NAPROXZEN D 500: Effective Pain Management with GI Safety

NAPROXZEN D 500, featuring Naproxen (500mg) and Domperidone (10mg), delivers powerful dual-action relief for migraines, arthritis pain, menstrual cramps, and inflammatory conditions. This Steris Healthcare product combines NSAID potency with antiemetic protection, preventing nausea while targeting pain and swelling effectively.​

Ideal for patients seeking comprehensive symptom management, NAPROXZEN D 500 ensures faster recovery, improved mobility, and better quality of life without gastric upset.​

What is NAPROXZEN D 500?

NAPROXZEN D 500 from Steris Healthcare is a film-coated tablet blending high-strength Naproxen (500mg), a non-steroidal anti-inflammatory drug (NSAID), with Domperidone (10mg), a prokinetic antiemetic.​

• Naproxen inhibits COX enzymes to block prostaglandin synthesis, reducing pain, fever, and inflammation.​

• Domperidone enhances gastric motility and blocks dopamine receptors in the brain's vomiting center.​

• Manufactured under GMP standards at Steris Healthcare for consistent quality and bioavailability.​

This formulation outperforms single-agent therapies by addressing both pain and associated nausea.​

Composition of NAPROXZEN D 500

The core strength of NAPROXZEN D 500 lies in its precise composition: Naproxen 500mg provides long-lasting anti-inflammatory effects, while Domperidone 10mg safeguards against GI side effects.​

Active Ingredients Breakdown

• Naproxen (500mg): Propionic acid derivative NSAID with prolonged half-life (12-17 hours) for once/twice-daily dosing.​

• Domperidone (10mg): Dopamine D2 antagonist that accelerates stomach emptying without crossing blood-brain barrier significantly.​

Inactive Components

• Excipients like microcrystalline cellulose, magnesium stearate, and coating agents ensure smooth disintegration and absorption.​

Steris Healthcare optimizes this blend for superior tolerability over generic alternatives.​

Uses of NAPROXZEN D 500

NAPROXZEN D 500 treats moderate to severe pain from migraines, rheumatoid arthritis, osteoarthritis, gout, dysmenorrhea, muscle strains, and post-surgical recovery.​

• Migraine management: Relieves headache pain and prevents nausea/vomiting.​

• Musculoskeletal disorders: Reduces joint swelling and stiffness in arthritis.​

• Menstrual pain: Eases cramps and backache with anti-inflammatory action.​

• Dental/postoperative pain: Controls acute inflammation and fever.​

Versatile for acute and chronic conditions, making it a Steris Healthcare staple.​

How NAPROXZEN D 500 Works

Naproxen in NAPROXZEN D 500 selectively inhibits COX-1/COX-2 enzymes, decreasing prostaglandin production that triggers pain and inflammation.​

Dual Mechanism Details

• Domperidone stimulates peristalsis via 5-HT4 agonism and blocks CTZ dopamine receptors to curb nausea.​

• Synergy: Pain relief without emetic side effects, with peak effects in 1-2 hours and duration up to 12 hours.​

• Improves gastric emptying, countering NSAID-induced delays.​

This targeted approach provides quicker, sustained relief than naproxen alone.​

Benefits of NAPROXZEN D 500

Patients experience rapid pain reduction, reduced inflammation, and nausea prevention, enhancing daily function and recovery speed.​

• Long-acting formula minimizes dosing frequency for better adherence.

• Protects stomach lining, ideal for long-term arthritis use.

• Effective in migraine clusters with vomiting predisposition.​

• Cost-effective from Steris Healthcare with proven efficacy.​

Dosage and Administration for NAPROXZEN D 500

Initial dose: 1 tablet (Naproxen 500mg + Domperidone 10mg) twice daily after meals; max 2 tablets/day for adults.​

Guidelines by Condition

• Migraine/Acute Pain: 1 tablet at onset, repeat after 8-12 hours if needed.

• Arthritis/Chronic: 1 tablet BID, taper per response.​

• Swallow whole with water; avoid in children under 12.​

Monitor response; consult Steris Healthcare physicians for adjustments.​

Side Effects of NAPROXZEN D 500

Mild effects include drowsiness, dry mouth, dyspepsia; serious risks like GI bleed rare with short-term use.​

Precautions and Warnings

Avoid in peptic ulcer, severe liver/kidney disease, pregnancy (3rd trimester), or hypersensitivity.​

• Caution in elderly, asthmatics, or cardiac patients.

• Monitor for bleeding signs; hydrate adequately.​

• Not for long-term without supervision.​

Steris Healthcare advises regular check-ups.

Drug Interactions

NAPROXZEN D 500 potentiates anticoagulants, increases lithium levels; avoid with ketoconazole or anticholinergics.​

• NSAIDs/aspirin: Enhanced GI risk.

• Antihypertensives: Possible BP elevation.​

Full list via Steris Healthcare pharmacist.​

NAPROXZEN D 500 for Specific Conditions

Migraine Relief

Targets headache and vomiting for cluster attacks.​

Arthritis Management

Reduces flare-ups, improves joint function.​

Menstrual Cramps

Eases dysmenorrhea with minimal bloating.​

Patient Testimonials on NAPROXZEN D 500

Users praise quick migraine relief without vomiting, better arthritis mobility.​

Lifestyle Tips with NAPROXZEN D 500

• Pair with balanced diet, hydration, stress management.

• Avoid alcohol; use heat therapy for muscles.​

Storage Instructions

Store at room temperature (15-30°C), away from moisture; Steris Healthcare shelf life: 24 months.​

Why Choose NAPROXZEN D 500 from Steris Healthcare?

Premium quality, dual benefits, affordable pricing for Indian market leadership.​

Company Spotlight: Steris Healthcare

Steris Healthcare leads in innovative pharmaceuticals, ensuring NAPROXZEN D 500 meets global standards for pain management.​

Frequently Asked Questions (FAQs)

1. What is NAPROXZEN D 500 used for?

Relieves migraines, arthritis, menstrual pain with nausea prevention.​

2. How quickly does NAPROXZEN D 500 work?

Pain relief in 30-60 minutes; anti-nausea faster.​

3. Can I take NAPROXZEN D 500 daily?

Short-term yes; chronic use under doctor guidance.​

4. Is NAPROXZEN D 500 safe for stomach?

Domperidone reduces risks; take post-meal.​

5. NAPROXZEN D 500 during pregnancy?

Avoid, especially later trimesters.​

6. Dosage for arthritis pain?

1 tablet BID; max 1000mg naproxen/day.​

7. Side effects of long-term use?

GI issues possible; monitor liver/kidney.​

8. Buy NAPROXZEN D 500 online?

Available via Steris Healthcare portals.​

9. Alternatives to NAPROXZEN D 500?

Consult for ibuprofen combos; less effective.​

10. NAPROXZEN D 500 for dental pain?

Yes, effective for inflammation.

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