Praziquantel 600 mg Tablet for Parasitic Infections

Introduction

PRAZIQUNA PLUS is a high-quality anthelmintic medication containing praziquantel 600 mg, designed for the effective treatment of parasitic worm infections. Manufactured and marketed by Steris Healthcare Pvt. Ltd, this pharmaceutical product ensures high purity, optimal efficacy, and patient safety for conditions caused by schistosomes, tapeworms, and other fluke infections.

Composition of PRAZIQUNA PLUS

• Active Ingredient: Praziquantel 600 mg

• Form: Oral Tablet

• Brand Name: PRAZIQUNA PLUS

• Packaging: Blister pack or strip (as per requirement)

What is Praziquantel 600 mg?

Praziquantel 600 mg is an antiparasitic medication used to treat infections caused by flatworms such as schistosomes (blood flukes) and tapeworms. It is listed on the World Health Organization’s (WHO) list of essential medicines, signifying its importance in public health.

Mechanism of Action

Praziquantel works by:

• Increasing the permeability of the parasite's cell membrane to calcium ions.

• This causes muscle contractions and paralysis in the parasite.

• The worms are then dislodged from the tissues and eliminated through the host's immune system and intestinal tract.

This makes tab praziquantel 600 mg highly effective against a wide range of parasitic infections.

Uses and Indications of Praziquantel 600 mg Tablet

Tab Praziquantel is indicated for the treatment of the following conditions:

• Schistosomiasis (caused by Schistosoma species)

• Liver fluke infections (Clonorchis sinensis, Opisthorchis viverrini)

• Intestinal tapeworms (Taenia saginata, Taenia solium, Diphyllobothrium latum)

• Cysticercosis (in specific regimens, often with corticosteroids)

• Hydatid disease (used in combination therapy)

• Other trematode infections

Dosage and Administration

Praziquantel 600 mg dosage is determined based on the infection type, patient’s body weight, and age.
Typical dosage recommendations:

• Schistosomiasis: 20 mg/kg body weight, 3 times a day

• Tapeworm infections: 5–10 mg/kg as a single dose

• Liver fluke infections: 25 mg/kg, 3 times a day

Always administer with food to enhance absorption. Tablets should be swallowed with water and not chewed.

Efficacy and Clinical Evidence

• Clinical studies show over 90% cure rates in most cases of schistosomiasis and tapeworm infections.

• WHO and CDC recommend praziquantel tablets as first-line therapy in endemic areas.

• Rapid action and high tolerability make praziquantel 600 mg tablet a trusted choice worldwide.

Side Effects and Safety Profile

While generally well tolerated, praziquantel tablet side effects may include:

• Nausea, abdominal discomfort

• Dizziness or headache

• Fatigue

• Rash or itching

• Mild fever

These are usually transient and resolve without intervention. In some cases, symptoms may result from worm die-off reactions rather than the drug itself.

Contraindications and Precautions

Avoid PRAZIQUNA PLUS in:

• Hypersensitivity to praziquantel

• Ocular cysticercosis (risk of damage from dying larvae)

• Children under 4 years

• Pregnant women (unless benefits outweigh risks)

• Severe liver impairment (drug is hepatically metabolized)

Caution: Avoid driving or operating machinery after taking the dose due to possible dizziness.

Drug Interactions

• CYP450 inducers like rifampin may reduce praziquantel levels.

• Antiepileptic drugs like phenytoin, carbamazepine can interfere with its effectiveness.

• Cimetidine may increase blood levels of praziquantel.

Regulatory Status

• Praziquantel 600 mg is WHO-GMP certified.

• Approved by Indian drug regulatory authorities for human use.

• Listed as an essential medicine by WHO.

Frequently Asked Questions (FAQs)

Q1. What is praziquantel 600 mg used for?

Praziquantel 600 mg is used to treat parasitic worm infections such as schistosomiasis, tapeworm infections, and liver fluke infestations.

Q2. How should I take tab praziquantel 600 mg?

Always take it with food. Swallow the tablet whole with water. Do not chew or crush unless advised by your physician.

Q3. What are the side effects of praziquantel tablet?

Common side effects include nausea, dizziness, headache, and mild abdominal pain. These are usually temporary.

Q4. Can I take praziquantel with other medications?

Inform your doctor about all medications you're taking. Drugs like rifampin and phenytoin may interact with praziquantel.

Q5. Is PRAZIQUNA PLUS safe during pregnancy?

It should be avoided unless prescribed by a doctor after assessing the benefits and risks.

Q6. Why choose Steris Healthcare’s praziquantel tablet?

Steris Healthcare offers WHO-GMP certified products, high bioavailability, superior efficacy, and reliable support across India.

Conclusion

PRAZIQUNA PLUS containing praziquantel 600 mg is a clinically proven, WHO-recommended anthelmintic tablet used to treat a broad range of parasitic worm infections, including schistosomiasis, tapeworms, and liver flukes. Its powerful mechanism of action, high cure rates, and wide safety margin make it a first-line choice in parasitic disease management.When you choose Steris Healthcare Pvt. Ltd., you’re not just selecting a medicine—you’re partnering with a company that prioritizes quality, consistency, regulatory compliance, and nationwide accessibility. With its WHO-GMP certified manufacturing, dedicated customer support, and focus on affordability, Steris Healthcare ensures you get nothing but the best in praziquantel 600 mg tablet solutions.