Esmostrum LSR: Uses, Side Effects, Dosage, Interactions, and More information...

ESMOSTRUM LS 

Levosulpiride (75mg), Esomeprazole (40mg)

ESMOSTRUM LS combines two powerful medications, Levosulpiride (75mg) and Esomeprazole (40mg), to provide a comprehensive solution for gastrointestinal disorders. This medication is designed to manage symptoms associated with gastroesophageal reflux disease (GERD), functional dyspepsia, and other related conditions. By understanding the components and their synergistic effects, patients and healthcare providers can make informed decisions about its use.

Components of ESMOSTRUM LS

Levosulpiride (75mg)

Levosulpiride is an antipsychotic and prokinetic agent that belongs to the benzamide class. It is primarily used to enhance gastrointestinal motility and alleviate symptoms of nausea and vomiting. Levosulpiride acts by blocking dopamine D2 receptors in the gut, which helps in regulating gastric emptying and improving motility.

Key Benefits of Levosulpiride:

• Enhanced Gastric Motility: Levosulpiride improves the movement of the stomach and intestines, facilitating better digestion and reducing symptoms of dyspepsia.
• Anti-Nausea Effects: It helps in reducing nausea and vomiting by acting on the central and peripheral dopamine receptors.
• Mood Stabilization: Although primarily used for gastrointestinal issues, Levosulpiride also has mild antidepressant and anxiolytic properties due to its action on dopamine receptors in the brain.

Esomeprazole (40mg)

It is widely used in the treatment of conditions like GERD, peptic ulcer disease, and Zollinger-Ellison syndrome.

Key Benefits of Esomeprazole:

• Acid Suppression: Esomeprazole significantly reduces gastric acid secretion, helping to manage conditions like GERD and peptic ulcers.
• Healing of Erosive Esophagitis: Esomeprazole promotes the healing of the esophageal lining damaged by stomach acid.

Uses of ESMOSTRUM LS

ESMOSTRUM LS is prescribed for the treatment of various gastrointestinal disorders, particularly those involving acid reflux and motility issues. Some common uses include:

Gastroesophageal Reflux Disease (GERD)

The combination of Levosulpiride and Esomeprazole in ESMOSTRUM LS helps manage GERD symptoms by enhancing gastric motility and reducing acid production.

Functional Dyspepsia

Functional dyspepsia, characterized by upper abdominal discomfort, bloating, and nausea, can significantly impact quality of life. Levosulpiride improves gastric emptying and motility, while Esomeprazole reduces acid production, providing comprehensive relief from dyspeptic symptoms.

Peptic Ulcer Disease

Peptic ulcer disease involves the formation of ulcers in the stomach or duodenum due to excessive acid production. Esomeprazole helps in reducing acid secretion, promoting ulcer healing, while Levosulpiride aids in managing associated gastrointestinal discomfort.

Zollinger-Ellison Syndrome

 Esomeprazole is effective in managing acid hypersecretion, and the prokinetic action of Levosulpiride can help alleviate associated gastrointestinal symptoms.

Dosage and Administration

The typical dosage of ESMOSTRUM LS involves one tablet per day, taken before meals. It is crucial to follow the prescribed dosage and administration instructions provided by the healthcare provider to ensure optimal effectiveness and safety.

Special Considerations:

• Kidney or Liver Impairment: Patients with renal or hepatic impairment should use ESMOSTRUM LS with caution, and dosage adjustments may be necessary.
• Elderly Patients: Elderly patients may be more susceptible to adverse effects and should be monitored closely during treatment.
• Pregnancy and Lactation: The safety of ESMOSTRUM LS during pregnancy and lactation has not been fully established. It should be used only if the potential benefits outweigh the risks.

Potential Side Effects

Like all medications, ESMOSTRUM LS may cause side effects in some patients. It is essential to be aware of potential adverse reactions and seek medical attention if any severe or persistent symptoms occur.

Common Side Effects:

• Headache: Mild headaches may occur, particularly during the initial stages of treatment.
• Nausea and Vomiting: While Levosulpiride is used to treat nausea, some patients may still experience these symptoms.
• Diarrhea or Constipation: Gastrointestinal disturbances, including diarrhea or constipation, can occur with Esomeprazole.

Serious Side Effects:

• Allergic Reactions: Severe allergic reactions, including rash, itching, swelling, or difficulty breathing, require immediate medical attention.
• Severe Abdominal Pain: Persistent or severe abdominal pain may indicate a more serious underlying condition and should be evaluated by a healthcare provider.
• Mental Health Changes: Although rare, Levosulpiride may cause mood changes, agitation, or confusion in some patients.

Interactions with Other Medications

ESMOSTRUM LS can interact with other medications, potentially affecting their efficacy or increasing the risk of adverse effects. It is essential to inform the healthcare provider about all current medications, including over-the-counter drugs and supplements.

Common Interactions:

• Antacids: Antacids may reduce the absorption of Esomeprazole. It is advisable to space out the administration of antacids and ESMOSTRUM LS.
• Warfarin: Esomeprazole can increase the effects of warfarin, a blood thinner, potentially leading to an increased risk of bleeding.
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Precautions and Warnings

Clostridium difficile Infection:

• Increased Risk: Use of PPIs has been associated with an increased risk of Clostridium difficile infection, particularly in hospitalized patients.

Conclusion

ESMOSTRUM LS, a combination of Levosulpiride (75mg) and Esomeprazole (40mg), offers a comprehensive solution for managing gastrointestinal disorders such as GERD, functional dyspepsia, and peptic ulcer disease. By improving gastric motility and reducing acid production, ESMOSTRUM LS provides effective relief from symptoms and promotes healing. As with any medication, it is essential to use ESMOSTRUM LS under the guidance of a healthcare provider, adhering to the prescribed dosage and monitoring for potential side effects and interactions. With proper use, ESMOSTRUM LS can significantly improve the quality of life for patients suffering from gastrointestinal disorders. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

For further information 

Email: info@sterispharma.com /  contact@sterispharma.com

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