Cyclosporine 100 mg is an immunosuppressive drug that has been a cornerstone of modern transplant medicine and autoimmune therapy for over four decades. It was first isolated from the fungus Tolypocladium inflatum in 1970 and has since transformed organ transplantation from a high-failure procedure into a life-saving routine.

CYCLOPURE 100, manufactured by Steris Healthcare, delivers exactly 100 mg of cyclosporine in a soft gelatin capsule, ensuring precise dosing and consistent bioavailability. Steris Healthcare formulates CYCLOPURE 100 under strict GMP-compliant conditions, making it a trusted cyclosporine 100 mg brand name in the Indian pharmaceutical market and an increasingly preferred option for doctors looking for a reliable cyclosporine 100 mg capsule.

The drug works by selectively suppressing certain immune cells — primarily T-lymphocytes — that are responsible for attacking foreign tissue or, in autoimmune diseases, the body's own tissues. Unlike broad-spectrum immunosuppressants, cyclosporine acts with a degree of selectivity that preserves basic immune function while preventing rejection or autoimmune damage.

CYCLOPURE 100 is available both through hospital pharmacies and online platforms. Patients and healthcare providers looking for cyclosporine 100 mg online will find Steris Healthcare's CYCLOPURE 100 listed as one of the competitively priced options in India.

 

What Is Cyclosporine 100 mg Used For?

Cyclosporine 100 mg is prescribed across a broad spectrum of clinical situations. The FDA and India's CDSCO have approved it for multiple indications. Below are the primary conditions for which CYCLOPURE 100 is prescribed.

Cyclosporine 100 mg for Kidney Transplant

Organ transplant patients require lifelong immunosuppression to prevent their immune system from recognising the donor organ as "foreign" and mounting a rejection response. Cyclosporine 100 mg is one of the oldest and most well-established drugs in post-transplant regimens.

After a kidney transplant, CYCLOPURE 100 is typically used in combination with corticosteroids and other immunosuppressants. The goal is to keep the patient's immune system suppressed enough to prevent rejection but active enough to fight infections. Studies consistently show that cyclosporine-based regimens significantly reduce acute rejection episodes in the first year post-transplant. For kidney transplant recipients in India, CYCLOPURE 100 offers a quality cyclosporine 100 mg capsule at a competitive tablet price compared to multinational brands.

Cyclosporine for Autoimmune Diseases

Beyond transplantation, cyclosporine 100 mg has become a valuable tool in managing autoimmune conditions where the immune system turns on the body's own tissues. These include:

• Nephrotic syndrome – reduces proteinuria and induces remission
• Uveitis – controls inflammation in the eye that can lead to blindness
• Aplastic anaemia – used when bone marrow transplant is not possible
• Inflammatory bowel disease – especially severe ulcerative colitis

In all these conditions, CYCLOPURE 100 provides consistent delivery of the 100 mg dose that physicians rely on for effective immunosuppression.

Cyclosporine for Psoriasis Treatment

Cyclosporine 100 mg for psoriasis is one of its most widely used off-label and on-label applications. Psoriasis is a chronic autoimmune skin condition characterised by rapid skin cell turnover, leading to thick, scaly plaques. T-lymphocytes play a central role in this pathology — and since cyclosporine is a potent T-cell suppressor, it works exceptionally well in moderate-to-severe psoriasis.

In clinical practice, cyclosporine 100 mg tablets or capsules are used in patients who have not responded adequately to topical treatments, light therapy, or methotrexate. CYCLOPURE 100 is a practical choice for dermatologists managing such patients, offering an affordable cyclosporine 100 mg best price in India from Steris Healthcare.

Treatment courses are usually limited to 12–16 weeks at a time to minimize side effects, with some patients cycling on and off therapy.

Cyclosporine for Rheumatoid Arthritis

In rheumatoid arthritis (RA), the immune system attacks joint lining (synovium), causing pain, swelling, and eventual joint damage. Cyclosporine 100 mg is used as a disease-modifying antirheumatic drug (DMARD), often combined with methotrexate in patients who have inadequate response to methotrexate alone.

CYCLOPURE 100 helps reduce joint inflammation, morning stiffness, and the progression of joint erosion. As part of Steris Healthcare's portfolio, it gives rheumatologists an accessible cyclosporine 100 mg brand name in India to prescribe confidently.

