Learn about Sacubitril 49mg and Valsartan 51mg Tablets (SACUSMART 100) for heart failure management. Explore uses, dosage, benefits, precautions, side effects, and why patients trust Steris Healthcare.
Sep 20, 2025
If you or a loved one is living with heart failure or hypertension, managing these conditions effectively is key to improving long-term health and well-being. One such treatment that has gained recognition in the medical community is SACUSMART 100, a combination tablet containing Sacubitril 49mg and Valsartan 51mg. In this blog, we will explore the benefits, uses, and essential details of Sacubitril 49mg and Valsartan 51mg tablets, as well as why choosing SACUSMART 100 from Steris Healthcare is a decision that could make a positive difference in your health journey.
What Are Sacubitril 49mg and Valsartan 51mg Tablets?
SACUSMART 100 is a combination medication consisting of Sacubitril 49mg and Valsartan 51mg. These two active ingredients work together to help manage chronic heart failure (CHF) and high blood pressure, conditions that often go hand in hand.
-
Sacubitril 49mg: This component of the tablet inhibits the enzyme neprilysin, which breaks down naturally occurring peptides that help regulate blood pressure and reduce fluid retention. By blocking this enzyme, Sacubitril helps dilate blood vessels and reduce fluid buildup around the heart, easing the strain on the heart.
-
Valsartan 51mg: As an angiotensin II receptor blocker (ARB), Valsartan helps lower blood pressure by relaxing blood vessels and preventing the constriction that can cause high blood pressure and strain on the heart.
Together, Sacubitril 49mg and Valsartan 51mg tablets offer a dual-action therapy that helps improve heart function, reduce symptoms of heart failure, and lower blood pressure in patients who require a comprehensive treatment plan.
Key Benefits of Sacubitril and Valsartan Tablets
-
Heart Failure Symptom Relief: By relaxing blood vessels and reducing fluid retention, SACUSMART 100 helps alleviate common symptoms of heart failure, such as breathlessness, fatigue, and swelling.
-
Effective Blood Pressure Management: The Sacubitril 49mg and Valsartan 51mg tablets work together to control high blood pressure, lowering the risk of stroke, heart attack, and kidney failure, all of which are common complications of uncontrolled hypertension.
-
Improved Long-Term Outcomes: Long-term use of Sacubitril valsartan tablets has been shown to improve overall cardiovascular health and enhance long-term outcomes for patients suffering from heart failure and hypertension.
-
Reduced Risk of Death: Research has demonstrated that the combination of Sacubitril 49mg + Valsartan 51mg significantly reduces the risk of death from cardiovascular causes in patients with heart failure, making it an essential part of heart failure management.
Uses of SACUSMART 100 (Sacubitril 49mg and Valsartan 51mg Tablets)
SACUSMART 100 is primarily used in the treatment and management of the following conditions:
-
Chronic Heart Failure (CHF):
-
SACUSMART 100 is prescribed to reduce the risk of hospitalization and cardiovascular death in patients with chronic heart failure, particularly those with reduced ejection fraction (HFrEF). It improves the heart’s ability to pump blood efficiently, alleviating symptoms such as fatigue, shortness of breath, and fluid retention.
-
-
Hypertension (High Blood Pressure):
-
By relaxing blood vessels, SACUSMART 100 helps lower high blood pressure, reducing the risk of complications such as stroke, heart attack, and kidney damage. It is an effective treatment for individuals who struggle with uncontrolled hypertension.
-
Mechanism of Action of Sacubitril and Valsartan Tablets
SACUSMART 100 works through a combination of two powerful mechanisms:
-
Sacubitril (49mg):
-
Sacubitril inhibits neprilysin, an enzyme that breaks down natriuretic peptides. These peptides play a crucial role in lowering blood pressure, relaxing blood vessels, and eliminating excess sodium and water from the body. By preventing the breakdown of these peptides, Sacubitril helps to dilate blood vessels and reduce fluid retention, easing the workload on the heart.
-
-
Valsartan (51mg):
-
Valsartan is an angiotensin II receptor blocker (ARB). Angiotensin II is a hormone that constricts blood vessels, leading to increased blood pressure. By blocking the action of this hormone, Valsartan helps relax blood vessels, improving blood flow and lowering blood pressure.
-
Together, these two drugs work synergistically to improve heart function, reduce fluid buildup, and control blood pressure, providing comprehensive relief from symptoms of heart failure and hypertension.
