Apixaban, marketed as APIXAZEN 2.5, is an anticoagulant medication used to prevent and treat blood clots. This medication helps reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation. It is also used for the prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE) following knee or hip replacement surgery.

How Does It Work

• Apixaban is a direct factor Xa inhibitor.
• It works by blocking the activity of factor Xa, an enzyme crucial for blood clotting.
• By inhibiting factor Xa, apixaban decreases thrombin generation and thrombus development.

Uses of Apixaban

• Stroke prevention: Reduces the risk of stroke in patients with atrial fibrillation.
• DVT and PE prevention: Prevents blood clots in the legs (DVT) and lungs (PE) post-surgery.
• DVT and PE treatment: Treats existing blood clots and prevents their recurrence.

What is Apixaban

• Anticoagulant: A medication that helps prevent blood clots.
• Oral administration: Taken orally in tablet form.
• Nonvalvular atrial fibrillation: Used specifically for patients without heart valve issues.

Side Effects

• Bleeding
• Nausea
• Severe bleeding
• Allergic reactions (rash, itching, swelling)

Safety Information

• Before taking Apixaban:
  • Inform your doctor of any allergies.
  • Discuss any medical history of bleeding disorders or liver disease.
• Precautions:
  • Avoid activities that may increase your risk of bleeding or injury.
  • Inform your healthcare provider about all the medications you are taking to avoid interactions.
• Emergency:
  • Seek immediate medical attention if you experience symptoms of severe bleeding or an allergic reaction.

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