 

Is Cyclosporine 100 mg a Steroid or Not?

This is one of the most common questions patients ask, and the answer is clear: Cyclosporine is NOT a steroid.

Steroids (corticosteroids like prednisolone or dexamethasone) suppress the immune system broadly by acting on glucocorticoid receptors throughout the body. They carry a well-known risk profile including weight gain, blood sugar elevation, bone loss, and skin thinning.

Cyclosporine belongs to a completely different drug class — calcineurin inhibitors. It works by blocking calcineurin, an enzyme that activates T-cells. The mechanism is entirely distinct from steroids, and so are the side effects. While cyclosporine does carry its own risks (particularly kidney toxicity and elevated blood pressure), it does not cause the characteristic steroid side effects.

Patients prescribed CYCLOPURE 100 can be reassured that they are taking a targeted immunosuppressant, not a steroid. This distinction matters because some patients are steroid-intolerant or steroid-resistant — cyclosporine provides an alternative route to immune suppression for such individuals.

 

How Does Cyclosporine 100 mg Work?

Understanding the mechanism of action helps patients and caregivers appreciate why proper dosing and blood level monitoring are essential.

After you swallow a CYCLOPURE 100 capsule, cyclosporine is absorbed through the gut wall into the bloodstream. It then enters T-lymphocytes — the white blood cells that orchestrate immune attacks. Inside these cells, cyclosporine binds to a protein called cyclophilin. The cyclosporine-cyclophilin complex then blocks an enzyme called calcineurin.

Calcineurin is essential because it activates a transcription factor called NFAT (Nuclear Factor of Activated T-cells). NFAT drives the production of interleukin-2 (IL-2), the key chemical signal that triggers T-cell activation and multiplication. By blocking calcineurin → NFAT → IL-2, cyclosporine effectively prevents T-cells from being activated and proliferating.

The result: the immune system's attack — whether on a transplanted organ or the body's own skin cells in psoriasis — is blunted. CYCLOPURE 100 delivers this mechanism in a reliable, bioavailable soft gelatin capsule designed by Steris Healthcare for consistent pharmacokinetic performance.

 

How to Take Cyclosporine 100 mg Capsule

Taking CYCLOPURE 100 correctly is critical to getting the right blood levels and minimising side effects. Follow your doctor's prescription exactly. Below are general evidence-based guidelines.

When Should I Take Cyclosporine 100 mg?

Cyclosporine 100 mg is typically taken twice daily — once in the morning and once in the evening, approximately 12 hours apart. Consistency is key: take it at the same time every day to maintain stable blood levels.

Blood level monitoring (trough levels, drawn just before your morning dose) is routinely used in transplant patients to ensure levels stay within the therapeutic window — high enough to prevent rejection, low enough to avoid toxicity.

Can Cyclosporine 100 mg Be Taken with Food?

Yes, CYCLOPURE 100 can be taken with or without food. However, consistency matters more than the presence of food. If you always take it with a meal, continue doing so — changing habits can affect absorption and alter blood levels.

Important dietary note: Avoid grapefruit and grapefruit juice while taking cyclosporine. Grapefruit inhibits CYP3A4 enzymes in the gut wall, which are responsible for metabolising cyclosporine. Eating grapefruit can sharply raise cyclosporine blood levels and increase toxicity risk.

High-fat meals may also increase absorption. Talk to your Steris Healthcare-prescribing physician about standardising your food intake during treatment.

What Happens If I Miss a Dose of Cyclosporine?

If you miss a dose of CYCLOPURE 100, take it as soon as you remember — unless it is close to the time of your next dose. In that case, skip the missed dose and resume your regular schedule. Never double up doses to make up for a missed one.

For transplant patients, missing doses is particularly serious and can precipitate acute rejection. If you repeatedly forget doses, discuss pill reminder strategies or blister-pack dispensing with your pharmacist.

 

Cyclosporine 100 mg Dosage for Adults

The correct dosage of cyclosporine 100 mg depends on body weight, indication, organ function, and blood level monitoring. Below are general starting dose ranges — your doctor will individualise this.

