliclazide 60 mg Tablets?

The most commonly reported side effect of gliclazide is low blood sugar (hypoglycemia); mild stomach discomfort and headache can also occur, while liver function changes are a rare but serious risk.

Category Examples
Common Hypoglycemia, nausea, mild stomach discomfort
Less common Headache, skin rash
Rare but serious Liver function changes, severe allergic reactions, blood cell count changes

Symptoms of hypoglycemia—shakiness, sweating, confusion, or sudden hunger—should be treated promptly with a fast-acting sugar source. Frequent episodes should always be reported to your doctor.

What Are the Benefits of Gliclazide 60 mg Tablets?

The key benefit of Gliclazide 60 mg is effective, sustained blood sugar control that helps reduce long-term diabetes-related complications when used consistently as part of a broader treatment plan.

  • Once-daily dosing convenience with the MR formulation, supporting better treatment adherence.
  • Steadier glucose control throughout the day compared to immediate-release sulfonylureas.
  • Flexibility in combination therapy, working well alongside other oral anti-diabetics when needed.

Who Should Avoid Gliclazide 60 mg?

Gliclazide is generally avoided in people with Type 1 diabetes, severe kidney or liver impairment, and known sulfonylurea allergies, and it requires extra caution in elderly patients due to increased hypoglycemia risk.

Share your complete medical history—including kidney, liver, or heart conditions—with your doctor before starting, along with all current medicines, since certain combinations increase hypoglycemia risk.

Why Choose GLICLAGLAZE MR 60 by Steris Healthcare?

GLICLAGLAZE MR 60 is manufactured by Steris Healthcare Pvt Ltd in a WHO-GMP-certified facility, reflecting consistent quality control across manufacturing.

For a chronic condition like Type 2 diabetes requiring reliable long-term dosing, manufacturing consistency directly supports predictable treatment outcomes. GLICLAGLAZE MR 60, like all Gliclazide formulations, is available strictly against a valid prescription.

Frequently Asked Questions

What is Gliclazide 60 mg used for?
It's used to manage blood sugar in Type 2 diabetes by stimulating the pancreas to release more insulin, typically alongside diet and exercise.

What are the main benefits of Gliclazide 60 mg tablets?
Benefits include sustained blood sugar control, convenient once-daily dosing with the MR formulation, and reduced long-term diabetes complications.

Can Gliclazide 60 mg cause low blood sugar?
Yes, hypoglycemia is the most common side effect, especially if meals are skipped—taking it with food helps lower this risk.

How should I take Gliclazide 60 mg MR tablets?
Once daily with breakfast, swallowed whole without crushing, exactly as your doctor prescribes.

Is Gliclazide 60 mg suitable for type 1 diabetes?
No, it's used only for Type 2 diabetes, since it relies on the pancreas retaining some insulin-producing capacity.

Does gliclazide interact with other medicines?
Yes, it can interact with other diabetes drugs, certain antibiotics, and alcohol—always share your complete medicine list with your doctor.

Conclusion

Gliclazide 60 mg tablets remain a trusted, well-studied option for managing Type 2 diabetes, particularly for patients needing more support than diet and exercise alone provide. The modified-release formulation supports steady, once-daily blood sugar control, though it requires attention to meal timing and hypoglycemia awareness.

If you've been prescribed GLICLAGLAZE MR 60, take it consistently with meals, watch for signs of low blood sugar, and avoid adjusting your dose without medical guidance. Talk to your doctor or pharmacist to confirm it's the right choice for your health profile before starting or continuing treatment.

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