PAFAGOLD 10: Uses, Dosage,Composition and More..

Apr 24, 2024

PAFAGOLD 10, formulated with Dapagliflozin 10 mg, is an advanced, highly effective oral antidiabetic medication designed for the modern management of Type 2 Diabetes Mellitus (T2DM). Manufactured by Steris Healthcare Pvt. Ltd., this medicine helps patients maintain healthy blood glucose levels while improving overall metabolic function.

As the burden of diabetes continues to rise across India, patients are increasingly seeking reliable, safe, and long-term solutions that go beyond simple sugar control. PAFAGOLD 10 delivers that promise—supporting glycaemic regulation, reducing risks associated with diabetes, and promoting better cardiovascular and renal health.

In this comprehensive guide, we explore everything you need to know about Dapagliflozin 10 mg, including its uses, benefits, dosage, mechanism of action, safety profile, precautions, side effects, FAQs, and why PAFAGOLD 10 stands out as a superior choice in the Indian pharmaceutical market.

What Is PAFAGOLD 10 (Dapagliflozin 10 mg)?

PAFAGOLD 10 contains Dapagliflozin 10 mg, a powerful SGLT2 inhibitor (Sodium-Glucose Co-Transporter-2 inhibitor). This advanced drug works by preventing glucose reabsorption in the kidney, thereby promoting glucose excretion through urine. As a modern diabetes therapy, it helps lower elevated blood sugar levels without causing insulin overload or hypoglycaemia when taken alone.

Key Features of PAFAGOLD 10

  • Contains Dapagliflozin 10 mg, a globally recommended antidiabetic agent

  • Ideal for individuals with Type 2 Diabetes

  • Helps improve long-term glycaemic control

  • Supports weight management

  • Reduces risk of cardiovascular complications

  • Offers kidney protection benefits

  • Manufactured in world-class Steris Healthcare facilities

Why Dapagliflozin 10 mg Is Important for Diabetes Control

Diabetes is not just a condition of high sugar—it affects multiple organs, including the heart, kidneys, nerves, and blood vessels. Conventional therapies often fall short in addressing all complications. Dapagliflozin 10 mg is part of a newer class of medications that target sugar regulation through the kidneys while providing multi-system benefits.

2.1 Modern Approach to Type 2 Diabetes Management

Unlike older treatments that stimulate insulin production or increase insulin sensitivity in tissues, Dapagliflozin works by:

  • Reducing glucose load on kidneys

  • Promoting steady sugar excretion

  • Reducing excess glucose accumulation

This novel mechanism offers a safer, long-lasting approach for patients with uncontrolled diabetes.

2.2 Better Tolerance and Reduced Side Effects

When used alone, Dapagliflozin rarely causes hypoglycaemia—making it a safer option for long-term therapy.

Mechanism of Action – How Dapagliflozin 10 mg Works

Understanding how PAFAGOLD 10 works helps patients appreciate why it is considered a breakthrough therapy.

3.1 Role of the Kidneys in Glucose Control

The kidneys filter around 180 grams of glucose daily. Most of this is reabsorbed back into the body by SGLT2 proteins located in the proximal renal tubules.

3.2 What Dapagliflozin Does

Dapagliflozin blocks the SGLT2 protein, preventing reabsorption of glucose.
Instead, glucose is eliminated through urine.

Direct Effects

  • Lower blood sugar

  • Reduced HbA1c

  • Lower fasting glucose levels

  • Lower post-meal glucose spikes

Indirect Effects

  • Weight loss through calorie excretion

  • Lower blood pressure

  • Improved cardiovascular health

  • Improved kidney function

Uses of PAFAGOLD 10 (Dapagliflozin 10 mg)

PAFAGOLD 10 is commonly prescribed for:

4.1 Type 2 Diabetes Mellitus

  • Helps control high blood sugar

  • Reduces HbA1c levels

  • Improves long-term glycaemic stability

4.2 Weight Management in Diabetic Patients

Dapagliflozin promotes calorie excretion, helping in:

  • Fat reduction

  • Decrease in BMI

  • Better metabolic profile

4.3 Cardiovascular Benefits

Research shows dapagliflozin helps reduce the risk of:

  • Heart failure-related hospitalizations

  • Cardiovascular-related deaths

4.4 Kidney Protection

Dapagliflozin improves kidney outcomes by:

  • Reducing albuminuria

  • Decreasing glomerular pressure

  • Improving kidney filtration efficiency

4.5 Combination Therapy

PAFAGOLD 10 can be used alone or along with:

  • Metformin

  • Glimepiride

  • Sitagliptin

  • Insulin

Benefits of PAFAGOLD 10 (Dapagliflozin 10 mg)

5.1 Helps Achieve Steady Blood Sugar Control

Dapagliflozin ensures better glucose regulation with minimal fluctuation throughout the day.

