Vildagliptin 50 mg
Jul 05, 2022
VILDIABATE 50, manufactured by Steris Healthcare, contains Vildagliptin 50 mg, a DPP-4 inhibitor used to manage blood sugar levels in patients with Type 2 diabetes mellitus. It works by increasing insulin release and reducing glucose production, often prescribed alone or in combination with Metformin. It is a prescription-only medicine, priced at ₹173 per strip from Steris Healthcare.
What Is VILDIABATE 50?
VILDIABATE 50 is a tablet form of anti-diabetic medicine produced by Steris Healthcare Ltd. It is a member of the class of medications known as DPP-4 inhibitors (gliptins). These drugs are used for the regulation of blood sugar levels with minimum risks of weight gain and hypoglycemia in comparison with previous generations of anti-diabetic medications.
Vildagliptin exerts its effect by inhibiting the enzyme, dipeptidyl peptidase-4 (DPP-4) that usually degrades incretin hormones such as GLP-1 and GIP. By preventing DPP-4 from action, this drug increases the activity time of these hormones, resulting in the stimulation of insulin secretion in case of elevated blood sugar level and the inhibition of glucose production by the liver.
The tablet is packaged in blisters.
What Is the Drug Vildagliptin 50 mg Used For?
50 mg vildagliptin is indicated for the treatment of hyperglycemia in adults suffering from Type 2 diabetes mellitus. It is usually recommended along with other treatments for diabetes like exercise and dietary plans.
Vildagliptin 50 mg Uses / Vildagliptin 50 mg Tablet Uses
- Type 2 diabetes management — as monotherapy when diet and exercise alone aren't sufficient
- Combination therapy with Metformin — when Metformin alone doesn't achieve target blood sugar control
- Combination with sulfonylureas — in patients who need additional glycemic control
- Combination with insulin — in select cases, under close medical supervision
- Triple therapy — sometimes combined with Metformin and a sulfonylurea for patients with more advanced insulin resistance
What Conditions Does Vildagliptin 50 mg Treat?
VILDIABATE 50 specifically treats Type 2 diabetes mellitus — it is not approved for Type 1 diabetes or diabetic ketoacidosis, both of which require insulin-based treatment.
Is Vildagliptin 50 mg Used With Metformin?
Yes. Vildagliptin is very commonly prescribed alongside Metformin, either as two separate tablets or as a fixed-dose combination. This pairing is one of the most widely used second-line diabetes treatment approaches globally, as the two drugs work through different mechanisms — Metformin reduces liver glucose production and improves insulin sensitivity, while Vildagliptin boosts incretin hormone activity.
Vildagliptin 50 mg Benefits
- Effective blood sugar control, especially post-meal (postprandial) glucose spikes
- Low risk of hypoglycemia when used alone (not combined with insulin or sulfonylureas)
- Weight-neutral — does not typically cause weight gain, unlike some other diabetes drugs
- Convenient dosing — usually twice daily
- Well-tolerated in most adult and elderly patients
- Can be combined with several other diabetes medications for flexible treatment plans
Vildagliptin 50 mg Dosage
Note: Dosage must always be determined by your treating physician based on your blood sugar levels, kidney function, and other medications. The following is general reference information only.
Vildagliptin 50 mg Dosage for Diabetes
- Standard dose: 50 mg once or twice daily, depending on the treatment combination
- As monotherapy or with Metformin: Usually 50 mg twice daily (100 mg total per day)
- Combined with a sulfonylurea: Often reduced to 50 mg once daily in the morning, since sulfonylureas already carry hypoglycemia risk
- Maximum recommended dose: 100 mg per day (50 mg twice daily)
What Is the Best Time of Day to Take Vildagliptin 50 mg?
VILDIABATE 50 can be taken in the morning and evening (roughly 12 hours apart) if prescribed twice daily, or in the morning if prescribed once daily. It can be taken with or without food, though taking it at the same times each day helps maintain steady blood sugar control.
Vildagliptin 50 mg Tablet Uses in Adults
VILDIABATE 50 is approved for use in adults (18 years and older) with Type 2 diabetes. It is not recommended for use in children, as safety and efficacy have not been established in the pediatric population.
Can I Take Vildagliptin 50 mg Daily?
Yes, VILDIABATE 50 is designed for daily, ongoing use as part of long-term diabetes management. Consistency is important — skipping doses can lead to poor blood sugar control.
Can I Take Vildagliptin 50 mg on an Empty Stomach?
Yes, it can technically be taken with or without food. However, some patients find taking it with meals reduces mild stomach discomfort. Follow your doctor's specific instructions.
Vildagliptin 50 mg Side Effects
Like all medications, VILDIABATE 50 can cause side effects, though not everyone experiences them.
