Apixaban

Introduction

APIXAZEN 2.5 is a prescription medication that contains Apixaban (2.5mg), an anticoagulant belonging to the class of direct factor Xa inhibitors. It is commonly prescribed to prevent and treat blood clots, reducing the risk of serious conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), and stroke in patients with atrial fibrillation. Unlike traditional blood thinners, Apixaban offers consistent anticoagulation without the need for frequent monitoring.

Key Ingredients

• Apixaban (2.5mg) – A selective factor Xa inhibitor that prevents blood clot formation by inhibiting the clotting cascade.

Uses of APIXAZEN 2.5

APIXAZEN 2.5 is prescribed for various medical conditions, including:

1. Prevention of Stroke and Systemic Embolism – In patients with non-valvular atrial fibrillation (AF).

2. Treatment of Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE) – Helps in dissolving existing clots and preventing recurrence.

3. Post-Surgical DVT Prevention – Used in patients undergoing hip or knee replacement surgery to lower the risk of clot formation.

4. Chronic Venous Thromboembolism Management – Long-term therapy to prevent recurrent thromboembolic events.

How Does APIXAZEN 2.5 Work?

Apixaban works by selectively inhibiting factor Xa, a crucial enzyme in the blood coagulation pathway. By blocking factor Xa, the medication prevents thrombin formation, which in turn reduces fibrin clot formation. Unlike warfarin, Apixaban does not require regular blood tests for monitoring and has fewer dietary restrictions.

Dosage and Administration

The recommended dosage of APIXAZEN 2.5 depends on the condition being treated:

• For stroke prevention in atrial fibrillation: 2.5mg twice daily.

• For DVT/PE treatment: Usually initiated with higher doses, then reduced to 2.5mg twice daily for maintenance.

• Post-surgical DVT prevention: 2.5mg twice daily, starting 12-24 hours after surgery and continuing for 10-35 days.

Benefits of APIXAZEN 2.5

1. Reduces Risk of Stroke & Blood Clots – Highly effective in patients with atrial fibrillation.

2. No Routine Monitoring Required – Unlike warfarin, Apixaban does not require INR monitoring.

3. Lower Bleeding Risk – Compared to traditional anticoagulants, it has a lower incidence of major bleeding.

4. Rapid Onset of Action – Starts working within 3-4 hours after ingestion.

5. Convenient Dosage Form – Taken orally without dietary restrictions.

6. Improved Safety Profile – Lower risk of intracranial hemorrhage compared to warfarin.

Side Effects of APIXAZEN 2.5

While APIXAZEN 2.5 is generally well tolerated, some side effects may occur:

• Minor Bleeding – Nosebleeds, bruising, or prolonged bleeding from cuts.

• Gastrointestinal Issues – Nausea, diarrhea, or stomach pain.

• Fatigue or Weakness – Feeling tired or dizzy.

• Skin Reactions – Rash, itching, or allergic reactions.

• Severe Bleeding (Rare) – Internal bleeding, coughing up blood, or dark-colored stools.

Precautions and Warnings

1. Avoid in Active Bleeding Conditions – Not recommended for patients with active bleeding disorders or a history of recent surgery.

2. Caution in Kidney and Liver Disease – Adjustments may be required in renal impairment or hepatic dysfunction.

3. Pregnancy & Breastfeeding – Should be used only if absolutely necessary and prescribed by a doctor.

4. Interaction with Other Medications – Avoid NSAIDs, antiplatelets, or other anticoagulants to reduce bleeding risk.

5. Emergency Situations – In case of severe bleeding, a reversal agent such as Andexanet alfa may be required.

Drug Interactions

APIXAZEN 2.5 may interact with various medications, including:

• Antiplatelets (Aspirin, Clopidogrel) – Increases the risk of bleeding.

• NSAIDs (Ibuprofen, Naproxen) – Can lead to gastric bleeding.

• Strong CYP3A4 Inhibitors (Ketoconazole, Ritonavir) – Can increase Apixaban levels, leading to toxicity.

• Rifampin, Phenytoin – May reduce Apixaban effectiveness.

Overdose and Management

An overdose of APIXAZEN 2.5 may lead to severe bleeding complications. In case of an overdose:

1. Seek immediate medical attention.

2. Activated charcoal may help limit absorption.

3. Andexanet alfa (reversal agent) can neutralize Apixaban's effect.

APIXAZEN 2.5 Price in India

The Apixaban 2.5mg price varies based on the brand and pharmacy. On average, a strip of 10 tablets costs around ₹200-₹500 in India. Prices may differ depending on the manufacturer and location.

Frequently Asked Questions (FAQs)

1. Can APIXAZEN 2.5 be taken with food?

Yes, APIXAZEN 2.5 can be taken with or without food.

2. How long does APIXAZEN 2.5 take to work?

It starts acting within 3-4 hours of ingestion, reaching peak levels in the blood.

3. Can APIXAZEN 2.5 cause weight gain?

Weight gain is not a common side effect; however, if you notice unexplained weight gain, consult a doctor.

4. What should I do if I miss a dose?

Take the missed dose as soon as you remember. If it's close to the next dose, skip the missed dose—do not double up.

5. Is APIXAZEN 2.5 safe for long-term use?

Yes, it is generally safe for long-term use under medical supervision.

Conclusion

APIXAZEN 2.5 (Apixaban 2.5mg) is a highly effective anticoagulant for the prevention and treatment of blood clots. It offers multiple advantages, including a lower risk of bleeding, no need for routine monitoring, and convenient dosing. However, it should be used cautiously in patients with bleeding disorders, kidney disease, or concurrent medication use. Always consult a healthcare professional before starting or stopping APIXAZEN 2.5 to ensure safe and effective treatment.

Disclaimer: This article is for informational purposes only and should not replace professional medical advice. Consult your doctor before using APIXAZEN 2.5.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

BUY NOW