5.2 Low Hypoglycaemia Risk

Unlike sulfonylureas (e.g., glimepiride), Dapagliflozin has a negligible chance of causing dangerously low sugar levels when used alone.

5.3 Supports Weight Loss

Patients typically lose 2–3 kg within a few months due to calorie loss through urine.

5.4 Improves Heart Function

Particularly beneficial in preventing heart failure.

5.5 Reduces Blood Pressure

Acts as a mild diuretic, helping reduce fluid overload.

5.6 Enhances Kidney Health

Delays kidney disease progression, which is extremely important for diabetic patients.

5.7 Provides All-Day Sugar Control

Effective 24-hour action with once-daily dosing.

Dosage & Administration

6.1 Recommended Dose

  • PAFAGOLD 10 (Dapagliflozin 10 mg)
    Usual dose: One tablet once daily

6.2 How to Take

  • Swallow with water

  • Can be taken with or without food

  • Take daily at the same time

6.3 Missed Dose

  • Take it as soon as you remember

  • Skip if close to next dose

  • Do NOT double the dose

6.4 Overdose

May lead to excessive urination and dehydration; consult a doctor immediately.

Side Effects

Though generally well tolerated, some patients may experience:

7.1 Common Side Effects

  • Frequent urination

  • Urinary tract infections

  • Weight loss

  • Dehydration

  • Dizziness

  • Thirst

  • Mild blood pressure drop

7.2 Rare Side Effects

  • Ketoacidosis

  • Severe dehydration

  • Kidney issues

  • Serious urinary infections

  • Genital fungal infections

Patients should seek medical help if they observe unusual symptoms.

Precautions and Warnings

8.1 Avoid If You Have

  • Type 1 diabetes

  • Severe kidney disease

  • Severe liver impairment

  • Active urinary infections

8.2 Warnings

  • Maintain hydration

  • Monitor kidney function regularly

  • Avoid alcohol consumption

  • Inform doctor before surgery

8.3 Pregnancy & Breastfeeding

Use only under strict medical supervision.

Interactions

Dapagliflozin may interact with:

  • Diuretics (risk of dehydration)

  • Insulin (increased risk of low sugar)

  • Blood pressure medicines

  • SGLT2 inhibitor combinations

Always share your medication history with your doctor.

Why PAFAGOLD 10 from Steris Healthcare Is the Best Choice

PAFAGOLD 10 stands out in the Indian market due to:

10.1 Superior Pharmaceutical Quality

Manufactured using premium-grade API, ensuring purity and high bioavailability.

10.2 Trusted by Healthcare Professionals

Steris Healthcare is recognized for its commitment to safety, efficacy, and reliable supply.

10.3 Affordable Yet High-Quality Medication

Accessible pricing tailored to Indian patients without compromising quality standards.

10.4 Consistent Performance

Each batch undergoes strict quality checks to ensure consistent therapeutic effect.

10.5 Patient-Centric Packaging

Designed for ease of use, proper storage, and improved shelf-stability.

Why Dapagliflozin 10 mg Is a Preferred Choice in India

With rising diabetes cases, Indian doctors prefer SGLT2 inhibitors like dapagliflozin for their:

  • Blood sugar control

  • Blood pressure benefits

  • Weight loss support

  • Renal-protective action

  • Heart protection

This makes PAFAGOLD 10 an ideal choice for holistic diabetes management.

Summary

PAFAGOLD 10 (Dapagliflozin 10 mg) is a powerful, reliable, and modern solution for managing Type 2 Diabetes effectively. Its once-daily dose, combined with its multi-system health benefits, makes it an essential therapy for diabetic patients.

Frequently Asked Questions 

1. What is Dapagliflozin 10 used for?

It helps manage Type 2 Diabetes, improves heart and kidney health, and supports weight loss.

2. How long does it take to work?

Patients may notice improvements in sugar levels within 1–2 weeks.

3. Can I take it with other diabetes medicines?

Yes, it is often prescribed with metformin, glimepiride, or insulin.

4. Will it cause low blood sugar?

Not usually, unless combined with insulin or sulfonylureas.

5. Is it safe for long-term use?

Yes, under medical supervision.

6. Can it be taken at night?

Yes, but taking it at the same time daily is important.

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