Empagliflozin and Metformin Hydrochloride Tablets Uses, Dosage, and Side Effects

Introduction

Controlling type 2 diabetes requires more than just glucose-lowering—it demands a comprehensive treatment that supports heart, kidney, and metabolic health. That’s where GLIEMPAFLOZIN MET ER steps in.This advanced fixed dose combination of empagliflozin and metformin hydrochloride tablets offers dual-action therapy for long-term glycemic control and added cardiovascular protection. It is specially formulated with empagliflozin 25 mg and metformin hydrochloride 1000 mg (extended release), providing both strength and convenience in one daily tablet.

What is GLIEMPAFLOZIN MET ER?

GLIEMPAFLOZIN MET ER is a combination of two well-known antidiabetic agents:

• Empagliflozin 25 mg – a sodium-glucose co-transporter 2 (SGLT2 inhibitor)

• Metformin Hydrochloride 1000 mg (ER) – a first-line oral antidiabetic from the biguanide class

Together, they deliver synergistic blood sugar control by reducing glucose production and promoting glucose excretion via the kidneys.

Key Features

• Contains empagliflozin 25 mg + metformin 1000 mg ER

• Dual mechanism: targets insulin resistance & glucose reabsorption

• Once-daily extended-release formula

• Helps lower HbA1c, fasting, and post-meal sugar levels

• Promotes weight loss and mild blood pressure reduction

• Reduces risk of cardiovascular death in high-risk patients

• Shown to slow progression of diabetic kidney disease

How Does GLIEMPAFLOZIN MET ER Work?

 Empagliflozin 25 mg

• Blocks SGLT2 in kidneys, preventing glucose reabsorption

• Causes excess sugar to be excreted through urine

• Works independently of insulin

• Also provides cardiovascular and renal protection

 Metformin Hydrochloride 1000 mg (ER)

• Reduces hepatic glucose production

• Improves insulin sensitivity in muscles and fat tissues

• Extended-release form reduces gastrointestinal side effects

• Enhances overall glycemic control

Together, this fixed dose combination of empagliflozin and metformin hydrochloride tablets provides robust blood sugar management with added health benefits.

Benefits of GLIEMPAFLOZIN MET ER

 1. Effective Glycemic Control

• Lowers fasting and postprandial blood glucose

• Improves HbA1c levels effectively

 2. Weight Reduction

• Empagliflozin promotes calorie loss through urinary glucose

• Helps manage body weight without the need for insulin

 3. Cardiovascular Benefits

• Empagliflozin 25 mg is proven to reduce the risk of:

  • Cardiovascular death

  • Hospitalization for heart failure

 4. Renal Protection

• Helps delay progression of chronic kidney disease in diabetics

 5. Once-Daily Convenience

• Extended-release formulation enables once-daily dosing

• Improved patient compliance and lifestyle flexibility

Indications (Uses)

This combination is recommended for:

• Adults with Type 2 Diabetes Mellitus

• Patients inadequately controlled with metformin alone

• Diabetics with high cardiovascular or kidney risk

• Those who need both weight and sugar control

 Note: Not for use in Type 1 diabetes or diabetic ketoacidosis.

Dosage and Administration

• Typical Dose: 1 tablet once daily with meals

• Tablet Form: Oral, film-coated, extended release

• Do not split or crush the tablet

Your doctor will determine the ideal dose based on your blood glucose levels, kidney function, and overall health.

Empagliflozin 25 mg Side Effects

While generally safe, empagliflozin 25 mg tablet may cause:

Common Side Effects:

• Increased urination

• Genital yeast infections

• Mild dehydration or thirst

• Urinary tract infections

Rare but Serious:

• Ketoacidosis (even with normal sugar levels)

• Low blood pressure

• Acute kidney injury (in predisposed patients)

Stay hydrated and monitor for symptoms like nausea, vomiting, or fatigue.

Metformin 1000 mg Side Effects

Common:

• Nausea

• Bloating

• Diarrhea (usually mild with ER version)

Serious:

• Lactic acidosis (very rare but serious)

• Avoid in patients with severe kidney or liver dysfunction

Precautions and Warnings

• Not suitable during pregnancy or breastfeeding

• Avoid alcohol to reduce lactic acidosis risk

• Regular monitoring of kidney function and blood sugar is necessary

• Not recommended for patients with eGFR < 45 ml/min

Storage Instructions

• Store below 30°C in a cool, dry place

• Keep away from moisture and direct sunlight

• Keep out of reach of children

GLIEMPAFLOZIN MET ER Price in India

• May vary depending on the brand and pharmacy location

• Available at leading chemists and verified online platforms

Why Choose GLIEMPAFLOZIN MET ER?

• Backed by evidence-based clinical studies

• Combines two leading diabetes drugs

• Targets blood sugar, weight, and organ protection together

• Offers convenience with once-daily dosing

• Manufactured in GMP and WHO-compliant facilities

Call to Action: Take Charge of Your Diabetes Today!

Don’t settle for partial control. With GLIEMPAFLOZIN MET ER, experience a holistic approach to managing diabetes that’s not just about sugar, but about your heart, kidneys, weight, and longevity.

• Ask your doctor today about GLIEMPAFLOZIN MET ER.
• Buy from trusted pharmacies only.
• Live empowered, live better.

Frequently Asked Questions (FAQs)

Q1. What is GLIEMPAFLOZIN MET ER used for?

It is used to treat type 2 diabetes in adults who require both empagliflozin 25 mg and metformin hydrochloride 1000 mg for effective blood sugar control.

Q2. Can empagliflozin 25 mg and metformin be taken together?

Yes, and they are often combined into one tablet for convenience and enhanced therapeutic benefits.

Q3. What is the best time to take GLIEMPAFLOZIN MET ER?

It is best taken once daily with food, preferably in the morning, to reduce stomach upset.

Q4. Does this combination cause hypoglycemia?

Not usually, as both drugs do not cause insulin release. However, risk increases if taken with sulfonylureas or insulin.

Q5. Can GLIEMPAFLOZIN MET ER help with weight loss?

Yes, empagliflozin promotes weight reduction by excreting glucose in urine, which also helps improve insulin sensitivity.

Conclusion

GLIEMPAFLOZIN MET ER brings together the trusted power of metformin 1000 mg and the innovative benefits of empagliflozin 25 mg in a single, easy-to-use tablet. This fixed dose combination of empagliflozin and metformin hydrochloride extended release tablets is a smart choice for those seeking total diabetes care, including blood sugar control, cardiovascular protection, weight management, and kidney support.Stay in control of your diabetes with GLIEMPAFLOZIN MET ER—because your health deserves nothing less than comprehensive care.