Common side effects:
- Headache
- Dizziness
- Nausea
- Mild tremor
- Upper respiratory tract symptoms (in some patients)
- Joint pain (arthralgia)
- Constipation
Less common side effects:
- Mild swelling of hands/feet (peripheral edema), especially when combined with certain other medications
- Fatigue
- Skin reactions (rash, itching)
Rare but serious side effects (seek medical attention immediately):
- Signs of liver problems — yellowing of skin/eyes, dark urine, unusual tiredness, loss of appetite
- Severe abdominal pain (possible sign of pancreatitis)
- Signs of allergic reaction — swelling of face/lips/throat, difficulty breathing, severe rash
- Blistering skin conditions (very rare)
If any severe or persistent symptoms occur, stop the medication and consult your doctor immediately rather than self-adjusting the dose.
Does Vildagliptin Cause Liver Problems?
Liver problems with vildagliptin are rare but have been reported in a small number of cases. Regular liver function monitoring is generally recommended, especially during the first year of treatment, and the medication should be discontinued if signs of liver dysfunction (jaundice, dark urine, persistent nausea) appear.
Can Vildagliptin 50 mg Affect the Liver?
Yes, in rare instances. Because of this, doctors typically recommend baseline and periodic liver function tests, particularly for patients with pre-existing liver conditions. VILDIABATE 50 is generally not recommended for patients with moderate to severe liver impairment.
Can Vildagliptin 50 mg Affect Kidneys?
Vildagliptin is partly cleared through the kidneys, so patients with reduced kidney function may need a dose adjustment. Your doctor will typically check kidney function (via creatinine/eGFR tests) before and during treatment, especially in elderly patients or those with existing kidney disease.
Does Vildagliptin 50 mg Cause Hypoglycemia?
When taken alone or with Metformin, vildagliptin carries a low risk of hypoglycemia (low blood sugar). However, the risk increases when combined with sulfonylureas or insulin, which is why dose adjustments are often made in these combination therapies.
How Does Vildagliptin 50 mg Affect the Heart?
Vildagliptin is generally considered to have a neutral cardiovascular safety profile based on available clinical data — it does not significantly increase or decrease cardiovascular risk in most patients. That said, patients with a history of heart failure should discuss their cardiac history with their doctor, as DPP-4 inhibitors as a class have been studied for potential associations with heart failure hospitalization in specific patient subgroups. Regular monitoring is advised for those with pre-existing heart conditions.
Is Vildagliptin 50 mg Safe for Elderly Patients?
xYes, vildagliptin is generally considered safe for elderly patients and does not typically require dose adjustment based on age alone. However, elderly patients often have reduced kidney function, so doctors may monitor kidney parameters more closely in this age group.
Drug Interactions With VILDIABATE 50
Always inform your doctor about all medications, supplements, and herbal products you are currently taking.
Medications that may interact with VILDIABATE 50:
- Sulfonylureas (e.g., glimepiride, gliclazide) — increases hypoglycemia risk; dose adjustment often needed
- Insulin — combination increases hypoglycemia risk; requires careful monitoring
- ACE inhibitors (e.g., enalapril, ramipril) — may slightly increase risk of angioedema (swelling) when combined with DPP-4 inhibitors
- Diuretics — can affect blood sugar control and kidney function monitoring
- Corticosteroids — may raise blood sugar levels, counteracting vildagliptin's effect
- Other diabetes medications — combination therapy is common but must be dose-adjusted by your doctor to avoid hypoglycemia
What Are the Precautions Before Taking Vildagliptin 50 mg?
- Inform your doctor about any history of liver disease, kidney disease, pancreatitis, or heart failure
- Regular blood sugar monitoring (HbA1c) every 3 months is recommended
- Liver function tests before starting and periodically during treatment
- Not recommended during pregnancy or breastfeeding unless specifically advised by a doctor
- Should not be used in Type 1 diabetes or diabetic ketoacidosis
Lifestyle Questions: Diet, Alcohol, and Exercise
What Foods Should I Avoid While Taking Vildagliptin 50 mg?
There are no specific foods that must be strictly avoided, but patients with diabetes are generally advised to limit refined sugars, sugary beverages, and high-glycemic-index foods to support the medication's effectiveness. A balanced, diabetic-friendly diet works best alongside VILDIABATE 50.
Can I Drink Alcohol With Vildagliptin 50 mg?
Quick Answer: Alcohol should be consumed cautiously or avoided, as it can affect blood sugar levels unpredictably (causing both high and low blood sugar episodes) and may increase strain on the liver, which is already something to monitor with this medication. Discuss your alcohol habits with your doctor.
Can I Exercise While Taking Vildagliptin 50 mg?
Yes, regular physical activity is encouraged and complements the medication's blood-sugar-lowering effect. Since the hypoglycemia risk is low with vildagliptin alone, most patients can exercise normally, though it's wise to monitor blood sugar levels, especially when starting a new exercise routine.
Does Vildagliptin 50 mg Help With Weight Loss?