Dosage of SACUSMART 100 (Sacubitril 49mg and Valsartan 51mg Tablets)
SACUSMART 100 is usually prescribed as part of a long-term treatment plan for chronic heart failure or hypertension. The typical dosage for adults is as follows:
-
Starting Dose: The usual starting dose is one tablet (SACUSMART 100) taken once a day.
-
Maintenance Dose: Depending on your response to treatment, your healthcare provider may adjust your dosage to a higher dose over time. This is typically done after a few weeks of initial therapy.
It’s essential to follow your doctor’s recommendations regarding dosage and frequency. Never alter your dosage or discontinue the medication without consulting your healthcare provider.
Side Effects of Sacubitril and Valsartan Tablets
Like any medication, SACUSMART 100 can cause side effects in some individuals. The side effects range from mild to severe and may include the following:
Common Side Effects:
-
Dizziness or light-headedness, particularly when standing up quickly.
-
Fatigue or tiredness.
-
Headache.
-
Cough, particularly a dry cough due to the effects of Valsartan.
Serious Side Effects:
-
Swelling (especially of the face, lips, or tongue), which may indicate an allergic reaction.
-
Difficulty breathing, a serious sign of an allergic reaction or other issues.
-
Low blood pressure (hypotension), which may cause dizziness, fainting, or weakness.
-
Kidney problems, such as reduced urine output or swelling in the legs and feet, can occur, especially in patients with pre-existing kidney conditions.
-
Elevated potassium levels (hyperkalemia), which may lead to irregular heartbeats, muscle weakness, or paralysis.
If you experience any of these serious side effects, contact your healthcare provider immediately. In some cases, your doctor may adjust your treatment plan or recommend an alternative therapy.
Precautions:
-
Pregnancy: SACUSMART 100 is not recommended during pregnancy, especially in the second and third trimesters, as it can harm the fetus.
-
Kidney Issues: Individuals with severe kidney problems should inform their healthcare provider, as dose adjustments may be necessary.
-
Angioedema Risk: This medication may cause angioedema (swelling beneath the skin), particularly in people with a history of allergic reactions to ARBs or ACE inhibitors.
Why Choose Steris Healthcare for SACUSMART 100?
Steris Healthcare is committed to providing high-quality, safe, and affordable medicines. SACUSMART 100 (Sacubitril 49mg + Valsartan 51mg Tablets) is manufactured under WHO-GMP certified facilities, ensuring quality and reliability.
Patients and doctors trust Steris Healthcare because:
-
Strict adherence to international quality standards
-
Affordable long-term treatment options
-
Wide availability across India
-
Focus on patient health and safety
Frequently Asked Questions
-
What is sacubitril 49mg and valsartan 51mg tablets used for?
It is used to treat heart failure by improving heart function and reducing symptoms. -
Can I take SACUSMART 100 with other heart medications?
You should consult your doctor before combining with other drugs to avoid interactions. -
How quickly do sacubitril and valsartan tablets work?
Most patients notice improvement within a few weeks, but consistent use is essential. -
Are there any dietary restrictions while on this medication?
Avoid high potassium foods or salt substitutes unless advised by your healthcare provider. -
What should I do if I miss a dose of SACUSMART 100?
Take it as soon as you remember, but skip if it’s near the time for your next dose. Do not double dose.
Conclusion
Sacubitril 49mg Valsartan 51mg tab is a reliable solution for patients living with chronic heart failure. It improves heart function, reduces hospitalization risk, and enhances quality of life.
If you or your loved ones are managing heart failure, consult your doctor today about SACUSMART 100 by Steris Healthcare – a trusted choice for effective heart care.
Recent Post

Sacubitril Valsartan tablets – Uses, Benefits & Side Effects Explained

sacubitril and valsartan tablets uses in hindi - डोज़, साइड इफेक्ट्स और सावधानियाँ

Sacubitril 97mg and Valsartan 103mg Tablets – Benefits, Dosage & Side Effects

Sacubitril 24mg and Valsartan 26mg Tablets – Benefits, Uses & Side Effects Explained

Sacubitril and Valsartan Tablets – Uses, Benefits & Side Effects

Sacubitril Valsartan Tablets Uses, Benefits & Side Effects

Lonicazole Cream: Uses, Benefits and FAQ

Cinacalcet 30 mg Uses, Dosage, Side Effects & Structure

Cyclosporine 100 mg: Uses, Side Effects & Precautions

Cyclosporine 50 mg – Uses, Side Effects & Dosage