Indication	Typical Starting Dose
Kidney/liver/heart transplant	10–15 mg/kg/day in 2 divided doses
Psoriasis	2.5–5 mg/kg/day in 2 divided doses
Rheumatoid arthritis	2.5–4 mg/kg/day in 2 divided doses
Nephrotic syndrome	5 mg/kg/day in children; 2.5 mg/kg/day in adults

For a 60 kg adult with psoriasis on 3 mg/kg/day, this would mean 180 mg/day — so one CYCLOPURE 100 capsule twice daily with an additional adjustment.

Doses are titrated based on clinical response and cyclosporine blood trough levels. Steris Healthcare recommends all patients on CYCLOPURE 100 undergo regular kidney function tests (serum creatinine), blood pressure monitoring, and blood level checks as advised by their physician.

 

Cyclosporine 100 mg Side Effects

As with all immunosuppressants, cyclosporine 100 mg carries a risk of side effects. CYCLOPURE 100 users should be aware of these and report any concerning symptoms to their doctor promptly.

Common side effects (affecting more than 10% of users):

• Elevated blood pressure (hypertension)
• Kidney toxicity (nephrotoxicity) — evidenced by rising creatinine
• Tremor or hand shaking
• Excessive hair growth (hypertrichosis)
• Gum enlargement (gingival hyperplasia)
• Nausea or stomach upset

Less common but serious:

• Increased risk of infections (bacterial, viral, fungal)
• Elevated cholesterol and triglycerides
• Hyperkalemia (high potassium)
• Hypomagnesemia (low magnesium)
• Liver enzyme elevation

Rare but severe:

• Increased risk of lymphoma and skin cancers with long-term use
• Posterior reversible encephalopathy syndrome (PRES)
• Severe hypertension

Patients on CYCLOPURE 100 manufactured by Steris Healthcare should attend all follow-up appointments and never adjust the dose without physician guidance. Most side effects are dose-dependent and manageable with appropriate monitoring.

 

Precautions While Taking Cyclosporine

Before starting CYCLOPURE 100, inform your doctor about the following:

Medical history:

• Kidney or liver disease
• Hypertension or cardiovascular conditions
• History of cancer, especially skin cancer or lymphoma
• Active infections

Pregnancy and breastfeeding: Cyclosporine crosses the placenta and is detectable in breast milk. It should only be used in pregnancy if the benefit clearly outweighs the risk (e.g., post-transplant). Breastfeeding is not recommended.

Drug interactions to watch:

• NSAIDs (ibuprofen, diclofenac) — increase nephrotoxicity risk
• Potassium-sparing diuretics — worsen hyperkalemia
• Statins — risk of myopathy; dose adjustment may be needed
• Antifungals (fluconazole, ketoconazole) — increase cyclosporine levels
• Rifampicin, phenytoin — decrease cyclosporine levels
• Allopurinol, aminoglycosides — enhance kidney toxicity

Sun exposure: Cyclosporine increases skin cancer risk. Use SPF 50+ sunscreen and limit sun exposure. Never use a tanning bed while on CYCLOPURE 100.

Vaccinations: Live vaccines (MMR, varicella, yellow fever) are contraindicated during cyclosporine therapy. Inactivated vaccines are generally safe but may have reduced effectiveness.

 

Cyclosporine 100 mg for Dogs

Cyclosporine is not only used in human medicine — it is also FDA-approved for use in dogs under the brand name Atopica for canine atopic dermatitis (skin allergies). In veterinary medicine, cyclosporine 100 mg formulations are used in larger breed dogs for conditions including:

• Atopic dermatitis (chronic itching)
• Perianal fistulas
• Immune-mediated conditions post-organ transplant in research settings

However, it is critical to note that human formulations like CYCLOPURE 100 should not be used in animals without veterinary guidance. Veterinary-grade cyclosporine formulations are specifically dosed and formulated for dogs. Always consult a licensed veterinarian before giving your dog any cyclosporine product.

 

Cyclosporine vs Tacrolimus: Which Is Better?

