Benidipine + Metaprolol

Benidipine + Metaprolol

BENIPRIME M 50 is a combination medication containing Benidipine (4mg) and Metoprolol Succinate (50mg). This unique formulation is designed to effectively treat hypertension (high blood pressure) and angina (chest pain). Both Benidipine and Metoprolol Succinate work together to provide a powerful therapeutic effect by managing blood pressure and improving heart function. Benidipine is a calcium channel blocker, while Metoprolol Succinate is a beta-blocker. The combination of these two active ingredients helps to improve cardiovascular health, reduce the risk of heart attack, and promote long-term wellbeing.

Key Features and Ingredients

• Active Ingredients:

  • Benidipine (4mg):
    Benidipine is a calcium channel blocker that works by relaxing the blood vessels and reducing the resistance the heart has to pump against. This helps to lower blood pressure and reduce the workload on the heart, which can be particularly beneficial for individuals with hypertension or angina. It specifically targets L-type calcium channels, providing selective vasodilation with minimal reflex tachycardia.

  • Metoprolol Succinate (50mg):
    Metoprolol Succinate is a beta-blocker that reduces the effects of epinephrine (adrenaline) on the heart. It slows the heart rate, reduces the force of each contraction, and lowers blood pressure. It is commonly used to treat hypertension, angina, and heart failure, as well as to prevent heart attacks. In its succinate form, Metoprolol offers extended-release action, allowing for once-daily dosing.

• Dosage:
  Each tablet of BENIPRIME M 50 contains 4mg of Benidipine and 50mg of Metoprolol Succinate. The medication is typically taken once daily, but the exact dosage may be adjusted by a healthcare provider based on the patient’s specific needs and response to treatment.

Usage

BENIPRIME M 50 is used for the following conditions:

1. Hypertension (High Blood Pressure):
   BENIPRIME M 50 is primarily prescribed for the treatment of hypertension. High blood pressure puts extra strain on the heart and blood vessels, increasing the risk of heart disease, stroke, and kidney damage. By combining Benidipine, which relaxes blood vessels, and Metoprolol, which lowers heart rate and reduces cardiac output, BENIPRIME M 50 helps manage high blood pressure effectively.

2. Angina (Chest Pain):
   BENIPRIME M 50 can also be used to treat angina (chest pain), which occurs when the heart muscle does not receive enough oxygen-rich blood. Benidipine helps to dilate the coronary arteries, improving blood flow to the heart, while Metoprolol reduces the heart's demand for oxygen by lowering heart rate and contractility. This combination helps to alleviate angina symptoms and prevent future episodes.

3. Heart Failure (Off-label use):
   Metoprolol Succinate, an ingredient in BENIPRIME M 50, is often used off-label for managing heart failure by improving heart function and preventing the progression of the condition. The combination of Benidipine and Metoprolol may help reduce the strain on the heart in individuals with heart failure, offering relief and improving overall function.

Benefits of BENIPRIME M 50

1. Effective Blood Pressure Control:
   The combination of Benidipine and Metoprolol Succinate offers effective blood pressure control. Benidipine (4mg) works by relaxing and dilating blood vessels, while Metoprolol (50mg) reduces the heart's workload, resulting in a significant reduction in blood pressure. This helps prevent complications related to high blood pressure, such as stroke, heart attack, and kidney damage.

2. Relieves Angina Symptoms:
   For individuals with angina, BENIPRIME M 50 offers symptom relief by improving blood flow to the heart. Benidipine dilates the coronary arteries, while Metoprolol reduces the heart's oxygen demand, helping to reduce the frequency and intensity of angina attacks.

3. Improves Heart Function in Heart Failure:
   Metoprolol Succinate in BENIPRIME M 50 is known to improve heart function in patients with heart failure. It reduces the heart’s workload and helps prevent further heart damage. While Benidipine targets the blood vessels, both components work synergistically to improve overall cardiovascular health.

4. Long-Lasting Action:
   Thanks to the extended-release formulation of Metoprolol Succinate, BENIPRIME M 50 provides long-lasting blood pressure and heart rate control with a once-daily dose. This simplifies the medication regimen, improving patient compliance and ensuring consistent therapeutic effects throughout the day.

5. Prevents Cardiovascular Events:
   By controlling both blood pressure and heart rate, BENIPRIME M 50 helps to prevent major cardiovascular events, including heart attacks and strokes. The dual action of Benidipine and Metoprolol ensures that the heart is less stressed and better protected against damage.

Key Considerations

• Side Effects:
  While BENIPRIME M 50 is generally well-tolerated, some individuals may experience side effects. Common side effects include dizziness, fatigue, slow heart rate (bradycardia), or low blood pressure. More serious side effects such as shortness of breath, swelling in the legs, or extreme fatigue may occur, especially in individuals with heart failure. If any of these occur, patients should contact their healthcare provider immediately.

• Drug Interactions:
  BENIPRIME M 50 can interact with other medications, especially those that affect blood pressure, heart rate, or electrolyte balance. For example, other calcium channel blockers, antihypertensive drugs, or antiarrhythmic medications may amplify the effects of Benidipine or Metoprolol. Patients should inform their healthcare provider about all medications they are currently taking.

• Precautions:
  BENIPRIME M 50 should be used with caution in patients with a history of bradycardia, heart block, or severe liver impairment. The medication may need dose adjustments for such individuals. Pregnant or breastfeeding women should also consult a doctor before starting this medication.

Conclusion

BENIPRIME M 50, with its combination of Benidipine (4mg) and Metoprolol Succinate (50mg), is a highly effective medication for managing hypertension and angina. The synergistic action of Benidipine, a calcium channel blocker, and Metoprolol, a beta-blocker, helps to regulate blood pressure, improve heart function, and alleviate chest pain. With its extended-release formulation, BENIPRIME M 50 offers long-lasting control and convenience, ensuring improved outcomes for patients. However, as with any medication, it is crucial to use BENIPRIME M 50 under the guidance of a healthcare provider, who can monitor for any side effects or drug interactions, ensuring the treatment is both safe and effective. Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options. The company offers a wide range of healthcare products, catering to various medical needs, from rare disease treatments to essential healthcare products. Sterispharma's product range includes solutions for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. Medicines can be conveniently ordered via Our websites—Sterisonline, Sterisindia, and Sterispharma.

For further information 

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