S PHYLLIN DX (Acebrophylline (100mg) & Doxofylline (400mg)):Uses, Benefits, Dosage, Price, Side Effects and other information..... ..

Jul 29, 2024

Introduction

S PHYLLIN DX is a powerful combination respiratory medicine containing Acebrophylline 100 mg and Doxofylline 400 mg, specifically formulated for the treatment of chronic respiratory conditions like asthma, chronic bronchitis, and chronic obstructive pulmonary disease (COPD). This dual-action formula helps open the airways, reduce inflammation, and improve breathing comfort in both acute and maintenance phases of treatment.

Composition:

  • Acebrophylline – 100 mg

  • Doxofylline – 400 mg

  • Brand Name: S PHYLLIN DX

  • Dosage Form: Oral Tablet

What is S PHYLLIN DX?

S PHYLLIN DX is a fixed-dose combination of two bronchodilators with complementary mechanisms:

  • Acebrophylline 100 mg is a mucolytic and bronchodilator that enhances mucus clearance while relaxing bronchial muscles.

  • Doxofylline 400 mg is a xanthine derivative that relaxes airway muscles and improves lung airflow with minimal cardiac stimulation compared to theophylline.

Together, these agents offer enhanced anti-inflammatory, mucolytic, and bronchodilatory effects—ideal for managing obstructive pulmonary diseases.

S PHYLLIN DX Uses:

This combination is effective for:

Acebrophylline 100 mg Uses:

  • Loosens thick mucus in the lungs

  • Reduces airway inflammation

  • Aids in smooth breathing by relaxing bronchial muscles

Doxofylline 400 mg Uses:

  • Acts as a bronchodilator to ease airway constriction

  • Manages bronchial asthma and COPD

  • Provides a safer alternative to theophylline with fewer cardiac side effects

Mechanism of Action:

  • Acebrophylline: Combines ambroxol’s mucolytic effects with bronchodilation through inhibition of phosphodiesterase enzymes and cytokine modulation.

  • Doxofylline: Inhibits phosphodiesterase (PDE) enzymes, increasing intracellular cAMP, which causes bronchial smooth muscle relaxation without the cardiotoxicity associated with traditional xanthines.

Doxofylline 400 mg Dosage:

  • Adults: Usually 1 tablet twice daily, or as directed by a physician.

  • Dosage may vary based on clinical severity and patient response.

Note: Avoid exceeding prescribed dose; always consult your doctor.

Doxofylline 400 mg Side Effects:

Common Side Effects:

  • Nausea

  • Vomiting

  • Headache

  • Gastric discomfort

  • Insomnia

Rare but Serious Side Effects:

  • Palpitations

  • Muscle tremors

  • Nervousness

  • Hypotension

  • Allergic reactions

These side effects are rare and often dose-related.

Precautions & Warnings:

  • Not suitable for patients with severe liver or kidney disease

  • Use caution in elderly patients or those with heart disorders

  • Avoid alcohol and smoking during treatment

  • Pregnancy & Breastfeeding: Use only if clearly needed and under supervision

Drug Interactions:

  • May interact with antibiotics like erythromycin or ciprofloxacin

  • Caution with beta-agonists, corticosteroids, and other bronchodilators

  • Avoid concurrent use with other xanthines

FAQs – S PHYLLIN DX (Acebrophylline 100 mg + Doxofylline 400 mg)

Q1. What is S PHYLLIN DX used for?

A: It is used to treat chronic respiratory conditions like asthma, COPD, and chronic bronchitis by improving airflow and reducing mucus.

Q2. Is S PHYLLIN DX safe for long-term use?

A: Yes, under medical supervision, it can be safely used for long-term management of chronic lung conditions.

Q3. What are the side effects of doxofylline 400 mg?

A: Side effects are generally mild and include nausea, headache, or gastric discomfort. Serious effects are rare.

Q4. Can I use S PHYLLIN DX for acute asthma attacks?

A: It is more suitable for maintenance therapy. In acute attacks, use a fast-acting bronchodilator as prescribed.

Q5. How does acebrophylline 100 mg work?

A: It helps break down mucus and relaxes airway muscles, reducing inflammation and easing breathing.

Conclusion:

S PHYLLIN DX is a superior respiratory solution for patients struggling with obstructive airway diseases. With the dual action of Acebrophylline 100 mg and Doxofylline 400 mg, it offers powerful symptom relief, better mucus clearance, and smoother breathing—without the high risk of cardiac side effects. Ideal for long-term maintenance in chronic bronchitis, asthma, and COPD patients.

About The Company

Steris Healthcare Pvt Ltd, widely recognized as Sterispharma, was established in February 2018 by a team of seasoned experts from the pharmaceutical sector. Based in Navi Mumbai, the company is proudly certified by WHO, GMP, and ISO, underscoring its unwavering commitment to quality and patient safety. Sterispharma is driven by a mission to make affordable, premium-quality medicines accessible throughout India, adhering strictly to WHO-recommended standards. Through its user-friendly online pharmacy platforms, customers can effortlessly order medications with home delivery services.

Sterispharma boasts an extensive portfolio of healthcare solutions, ranging from treatments for rare diseases to essential everyday healthcare needs. Their comprehensive product lineup addresses multiple therapeutic areas including Cardiology, Asthma, Respiratory Disorders, Nasal Care, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infective/Antibiotic Therapy, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. Medications are easily available for online purchase through their official websites — Sterisonline, Sterisindia, and Sterispharma — offering a seamless and reliable healthcare experience.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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