Dapagliflozin (10mg) & GLIDAPAFLOZIN 10  Tablet - Steris Healthcare PVT LTD………

Diabetes has become one of the most serious health challenges in India, affecting people at younger ages due to lifestyle changes, poor dietary habits, stress, and lack of physical activity. Type 2 diabetes mellitus not only leads to high blood sugar levels but also increases the risk of heart disease, kidney damage, nerve problems, and vision loss if not managed properly.

GLIDAPAFLOZIN 10 Tablet, containing Dapagliflozin 10 mg, is a modern oral antidiabetic medicine that helps control blood sugar levels in adults with type 2 diabetes. It works through a unique mechanism by removing excess glucose from the body via urine, rather than increasing insulin levels. This makes it an effective and well-tolerated option for long-term diabetes management.

In addition to blood sugar control, dapagliflozin has shown added benefits for heart and kidney health, making GLIDAPAFLOZIN 10 an important medicine in comprehensive diabetes care.

Composition of GLIDAPAFLOZIN 10

Each tablet of GLIDAPAFLOZIN 10 contains:

• Dapagliflozin – 10 mg

Dapagliflozin belongs to a class of medicines called SGLT2 inhibitors.

What is Dapagliflozin?

Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor. It works on the kidneys to reduce glucose reabsorption, allowing excess sugar to be excreted through urine. This insulin-independent mechanism makes dapagliflozin effective even in later stages of type 2 diabetes.

Apart from controlling blood glucose, dapagliflozin also helps with:

• Mild weight reduction

• Blood pressure control

• Cardiovascular protection

• Kidney function support

How GLIDAPAFLOZIN 10 Works

Normally, kidneys filter glucose from the blood and reabsorb it back into the bloodstream. In people with diabetes, this process contributes to persistently high blood sugar levels.

GLIDAPAFLOZIN 10 blocks the SGLT2 protein in the kidneys, which:

• Reduces glucose reabsorption

• Increases glucose excretion through urine

• Lowers blood sugar levels effectively

This action does not depend on insulin, reducing the risk of low blood sugar when used alone.

Uses of GLIDAPAFLOZIN 10 Tablet

1. Type 2 Diabetes Mellitus

GLIDAPAFLOZIN 10 is primarily used to:

• Control high blood sugar levels

• Improve long-term glycaemic control

• Reduce HbA1c levels

It can be prescribed alone or in combination with other antidiabetic medicines such as metformin, DPP-4 inhibitors, or insulin.

2. Cardiovascular Risk Reduction

Dapagliflozin has demonstrated cardiovascular benefits, especially in patients with:

• Type 2 diabetes and heart disease

• High risk of heart failure

GLIDAPAFLOZIN 10 helps reduce hospitalisation due to heart failure and supports overall heart health.

3. Kidney Protection in Diabetic Patients

Long-standing diabetes can damage the kidneys. GLIDAPAFLOZIN 10 helps:

• Slow the progression of diabetic kidney disease

• Reduce stress on kidney filtration system

This makes it particularly beneficial for diabetic patients with early kidney involvement.

4. Weight and Blood Pressure Management (Additional Benefits)

GLIDAPAFLOZIN 10 may also help with:

• Mild weight loss due to glucose excretion

• Reduction in systolic blood pressure

These added benefits support overall metabolic health.

Benefits of GLIDAPAFLOZIN 10

• Effective blood sugar reduction

• Works independently of insulin

• Low risk of hypoglycaemia when used alone

• Supports heart and kidney health

• Helps with mild weight loss

• Once-daily dosing for better compliance

• Suitable for long-term diabetes management

Dosage and Administration

Recommended Dosage

• One tablet (10 mg) once daily, or as prescribed by the doctor

The dose may vary depending on individual health condition, kidney function, and combination therapy.

How to Take GLIDAPAFLOZIN 10

• Take the tablet with water

• Can be taken with or without food

• Preferably take at the same time each day

Missed Dose and Overdose

Missed Dose

• Take the missed dose as soon as you remember

• Skip if it is almost time for the next dose

• Do not take double dose

Overdose

Overdose may increase the risk of dehydration or low blood pressure. Seek medical attention immediately if overdose is suspected.

Side Effects of GLIDAPAFLOZIN 10

GLIDAPAFLOZIN 10 is generally well tolerated, but some patients may experience side effects.

Common Side Effects

• Increased urination

• Genital fungal infections

• Urinary tract infections

• Mild dehydration

Less Common Side Effects

• Dizziness

• Low blood pressure

• Increased thirst

Rare but Serious Side Effects

• Ketoacidosis (rare but serious)

• Severe urinary infections

• Allergic reactions

Consult a doctor immediately if severe symptoms occur.

Precautions and Warnings

Before taking GLIDAPAFLOZIN 10, inform your doctor if you have:

• Kidney disease

• Recurrent urinary infections

• Low blood pressure

• Dehydration

• Liver problems

Use in Elderly Patients

Elderly patients may be more prone to dehydration and low blood pressure. Close monitoring is advised.

Pregnancy and Breastfeeding

• Not recommended during pregnancy

• Avoid use during breastfeeding unless advised by a doctor

Alcohol Consumption

Alcohol may increase the risk of dehydration and low blood sugar. Limit alcohol intake while on GLIDAPAFLOZIN 10.

Drug Interactions

GLIDAPAFLOZIN 10 may interact with:

• Diuretics

• Insulin or insulin secretagogues

• Blood pressure medicines

Always inform your doctor about all medicines you are taking.

Who Should Avoid GLIDAPAFLOZIN 10?

• Patients with type 1 diabetes

• Patients with severe kidney failure

• Individuals with diabetic ketoacidosis

• Patients allergic to dapagliflozin

GLIDAPAFLOZIN 10 in Indian Diabetes Care

India is often called the “diabetes capital of the world.” Early onset of diabetes and poor glycaemic control have led to increased complications. GLIDAPAFLOZIN 10 fits well into modern diabetes treatment protocols in India by offering effective sugar control along with heart and kidney protection.

Its once-daily dosing and additional metabolic benefits make it suitable for working professionals, elderly patients, and those requiring combination therapy.

Lifestyle Advice with GLIDAPAFLOZIN 10

For best results, patients should:

• Follow a balanced diabetic diet

• Exercise regularly

• Maintain proper hydration

• Monitor blood sugar levels

• Attend regular medical check-ups

Storage Instructions

• Store below 25°C

• Keep away from moisture and heat

• Keep out of reach of children

Why Choose GLIDAPAFLOZIN 10?

• Modern SGLT2 inhibitor therapy

• Proven blood sugar control

• Added heart and kidney benefits

• Convenient once-daily dosing

• Trusted option for long-term diabetes management

Conclusion

GLIDAPAFLOZIN 10 Tablet, containing Dapagliflozin 10 mg, is an effective and advanced treatment option for managing type 2 diabetes mellitus. By removing excess glucose through the kidneys, it helps achieve better glycaemic control while also offering cardiovascular and renal protection.

Frequently Asked Questions 

Is GLIDAPAFLOZIN 10 insulin?

No, it is an oral antidiabetic medicine and does not contain insulin.

Can GLIDAPAFLOZIN 10 be taken with metformin?

Yes, it is commonly prescribed in combination with metformin.

Does GLIDAPAFLOZIN 10 cause hypoglycaemia?

When used alone, the risk is low. Risk may increase when combined with insulin or sulfonylureas.

Can GLIDAPAFLOZIN 10 help with weight loss?

It may cause mild weight reduction due to glucose loss through urine.

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