Sacubitril Valsartan tablets – Uses, Benefits & Side Effects Explained

When it comes to managing heart failure or high blood pressure, early and effective treatment is essential. Whether you're just starting therapy or require a low-dose option to maintain heart health, Sacubitril (12 mg), Valsartan (13 mg) provides a well-balanced solution for patients needing a gentle yet effective approach. This combination is available as SACUSMART 25, a trusted brand from Steris Healthcare, formulated to support your heart health from the very first step.

In this blog, we'll explore the uses, benefits, dosage, mechanism of action, and more about Sacubitril (12 mg), Valsartan (13 mg) tablets. Designed for patients and caregivers, this guide also explains why SACUSMART 25 is the smart choice for beginning or continuing heart failure management.

What is Sacubitril (12 mg), Valsartan (13 mg)?

Sacubitril (12 mg), Valsartan (13 mg) is a low-dose combination medication used for the treatment of chronic heart failure and hypertension (high blood pressure). It belongs to a class of medicines known as angiotensin receptor-neprilysin inhibitors (ARNIs) and is often used in patients who are just starting heart failure therapy or those requiring a milder dose.

You will find this combination under the brand name SACUSMART 25 from Steris Healthcare, designed for high tolerability and long-term effectiveness. The dual mechanism of sacubitril-valsartan makes it a preferred option for heart failure management worldwide.

Uses of Sacubitril (12 mg), Valsartan (13 mg)

This medication is primarily prescribed for:

• Chronic Heart Failure with Reduced Ejection Fraction (HFrEF)
  It helps improve the heart’s ability to pump blood, reduces the risk of hospitalization, and can extend life expectancy in patients with heart failure.

• High Blood Pressure (Hypertension)
  By lowering blood pressure, Sacubitril (12 mg), Valsartan (13 mg) reduces the risk of stroke, heart attack, and other cardiovascular events.

Tab Sacubitril Valsartan uses are growing in both primary and maintenance therapy for heart failure due to its effectiveness and patient-friendly dosage profile.

How Sacubitril and Valsartan Work (Mechanism of Action)

The power of Sacubitril-valsartan lies in its dual-action mechanism:

• Sacubitril (12 mg): Inhibits the neprilysin enzyme, which normally breaks down beneficial peptides like BNP (brain natriuretic peptide). These peptides help relax blood vessels, reduce sodium retention, and lower blood pressure.

• Valsartan (13 mg): Blocks the angiotensin II receptor, preventing blood vessel constriction and reducing blood pressure. It also lowers the workload on the heart.

Together, this combo improves heart efficiency, controls fluid build-up, and enhances overall cardiovascular health.

Dosage of SACUSMART 25

SACUSMART 25 is usually prescribed as an initial or maintenance dose:

• Typical dose: One tablet of Sacubitril (12 mg), Valsartan (13 mg) once or twice daily, depending on your doctor's recommendation.

• Titration: For many patients, the dose may be gradually increased based on tolerance and clinical response.

Always follow your healthcare provider's guidance. Do not self-adjust your dose.

Side Effects of Sacubitril-Valsartan Tablets

While Sacubitril (12 mg), Valsartan (13 mg) is generally well-tolerated, like all medications, it may cause side effects in some patients:

Common Side Effects:

• Dizziness or lightheadedness

• Cough

• Tiredness or fatigue

• Low blood pressure

Serious Side Effects:

• Swelling of the face, lips, or tongue (sign of angioedema)

• High potassium levels (hyperkalemia)

• Kidney function decline

• Difficulty breathing

If you experience any serious side effects, consult your doctor immediately.

Who Should Avoid SACUSMART 25?

• Patients with a history of angioedema

• Pregnant women (can harm the unborn baby)

• Individuals with severe kidney or liver impairment

• Those currently on ACE inhibitors (a washout period is required)

Always inform your healthcare provider about all medications and supplements you're taking.

Why Choose SACUSMART 25 by Steris Healthcare?

When selecting a treatment for heart failure or hypertension, quality and trust matter. Here’s why SACUSMART 25 by Steris Healthcare is a preferred option:

• High-quality and internationally certified manufacturing
• Affordable pricing for long-term therapy
• Wide availability across India
• Research-based formulations focused on patient health and safety

Frequently Asked Questions

1. What is Sacubitril (12 mg), Valsartan (13 mg) used for?

It is used to treat heart failure and high blood pressure by improving blood circulation, lowering blood pressure, and helping the heart pump more efficiently.

2. Is SACUSMART 25 suitable for long-term use?

Yes. It is often prescribed for long-term use in managing chronic heart failure. Your doctor will monitor your response to the treatment over time.

3. Can I take this with other heart medications?

In many cases, yes. However, combinations with ACE inhibitors, potassium supplements, or NSAIDs may need monitoring or adjustments. Always check with your doctor.

4. What should I do if I miss a dose?

Take it as soon as you remember. If it’s close to the next dose, skip the missed one. Do not double up.

5. Is SACUSMART 25 safe during pregnancy?

No. It is not recommended during pregnancy as it can harm the unborn baby. Inform your doctor if you’re planning to conceive.

Final Thoughts

Managing heart failure or hypertension doesn’t have to be overwhelming. With the right treatment and guidance, it’s possible to improve your heart health and overall well-being. SACUSMART 25, containing Sacubitril (12 mg), Valsartan (13 mg), offers a trusted, low-dose therapy designed for early management, maintenance therapy, or dose-sensitive patients.

Let Steris Healthcare be your partner in care—bringing you reliable, patient-focused cardiac solutions that truly make a difference.