Sacubitril and Valsartan Tablets – Uses, Benefits & Side Effects
Sep 20, 2025
Sacubitril 49 mg/valsartan 51 mg is a powerful combination medicine marketed under the brand name SACUBRIGHT 100, designed to manage heart failure effectively. This medication combines the benefits of sacubitril and valsartan to improve heart function, reduce symptoms, and enhance quality of life for patients with chronic heart failure.
What are Sacubitril and Valsartan Tablets?
Sacubitril 49 mg and Valsartan 51 mg work together as a combination therapy:
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Sacubitril enhances natural peptides in the body, which relax blood vessels, reduce sodium levels, and ease fluid buildup.
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Valsartan, an angiotensin receptor blocker (ARB), lowers blood pressure and prevents further strain on the heart.
Together, they form a powerful medicine known as an ARNI (Angiotensin Receptor Neprilysin Inhibitor), a modern standard in treating heart failure.
Sacubitril and Valsartan Tablets Uses
The main uses of sacubitril and valsartan tablets include:
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Treatment of chronic heart failure with reduced ejection fraction (HFrEF).
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Reducing the risk of hospitalization due to worsening heart failure.
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Improving exercise tolerance and daily activity levels.
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Enhancing quality of life and lowering the chances of cardiovascular death.
Patients on sacubitril 49 mg / valsartan 51 mg often experience better symptom control, less fatigue, and improved ability to perform daily tasks.
How SACUBRIGHT 100 Works
SACUBRIGHT 100 combines sacubitril and valsartan in a balanced ratio:
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Sacubitril 49 mg helps break down harmful enzymes while boosting protective peptides that relax blood vessels.
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Valsartan 51 mg blocks angiotensin-II, a substance that narrows blood vessels and raises blood pressure.
This dual action allows the heart to pump more efficiently while reducing pressure and strain.
Benefits of Sacubitril 49 mg / Valsartan 51 mg
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Provides better outcomes than traditional heart failure medicines.
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Reduces fluid buildup, shortness of breath, and swelling.
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Lowers the chance of emergency hospital admissions.
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Improves energy, stamina, and heart performance.
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Offers long-term protection to the heart.
Side Effects of Sacubitril and Valsartan Tablets
While generally safe, some patients may experience side effects, such as:
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Dizziness or lightheadedness
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Low blood pressure (hypotension)
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Increased potassium levels
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Cough
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Kidney function changes
Rare but serious: angioedema (swelling of face, lips, tongue, or throat). Immediate medical help is needed if this occurs.
Precautions for Patients
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Avoid if pregnant or breastfeeding.
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Do not take together with ACE inhibitors.
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Regular monitoring of blood pressure, kidney function, and potassium levels is necessary.
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Inform your doctor if you have severe kidney or liver disease.
Why Choose Steris Healthcare for SACUBRIGHT 100?
At Steris Healthcare, we are committed to providing affordable, high-quality, and safe medicines. Our product SACUBRIGHT 100 (Sacubitril 49 mg / Valsartan 51 mg tablets) is manufactured under WHO-GMP certified facilities, ensuring trust and reliability.
Patients and healthcare professionals across India trust Steris because we prioritize:
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Strict quality standards.
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Wide availability across India.
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Affordable pricing for long-term treatment.
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Patient-focused care with transparency and trust.
Frequently Asked Questions
Q1: What is the use of sacubitril and valsartan tablets?
They are used to treat chronic heart failure with reduced ejection fraction, reduce hospitalization risk, and improve quality of life.
Q2: How long does it take for SACUBRIGHT 100 to work?
Some patients notice improvements within weeks, while long-term benefits are achieved with regular use.
Q3: Can I take sacubitril and valsartan with other heart medicines?
Yes, but avoid combining with ACE inhibitors. Always follow your doctor’s guidance.
Q4: Is it safe for elderly patients?
Yes, but dosage adjustments and regular monitoring may be required.
Q5: Can sacubitril 49 mg/valsartan 51 mg cure heart failure?
It does not cure heart failure but controls symptoms, improves survival, and enhances quality of life.
Conclusion
Sacubitril 49 mg / Valsartan 51 mg tablets is a modern, effective solution for patients struggling with heart failure. By lowering strain on the heart, reducing hospital visits, and improving daily life, this treatment has become a preferred choice for both patients and doctors.
If you or your loved ones are managing heart failure, consult your doctor today about starting SACUBRIGHT 100 from Steris Healthcare – a trusted name in advanced cardiovascular care.
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