"GLIMITERIS M1 & M2: Advanced Diabetes Control"

Mar 13, 2024

GLIMITERIS M1

Glimepiride & Metformin Hydrochloride Prolonged Release

"GLIMITERIS M1 & M2 Glimepiride & Metformin Hydrochloride Prolonged Release"

Glimepiride and Metformin Hydrochloride Prolonged Release (referred to as GLIMITERIS M1 in medical formulations) combines two antihyperglycemic agents with complementary mechanisms to improve glycemic control in adults with type 2 diabetes mellitus. This combination is particularly beneficial for patients who do not achieve adequate blood sugar control with metformin or glimepiride alone.

Overview of Components

  • Glimepiride: A sulfonylurea that increases insulin secretion from the pancreas, thereby lowering blood glucose levels.
  • Metformin Hydrochloride: Belongs to the biguanide class, it decreases hepatic glucose production and intestinal absorption of glucose, and improves insulin sensitivity.

Mechanism of Action

  • Dual Action: The combination targets different pathways in the management of type 2 diabetes, providing a more comprehensive approach to controlling blood glucose levels.
  • Prolonged Release Formula: Designed to release the medication slowly over time, improving glycemic control throughout the day with a lower risk of side effects.

Indications

  • Type 2 Diabetes Management: For patients who require additional glycemic control beyond monotherapy with metformin or sulfonylurea.
  • Step-up Therapy: Recommended for patients whose diabetes is not adequately controlled with diet and exercise alone.

Benefits

  • Enhanced Control: Significantly improves HbA1c levels, offering better control over blood sugar levels.
  • Convenience: The prolonged-release formula allows for once or twice daily dosing, enhancing patient compliance.
  • Reduced Hypoglycemia Risk: Compared to other sulfonylureas, glimepiride has a lower risk of causing hypoglycemia.

Side Effects and Considerations

  • Common Side Effects: Include hypoglycemia, gastrointestinal disturbances, and potential weight gain.
  • Monitoring: Regular monitoring of blood glucose and HbA1c levels is essential to adjust doses and prevent complications.
  • Contraindications: Not suitable for patients with type 1 diabetes, diabetic ketoacidosis, or severe renal impairment.

Patient Education and Management

  • Lifestyle Modifications: Importance of diet, exercise, and regular blood glucose monitoring as part of the overall treatment plan.
  • Adherence: Encouraging adherence to medication schedules to ensure optimal glycemic control.
  • Awareness: Educating patients on recognizing signs of hypoglycemia and how to manage it.

In conclusion, Glimepiride & Metformin Hydrochloride Prolonged Release (GLIMITERIS M1) is an effective combination therapy for managing type 2 diabetes. It offers the benefits of improved glycemic control, convenience, and a reduced risk of hypoglycemia. However, it requires careful patient selection, monitoring, and education to maximize its benefits and minimize risks.  A group of highly skilled pharmaceutical professionals founded a specialist pharmaceutical in February 2018 such as Steris Healthcare Pvt Ltd.Sterispharma is a WHO, GMP, and ISO-certified pharma company based in Navi Mumbai. They provide quality medicines at the best price to customers in India as per the standard parameters of WHO. With a steris online pharmacy, you can buy and get home delivery of medicines at your doorsteps. Our main goal at Steris is to provide a wide range of healthcare goods to meet the various needs of the healthcare sector. Steris is dedicated to satisfying the needs of the healthcare industry, whether it be with regard to specialty treatments, rare disease meds, or necessary pharmaceuticals. Steris healthcare products range covers almost every cadre of requirement in today's Medical scenario, widely prescribed under categories like Cardiology, Asthama, Respiratory, Nasal, Diabetic, Endocrinology, Cadiology, Gastrology, Orthopaedic, Anti-infective/antibiotic, General, Urology, Neurology, Nephrology, Oncology, Gynaecology, Pediatric, Dental & Derma range of Products.

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