Empagliflozin and Metformin Hydrochloride Tablets for Type 2 Diabetes

Introduction to GLIEMPAFLOZIN MET 12.5mg/500mg

GLIEMPAFLOZIN MET 12.5mg/500mg is a powerful fixed-dose combination tablet containing Empagliflozin 12.5 mg and Metformin Hydrochloride 500 mg. It is designed to manage Type 2 Diabetes Mellitus (T2DM) in adults and is an ideal option for patients requiring dual therapy to control their blood glucose levels.This combination belongs to a new era of diabetes treatment that not only regulates blood sugar but also offers cardiovascular and renal protection.

Composition

• Empagliflozin: 12.5 mg

• Metformin Hydrochloride (Immediate/Extended Release): 500 mg

This fixed dose combination of empagliflozin and metformin hydrochloride tablets helps in reducing blood glucose levels through dual mechanisms.

Key Features of GLIEMPAFLOZIN MET

• Contains empagliflozin and metformin hydrochloride extended release tablets for sustained effect.

• Ideal for adults with type 2 diabetes not adequately controlled by metformin alone.

• Helps in weight management and reduces cardiovascular risk.

• Convenient once or twice daily oral administration.

• Improved glycemic control with fewer chances of hypoglycemia.

How GLIEMPAFLOZIN MET 12.5mg/500mg Works

1. Empagliflozin (12.5 mg)

A SGLT2 inhibitor, empagliflozin works by:

• Blocking the sodium-glucose co-transporter 2 (SGLT2) in the kidneys.

• Preventing glucose reabsorption in the kidneys.

• Promoting glucose excretion through urine.

• Reducing blood sugar and helping in weight loss and blood pressure control.

2. Metformin Hydrochloride (500 mg)

A biguanide, metformin:

• Reduces hepatic glucose production.

• Increases insulin sensitivity.

• Improves peripheral glucose uptake.

Together, this dual therapy provides a comprehensive approach to managing type 2 diabetes.

Uses of GLIEMPAFLOZIN MET (empagliflozin 12.5 mg+metformin 500 mg)

The fixed dose combination of empagliflozin and metformin hydrochloride tablets is primarily used for:

• Managing Type 2 Diabetes Mellitus in adults.

• Reducing the risk of cardiovascular death in diabetic patients with heart disease.

• Assisting with weight management in overweight patients.

• Supporting kidney function in diabetic nephropathy.

This formulation is most effective when combined with diet, exercise, and lifestyle modifications.

Benefits of Empagliflozin 12.5 mg Metformin 500 mg Combination

•  Glycemic Control

Effectively reduces fasting and postprandial blood glucose levels.

•  Weight Loss

Unlike other diabetic drugs, empagliflozin may help reduce body weight.

•  Low Risk of Hypoglycemia

Especially beneficial for patients prone to low blood sugar levels.

•  Cardiovascular Protection

Proven to reduce cardiovascular-related deaths in Type 2 diabetic patients.

•  Renal Benefits

Helps slow the progression of diabetic kidney disease.

Dosage & Administration

• Typically prescribed as one tablet once or twice daily after meals.

• The dose may be adjusted by the physician depending on:

  • Blood glucose levels

  • Kidney function

  • Tolerance to metformin

Always take this medication as directed by your healthcare provider.

Empagliflozin Side Effects and Safety Information

Common Side Effects:

• Increased urination

• Thirst

• Urinary tract infections (UTI)

• Genital fungal infections

• Mild gastrointestinal discomfort (due to metformin)

Less Common but Serious Side Effects:

• Lactic acidosis (rare but serious – metformin-related)

• Dehydration

• Low blood pressure

• Ketoacidosis (rare)

Precautions:

• Not for use in Type 1 Diabetes.

• Not recommended in patients with severe kidney impairment.

• Caution in elderly patients or those on diuretics.

• Stay well-hydrated to prevent kidney problems.

Consult your doctor if you experience symptoms like fatigue, shortness of breath, or muscle pain.

Who Should Use GLIEMPAFLOZIN MET?

• Adults with Type 2 Diabetes who are inadequately controlled on metformin alone.

• Patients with a high risk of cardiovascular events.

• Those looking for dual therapy in a single convenient tablet.

• Individuals concerned with weight gain and insulin resistance.

Who Should Not Use It?

• Patients with Type 1 Diabetes

• Individuals with severe kidney disease or on dialysis

• Pregnant or breastfeeding women (unless advised by doctor)

• Patients with a history of lactic acidosis

Pricing & Availability

GLIEMPAFLOZIN MET 12.5mg/500mg is available at leading pharmacies across India and through authorized distributors.

Price may vary depending on location, manufacturer, and pack size. Contact your nearest distributor or hospital pharmacy for the latest price.

Why Choose GLIEMPAFLOZIN MET 12.5mg/500mg?

• Combines two proven anti-diabetic agents in one tablet.

• Provides fast and effective glycemic control.

• Clinically tested for heart and kidney protection.

• Easy to swallow and well-tolerated.

• Made under WHO-GMP certified manufacturing facilities.

Frequently Asked Questions (FAQs)

Q1. What is GLIEMPAFLOZIN MET 12.5mg/500mg used for?

It is used to treat Type 2 Diabetes Mellitus and reduce the risk of heart and kidney complications in diabetic patients.

Q2. What are the side effects of empagliflozin and metformin hydrochloride tablets?

Common side effects include increased urination, UTI, and nausea. Rare but serious effects include lactic acidosis and ketoacidosis.

Q3. Can I take GLIEMPAFLOZIN MET on an empty stomach?

It is recommended to take it after meals to minimize stomach upset due to metformin.

Q4. Is it safe for kidney patients?

Caution is required. It should be avoided in patients with severely reduced kidney function. Your doctor will evaluate suitability.

Q5. Is this combination better than using empagliflozin or metformin alone?

Yes. The fixed dose combination of empagliflozin and metformin hydrochloride tablets offers better glycemic control than either drug alone and adds cardio-renal benefits.

Conclusion

If you’re managing Type 2 Diabetes and need enhanced glucose control with added cardiovascular and renal protection, GLIEMPAFLOZIN MET 12.5mg/500mg is an ideal, advanced treatment option. With the trusted combination of empagliflozin and metformin hydrochloride, it empowers diabetic patients to live healthier, longer, and better lives.