Quick Answer: Vildagliptin is considered weight-neutral — it does not typically cause significant weight loss or weight gain, unlike some other diabetes medications. Patients seeking weight loss alongside diabetes control should discuss additional lifestyle strategies or alternative medications with their doctor.
Can Diabetics Take Vildagliptin 50 mg Every Day?
Yes, VILDIABATE 50 is intended for daily, long-term use as part of ongoing Type 2 diabetes management, alongside regular monitoring by a healthcare provider.
Tab Vildagliptin 50 mg Price
VILDIABATE 50 is manufactured and priced affordably by Steris Healthcare to support consistent, long-term diabetes management.
- Vildagliptin 50 mg price: ₹173 per strip
- Available through licensed pharmacies and hospital dispensaries with a valid prescription
Patients searching for vildagliptin 50 mg price or comparing vildagliptin 50 mg price in India across brands should note that pricing can vary by manufacturer, strip size, and regional taxation. Steris Healthcare positions VILDIABATE 50 as a quality-assured, cost-effective option for patients requiring ongoing diabetes therapy.
For those looking to buy Vildagliptin 50 mg online, always ensure the pharmacy is licensed and requests a valid prescription before dispensing — this protects against counterfeit medication and ensures product authenticity.
If your prescription specifies tab vildagliptin 50 or tab vildagliptin 50 mg, VILDIABATE 50 by Steris Healthcare meets the required composition and dosage standards, manufactured under quality-controlled pharmaceutical practices.
Vildagliptin Tablets 50mg Price for Bulk & Institutional Buyers
Steris Healthcare also caters to institutional and bulk requirements:
- Vildagliptin 50 mg manufacturer: Steris Healthcare
- Vildagliptin 50 mg supplier / distributor / wholesale inquiries: Available for pharmacies, hospitals, and healthcare distributors seeking affordable Vildagliptin 50 mg tablets in bulk quantities
- Businesses looking for the best Vildagliptin 50 mg tablets at competitive rates can reach out to Steris Healthcare directly for wholesale and distributor pricing
Additional Information You Should Know
A few important points often overlooked but essential for safe, effective use:
Pregnancy and breastfeeding: VILDIABATE 50 is generally not recommended during pregnancy or breastfeeding due to limited safety data. Insulin is typically preferred for blood sugar control during pregnancy. Discuss alternative options with your doctor if you are planning a pregnancy.
Missed dose: If a dose is missed, take it as soon as remembered unless it's close to the next scheduled dose — do not double up.
Storage instructions: Store VILDIABATE 50 at room temperature, away from moisture and direct sunlight, and keep out of reach of children.
Overdose: In case of accidental overdose, seek immediate medical attention, particularly to monitor for hypoglycemia symptoms such as sweating, shakiness, confusion, or rapid heartbeat.
Pancreatitis awareness: Though rare, DPP-4 inhibitors like vildagliptin have been associated with isolated cases of pancreatitis. Patients should be aware of symptoms like severe, persistent abdominal pain (sometimes radiating to the back), and seek immediate medical attention if these occur — the medication should be discontinued if pancreatitis is suspected.
Skin reactions: Rare cases of blistering skin conditions have been reported with DPP-4 inhibitors as a class. Any unusual skin blistering or peeling should be reported to a doctor promptly.
Regular monitoring matters: Long-term success with VILDIABATE 50 depends heavily on regular HbA1c testing, periodic liver and kidney function checks, and open communication with your healthcare provider about any new symptoms or medications.
Frequently Asked Questions
Q: Can VILDIABATE 50 be taken with insulin?
Yes, in select cases under close medical supervision, though the combination increases hypoglycemia risk and requires careful dose management.
Q: Is VILDIABATE 50 safe for patients with kidney disease?
It can be used but often requires dose adjustment based on kidney function; always inform your doctor of any kidney-related history.
Q: How soon does VILDIABATE 50 start working?
Blood sugar improvements are often seen within the first few weeks, though full benefits are typically assessed through HbA1c testing after 3 months.
Q: Can VILDIABATE 50 be stopped suddenly?
It should not be stopped abruptly without medical guidance, as blood sugar levels can rise quickly, especially if not replaced with an alternative treatment plan.
Q: Is VILDIABATE 50 the same as insulin?
No, it is an oral tablet that works differently from insulin — it enhances the body's own insulin response rather than replacing insulin directly.
About Steris Healthcare
Steris Healthcare is committed to manufacturing quality-assured, affordable pharmaceutical products under strict regulatory compliance. VILDIABATE 50 (Vildagliptin 50 mg) is formulated to meet pharmacopoeial standards, ensuring consistent potency and safety for long-term diabetes management. This content has been compiled using standard clinical references on DPP-4 inhibitor therapy and is intended for general informational purposes.
Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice. VILDIABATE 50 is a prescription medication — always consult a qualified physician before starting, stopping, or changing your dosage. Individual results and side effects may vary. In case of a medical emergency, contact a healthcare provider immediately.
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