Prazosin SR 5.0 Tablet – Uses, Benefits, Dosage, Side Effects & Price

PRAZOPRIME XL 5 is a sustained-release tablet formulation containing Prazosin Hydrochloride 5 mg, a well-known antihypertensive agent widely used for the management of high blood pressure (hypertension), benign prostatic hyperplasia (BPH), and heart failure. 

Prazosin belongs to a class of medications called alpha-1 adrenergic blockers, which help relax blood vessels and smooth muscles in various parts of the body, improving blood flow and lowering blood pressure. The sustained-release (SR) version, PRAZOPRIME XL 5, enhances patient compliance and maintains steady plasma concentration over an extended period.

How Prazosin SR 5.0 (PRAZOPRIME XL 5) Works

The mechanism of action of Prazosin SR 5.0 is based on its ability to block alpha-1 adrenergic receptors located in the vascular smooth muscles. By inhibiting these receptors, prazosin causes vasodilation—a process in which the blood vessels relax and widen—leading to a decrease in peripheral vascular resistance and, consequently, a reduction in blood pressure.

Additionally, in patients with benign prostatic hyperplasia (BPH), Prazosin helps relax the smooth muscle of the bladder neck and prostate gland, making it easier to urinate and relieving symptoms such as weak stream, hesitancy, and nocturia.

The sustained-release (SR) feature of PRAZOPRIME XL 5 ensures that the drug is released gradually, maintaining its therapeutic effect over 24 hours with a single daily dose. This reduces fluctuations in blood concentration levels and minimizes potential side effects like sudden drops in blood pressure.

What are the Benefits of Prazosin SR 5.0

• Effective Blood Pressure Control: Prazosin SR 5.0 is highly effective in reducing both systolic and diastolic blood pressure by relaxing arterial walls.

• Improves Heart Function: It reduces cardiac workload by decreasing peripheral resistance, which can be beneficial in managing congestive heart failure.

• Relief in BPH Symptoms: It helps improve urinary flow and reduce symptoms associated with benign prostatic hyperplasia.

• Prevents Hypertensive Crisis: Useful in cases of severe hypertension where controlled lowering of blood pressure is required.

• Enhanced Tolerability: The sustained-release form provides a smoother therapeutic effect, minimizing “first-dose hypotension.”

Key Benefits of PRAZOPRIME XL 5 (Prazosin SR 5.0)

• Provides 24-hour control of hypertension with a single daily dose.

• Reduces the risk of orthostatic hypotension due to gradual release of medication.

• Improves quality of life in patients with both hypertension and urinary difficulties.

• Safe and effective for long-term management of essential hypertension.

• Manufactured by Steris Healthcare Pvt. Ltd., ensuring high-quality standards, WHO-GMP certification, and consistent bioavailability.

Side Effects of Prazosin SR 5.0

Like all medications, PRAZOPRIME XL 5 (Prazosin SR 5.0) may cause side effects in some individuals. These effects are usually mild and temporary, especially as the body adjusts to the medication.

Common Side Effects of Prazosin SR 5.0

• Dizziness or lightheadedness (especially after the first dose)

• Fatigue or weakness

• Headache

• Nausea or mild stomach discomfort

• Nasal congestion

• Palpitations or rapid heartbeat

• Drowsiness

Serious Side Effects of Prazosin SR 5.0

• Severe hypotension (very low blood pressure)

• Fainting or loss of consciousness

• Irregular heartbeat or chest pain

• Swelling in feet, ankles, or hands

• Difficulty breathing or shortness of breath

• Prolonged erection (a rare side effect called priapism)

Available Substitute for Prazosin SR 5.0

Some alternative brands containing Prazosin 5 mg include:

• Minipress XL 5 mg Tablet

• Prazopress XL 5 mg Tablet

• Prazopress SR 5 mg Tablet

Dosage Guidelines for Prazosin SR 5.0

The dosage of PRAZOPRIME XL 5 (Prazosin SR 5.0) should be individualized based on the patient’s condition and response to treatment.

Typical Adult Dosage:

• Hypertension: Start with 1 mg at bedtime for the first few days, gradually increasing to 5 mg daily (PRAZOPRIME XL 5).

• Benign Prostatic Hyperplasia (BPH): Usually, 2–5 mg once daily is effective.

• Heart Failure: May require dose titration under medical supervision.

Administration Tips:

• Take the tablet once daily, preferably at the same time each day.

• Swallow whole with water; do not crush or chew.

• Take the first dose at bedtime to minimize dizziness.

• Continue medication even if you feel well—do not stop abruptly without consulting your doctor.

Precautions & Warnings: Prazosin SR 5.0

Before starting PRAZOPRIME XL 5, patients should consider the following precautions:

1. First Dose Effect: The initial dose may cause a sudden drop in blood pressure, resulting in dizziness or fainting. Take the first dose at night while lying down.

2. Driving & Operating Machinery: Avoid driving or using heavy machinery after taking the first few doses.

3. Alcohol Consumption: Avoid alcohol, as it may potentiate dizziness or fainting.

4. Heart Conditions: Inform your doctor if you have a history of heart disease or arrhythmia.

5. Kidney or Liver Impairment: Dose adjustment may be necessary.

6. Pregnancy & Lactation: Use only under medical supervision.

7. Drug Interactions: Prazosin may interact with beta-blockers, phosphodiesterase inhibitors (like sildenafil), or other antihypertensive drugs.

Frequently Asked Questions

1. What is Prazosin 5 mg used for?
Prazosin 5 mg is used to treat high blood pressure (hypertension) and symptoms of benign prostatic hyperplasia (BPH). It helps relax blood vessels and improve urine flow.

2. How does Prazosin work?
It blocks alpha-1 adrenergic receptors, relaxing blood vessels and easing blood flow, thus reducing blood pressure.

3. Can Prazosin SR 5.0 be used at night?
Yes, it’s recommended to take the first dose at bedtime to prevent dizziness from low blood pressure.

4. Is Prazosin a beta-blocker?
No, Prazosin is an alpha-1 blocker, not a beta-blocker.

5. What is the maximum dose of Prazosin?
The maximum daily dose can go up to 20 mg/day (divided doses), depending on the condition and patient tolerance.

6. Can I stop Prazosin suddenly?
No, sudden discontinuation may cause rebound hypertension. Always consult your doctor before stopping.

7. Can Prazosin be taken with other antihypertensive drugs?
Yes, but it should be under strict medical supervision to prevent an excessive drop in blood pressure.

Conclusion

PRAZOPRIME XL 5 (Prazosin SR 5.0) by Steris Healthcare Pvt. Ltd. is a trusted and advanced formulation designed to manage hypertension, improve heart health, and ease urinary symptoms associated with BPH. With its sustained-release technology, it provides long-lasting blood pressure control and improved patient comfort. Always take the medication as prescribed and follow the dosage guidelines for optimal therapeutic results.

About Steris Healthcare Pvt. Ltd.

Steris Healthcare Pvt. Ltd. is a leading pharmaceutical company known for its commitment to delivering high-quality, affordable, and safe medicines across India. With WHO-GMP certified manufacturing units, Steris Healthcare ensures excellence in formulation, safety, and patient outcomes.

For further information:

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042, 8824175417

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