RABISTRUM LS  Levosulpride (75mg SR), Rabeprazole (20mg) : uses , side effects , pictures , and more information....

Jul 23, 2024

RABISTRUM LS 

Levosulpride (75mg SR), Rabeprazole (20mg)

RABISTRUM LS combines two potent pharmaceutical ingredients: Levosulpride (75mg SR) and Rabeprazole (20mg). This combination medication is primarily used to manage and treat gastrointestinal disorders such as gastroesophageal reflux disease (GERD) and functional dyspepsia. Each component plays a significant role in alleviating symptoms and improving the quality of life for patients.

What is Levosulpride?

Levosulpride is an atypical antipsychotic and prokinetic agent that works by enhancing the motility of the gastrointestinal tract. It is particularly effective in treating conditions like GERD and functional dyspepsia, where delayed gastric emptying and motility issues are common.

Mechanism of Action

Levosulpride functions by blocking the dopamine D2 receptors in the gut, leading to an increase in gastrointestinal motility. This helps in faster gastric emptying and reduces symptoms such as bloating, nausea, and stomach discomfort.

What is Rabeprazole?

 It is widely used to treat conditions caused by excessive stomach acid such as GERD, peptic ulcers, and Zollinger-Ellison syndrome.

Mechanism of Action

Rabeprazole inhibits the hydrogen-potassium ATPase enzyme system (the proton pump) in the stomach lining. 

Uses of RABISTRUM LS

Gastroesophageal Reflux Disease (GERD)

GERD is a chronic condition where stomach acid frequently flows back into the esophagus, causing irritation and symptoms like heartburn, chest pain, and regurgitation. RABISTRUM LS helps manage GERD by:

  • Enhancing gastrointestinal motility with Levosulpride.
  • Reducing stomach acid production with Rabeprazole.

Functional Dyspepsia

Functional dyspepsia is characterized by persistent or recurring indigestion with no clear cause. Symptoms include bloating, nausea, and upper abdominal pain. RABISTRUM LS provides relief by:

  • Improving gastric motility and emptying with Levosulpride.
  • Decreasing stomach acid production with Rabeprazole.

Dosage and Administration

RABISTRUM LS is usually taken once daily before meals, preferably in the morning. The sustained-release formulation of Levosulpride ensures a prolonged effect, while Rabeprazole provides acid suppression throughout the day.

General Dosage Guidelines

  • Adults: One tablet of RABISTRUM LS per day.
  • Elderly and Patients with Renal Impairment: Dosage adjustments may be necessary.

It is crucial to follow the prescribing doctor's instructions and not to alter the dosage without medical advice.

Side Effects of RABISTRUM LS

Common Side Effects

  • Levosulpride: Drowsiness, fatigue, dizziness, and sometimes restlessness.
  • Rabeprazole: Headache, diarrhea, nausea, and abdominal pain.

Rare but Serious Side Effects

  • Levosulpride: Extrapyramidal symptoms (tremors, rigidity), hormonal imbalances like increased prolactin levels.
  • Rabeprazole: Severe allergic reactions, liver dysfunction, and Clostridium difficile infection.

Interactions with Other Medications

RABISTRUM LS can interact with other medications, which may either enhance or reduce its effectiveness or increase the risk of side effects.

Rabeprazole Interactions

  • Warfarin: May increase the risk of bleeding.
  • Methotrexate: Rabeprazole can increase methotrexate levels and toxicity.
  • Antifungal Agents: Rabeprazole may reduce the effectiveness of antifungal drugs like ketoconazole.

Precautions and Warnings

Pregnancy and Breastfeeding

  • Levosulpride: Should be used with caution during pregnancy and breastfeeding due to limited data on safety.
  • Rabeprazole: Generally considered safe, but should only be used if clearly needed and prescribed by a doctor.

Renal and Hepatic Impairment

Patients with severe renal or hepatic impairment should use RABISTRUM LS with caution and under close medical supervision.

Price of RABISTRUM LS

The price of RABISTRUM LS can vary based on the manufacturer, location, and pharmacy. On average, a strip of 10 tablets may cost between INR 150 to INR 300. Patients are advised to check with local pharmacies or online retailers for the most accurate pricing.

Conclusion

RABISTRUM LS, combining Levosulpride (75mg SR) and Rabeprazole (20mg), is an effective medication for managing gastrointestinal disorders like GERD and functional dyspepsia. By addressing both motility and acid-related issues, it offers comprehensive relief from symptoms, improving the patient's quality of life. However, it is essential to use this medication under medical supervision, considering potential side effects and interactions. Always follow the prescribed dosage and consult your healthcare provider for any concerns regarding its use. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

For further information 

Email: info@sterispharma.com /  contact@sterispharma.com

Call/WhatsApp:  7877551268, 7849827488 

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