Mesalamine Delayed 1200 mg

MESALMILE OD: Mesalamine PR (1200mg) – Complete Overview

MESALMILE OD is a medication that contains Mesalamine (1200mg) as its active ingredient. It is an extended-release formulation of Mesalamine, a 5-aminosalicylic acid (5-ASA) compound used to treat inflammatory bowel diseases (IBD) such as Ulcerative Colitis and Crohn's Disease. MESALMILE OD is specifically designed for patients with moderate to severe forms of these conditions, helping to reduce inflammation in the intestines and manage symptoms effectively.

What is MESALMILE OD?

MESALMILE OD is a Mesalamine-based oral medication in the form of an extended-release tablet. Each tablet contains 1200mg of Mesalamine, which works directly on the gut to reduce inflammation, soothe irritation, and control symptoms associated with Ulcerative Colitis and Crohn's Disease. The OD (Once Daily) designation indicates that the medication is typically taken once a day, thanks to its extended-release properties.

Key Features and Ingredients

• Active Ingredient: Mesalamine (1200mg) is the active ingredient in MESALMILE OD, which belongs to the class of drugs known as 5-aminosalicylic acid (5-ASA). It works by targeting inflammation in the lining of the intestines.

• Mechanism of Action: Mesalamine works locally in the intestine to reduce inflammation by inhibiting the production of inflammatory chemicals called prostaglandins. This helps decrease symptoms such as pain, diarrhea, and rectal bleeding commonly associated with inflammatory bowel diseases.

• Formulation: MESALMILE OD comes in an extended-release tablet form, allowing for the slow release of Mesalamine over time, making it effective for 24-hour symptom control.

Uses of MESALMILE OD

MESALMILE OD is primarily prescribed for the following conditions:

1. Ulcerative Colitis:

   • Ulcerative Colitis is an inflammatory bowel disease (IBD) that causes long-term inflammation and ulcers in the inner lining of the large intestine (colon). Mesalamine helps to control the inflammation, reducing symptoms such as abdominal pain, diarrhea, and bleeding.

2. Crohn's Disease:

   • Crohn’s Disease is another form of IBD that can affect any part of the gastrointestinal tract, from the mouth to the anus. Mesalamine helps to reduce inflammation in the intestines, promoting healing and improving the symptoms of Crohn's Disease.

3. Maintenance of Remission:

   • MESALMILE OD can be used to maintain remission in patients who have responded to initial treatment for Ulcerative Colitis or Crohn’s Disease, helping to prevent relapse of symptoms.

How Does MESALMILE OD Work?

The active ingredient, Mesalamine, is an anti-inflammatory drug that works directly in the intestines by:

1. Inhibiting Inflammatory Enzymes: Mesalamine inhibits the cyclooxygenase (COX) enzymes in the intestines that produce prostaglandins, which are chemicals that cause inflammation. By reducing prostaglandin production, Mesalamine helps decrease inflammation in the gut.

2. Local Action in the Gut: Since Mesalamine is not absorbed significantly into the bloodstream, it works directly in the intestines, where it is needed most. The extended-release formulation ensures that Mesalamine is gradually released throughout the day, providing long-lasting symptom relief.

3. Reduction of Ulcers and Inflammation: By controlling the inflammation in the intestines, Mesalamine helps to prevent the formation of ulcers and promotes healing of the intestinal lining.

Benefits of MESALMILE OD

1. Effective Control of Symptoms:

   • MESALMILE OD provides significant relief from the symptoms of Ulcerative Colitis and Crohn’s Disease, including abdominal pain, diarrhea, blood in stool, and urgency. It helps reduce flare-ups and prevent long-term complications.

2. Long-Lasting Relief:

   • The extended-release formulation of MESALMILE OD ensures that the active ingredient is gradually released, providing relief for up to 24 hours with just one dose per day. This makes it more convenient for patients compared to medications that require multiple doses.

3. Reduction in Intestinal Inflammation:

   • Mesalamine reduces the inflammation in the intestines, which is the root cause of many symptoms in inflammatory bowel diseases like Ulcerative Colitis and Crohn’s Disease.