Both cyclosporine and tacrolimus are calcineurin inhibitors widely used in transplant medicine and autoimmune disease. Here's how they compare:

Feature	Cyclosporine (CYCLOPURE 100)	Tacrolimus
Drug class	Calcineurin inhibitor	Calcineurin inhibitor
Binding protein	Cyclophilin	FKBP-12
Potency	Moderate	Higher (10–100× more potent)
Nephrotoxicity	Yes	Yes (slightly higher)
Hypertension	Common	Less common
Diabetes risk	Lower	Higher (new-onset diabetes)
Hair growth	Yes (hypertrichosis)	No
Hair loss	No	Yes (alopecia)
Gum overgrowth	Yes	Rare
Neurotoxicity	Lower	Higher
Cost	Generally lower	Generally higher
Use in psoriasis	Approved	Not standard

Which is better? There is no single answer — it depends on the patient, organ transplanted, risk factors, and tolerability. Tacrolimus is now preferred in most kidney and liver transplant protocols due to its superior efficacy in preventing rejection. However, cyclosporine remains the preferred choice in psoriasis, and for patients who develop diabetes or severe neurotoxicity on tacrolimus.

Steris Healthcare's CYCLOPURE 100 fills an important clinical and economic niche — providing reliable cyclosporine 100 mg capsule therapy at one of the best prices in India.

 

Cyclosporine 100 mg Price and Availability in India

One of the recurring questions from patients and caregivers is about cyclosporine 100 mg tablet price in India. Branded multinational cyclosporine products can be expensive, creating adherence challenges for patients on long-term therapy.

CYCLOPURE 100 by Steris Healthcare is positioned to address this gap. Steris Healthcare focuses on making quality immunosuppressants accessible to Indian patients without compromising on pharmaceutical standards. The cyclosporine 100 mg best price in India from Steris Healthcare makes CYCLOPURE 100 one of the most cost-effective cyclosporine 100 mg brands available.

Patients can purchase CYCLOPURE 100:

• Through hospital pharmacies (common for transplant patients)
• At retail pharmacies with a valid prescription
• Online via licensed pharmaceutical e-commerce platforms for cyclosporine 100 mg online purchase

Always ensure you are purchasing from a licensed pharmacy and that the product bears valid batch numbers, manufacturing date, and expiry date.

 

Conclusion

Cyclosporine 100 mg is a powerful immunosuppressant medicine mainly used to prevent organ transplant rejection and to manage certain autoimmune conditions. While it can be highly effective in controlling the immune response, it must always be taken under strict medical supervision due to its potential side effects and the need for regular monitoring. Proper use, dose adjustment, and follow-up with a healthcare professional are essential to ensure both safety and best treatment outcomes.

 

FAQs on Cyclosporine 100 mg

1. What is Cyclosporine 100 mg used for?

Cyclosporine 100 mg is used to prevent organ transplant rejection and treat autoimmune diseases like psoriasis, rheumatoid arthritis, and nephrotic syndrome.

2. Is Cyclosporine 100 mg a steroid?

No, Cyclosporine is not a steroid. It is a calcineurin inhibitor that suppresses specific immune cells (T-lymphocytes).

3. How long can Cyclosporine 100 mg be taken?

The duration depends on the condition. In psoriasis, it is usually used for short-term courses (12–16 weeks), while transplant patients may require long-term therapy under monitoring.

4. What are the major side effects of Cyclosporine?

Common side effects include:

• High blood pressure
• Kidney function changes
• Tremors
• Gum swelling
• Increased hair growth

5. Can Cyclosporine 100 mg be taken with food?

Yes, it can be taken with or without food, but consistency is important to maintain stable blood levels.

 

About Steris Healthcare

Steris Healthcare is an Indian pharmaceutical company committed to manufacturing high-quality, affordable specialty medicines. The company's focus on immunosuppressants, anti-infectives, and critical care medications reflects its mission to serve patients with complex, chronic conditions who need dependable treatment options.

CYCLOPURE 100 is one of Steris Healthcare's flagship formulations — a precision-dosed cyclosporine 100 mg soft gelatin capsule that combines pharmaceutical quality with price accessibility. Steris Healthcare operates under GMP-compliant manufacturing practices and is committed to supporting healthcare providers across India with science-backed, affordable therapy options.

For enquiries about CYCLOPURE 100 pricing, supply, or medical information, healthcare professionals and patients are encouraged to contact Steris Healthcare directly.