4. Prevention of Disease Relapse:

   • MESALMILE OD is also used as a maintenance therapy to prevent the recurrence of symptoms in patients who have achieved remission, helping to keep the disease under control over the long term.

5. Safe for Long-Term Use:

   • Mesalamine is generally well-tolerated, making it suitable for long-term use in patients with chronic conditions such as Ulcerative Colitis and Crohn’s Disease.

How to Use MESALMILE OD

• Dosage: The typical recommended dose of MESALMILE OD is 1200mg once daily, though the exact dosage may vary based on your condition and your doctor’s recommendations. Always follow your healthcare provider's instructions for the correct dosage.

• Administration: Take MESALMILE OD tablets orally with a full glass of water. It is usually taken once daily in the morning or evening, with or without food. Do not crush or chew the tablets, as this may affect the way the medication works.

• Consistency: For best results, take MESALMILE OD at the same time every day. Consistency is important in managing the symptoms of inflammatory bowel disease and maintaining remission.

• Monitoring: Regular follow-up visits to your healthcare provider are essential to monitor the effectiveness of the treatment and any potential side effects.

Possible Side Effects of MESALMILE OD

While MESALMILE OD is generally well-tolerated, some patients may experience side effects, including:

1. Gastrointestinal Issues:

   • Abdominal pain, bloating, diarrhea, or nausea are common, especially during the early stages of treatment.

2. Headache:

   • Some patients may experience mild to moderate headaches.

3. Rash:

   • Skin rashes can occasionally occur with Mesalamine treatment.

4. Elevated Liver Enzymes:

   • In rare cases, Mesalamine may cause liver dysfunction, which can be monitored through blood tests.

5. Allergic Reactions:

   • In some cases, patients may experience allergic reactions, including rash, itching, and difficulty breathing. Contact your doctor immediately if you experience any signs of an allergic reaction.

6. Blood Disorders:

   • Though rare, Mesalamine may affect blood cell counts, leading to conditions like anemia or thrombocytopenia (low platelet count).

Precautions and Warnings

1. Allergies to Sulfa Drugs:

   • If you have a known allergy to sulfa-based medications, you should inform your healthcare provider before using Mesalamine.

2. Renal and Hepatic Impairment:

   • Patients with kidney or liver problems should use MESALMILE OD with caution and may require closer monitoring during treatment.

3. Pregnancy and Breastfeeding:

   • Mesalamine is considered safe during pregnancy, but it should only be used if absolutely necessary. Consult your doctor before taking MESALMILE OD if you are pregnant or breastfeeding.

4. Interactions with Other Medications:

   • MESALMILE OD may interact with other medications, particularly those that affect liver or kidney function. Always inform your healthcare provider about any other medications you are currently taking.

FAQ Section

Q1: What is MESALMILE OD used for?
MESALMILE OD is used to treat Ulcerative Colitis and Crohn’s Disease by reducing inflammation in the intestines. It can also be used to maintain remission in patients with these conditions.

Q2: How should I take MESALMILE OD?
Take MESALMILE OD once daily, with or without food. Swallow the tablet whole with a full glass of water. Do not chew or crush the tablet.

Q3: How long does it take for MESALMILE OD to work?
It may take a few weeks to see significant improvement in symptoms such as abdominal pain and diarrhea. Full benefits are typically observed within 4 to 6 weeks.

Q4: Can I stop taking MESALMILE OD once I feel better?
Do not stop taking MESALMILE OD without consulting your healthcare provider, as stopping treatment prematurely may lead to a relapse of symptoms.

Q5: What should I do if I miss a dose of MESALMILE OD?
If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and take your next dose at the usual time. Do not take two doses at once.

Conclusion

MESALMILE OD (Mesalamine 1200mg) is an effective medication for managing Ulcerative Colitis and Crohn's Disease. By reducing intestinal inflammation, it helps alleviate symptoms, promote healing, and maintain remission. With its extended-release formulation, MESALMILE OD offers convenient once-daily dosing. Always follow your healthcare provider's instructions for optimal results and safety.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

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