PIRFENOID 200 & Pirfenidone (200mg) :Benefits , Uses, Side Effects and other Information.

PIRFENOID 200 

Pirfenidone (200mg)

PIRFENOID 200 is a medication primarily used for the treatment of idiopathic pulmonary fibrosis (IPF). This chronic, progressive lung disease leads to scarring of the lung tissues, resulting in severe breathing difficulties and reduced oxygen intake. Pirfenidone, the active ingredient in PIRFENOID 200, has shown promising results in slowing the progression of this debilitating condition.

What is Pirfenidone?

Pirfenidone is an antifibrotic agent that also possesses anti-inflammatory and antioxidant properties. It works by inhibiting the production of transforming growth factor-beta (TGF-β), a protein that plays a crucial role in the formation of scar tissue (fibrosis). By mitigating the effects of TGF-β, Pirfenidone helps to reduce lung scarring and improve lung function in patients with IPF.

Uses of PIRFENOID 200

PIRFENOID 200 is specifically indicated for:

• Idiopathic Pulmonary Fibrosis (IPF): PIRFENOID 200 helps manage and slow the progression of IPF, thereby improving the quality of life for patients.
• Other Fibrotic Conditions: Although primarily used for IPF, Pirfenidone is also being studied for potential benefits in other fibrotic diseases, including systemic sclerosis and chronic liver diseases.

Dosage and Administration

Recommended Dosage

The typical starting dose for PIRFENOID 200 is 200 mg taken orally three times a day. The dosage may be gradually increased to 600 mg per day (200 mg three times a day) based on the patient's tolerance and clinical response.

Administration Guidelines

• With Food: It is recommended to take PIRFENOID 200 with food to minimize gastrointestinal side effects.
• Missed Dose: If a dose is missed, it should be taken as soon as possible unless it is close to the time for the next dose.

Side Effects

Common Side Effects

• Gastrointestinal Issues: Nausea, diarrhea, and indigestion are commonly reported.
• Skin Reactions: Rash and photosensitivity (increased sensitivity to sunlight) can occur, making it advisable to use sunscreen and protective clothing when outdoors.
• Fatigue: Some patients may experience fatigue or weakness.

Serious Side Effects

• Liver Enzyme Elevations: Regular monitoring of liver function tests is recommended, as Pirfenidone can cause elevated liver enzymes.
• Photosensitivity Reaction: Severe sunburn can occur; hence, patients are advised to avoid prolonged sun exposure and use adequate sun protection.

Managing Side Effects

• Gastrointestinal Symptoms: Taking the medication with food can help reduce nausea and other gastrointestinal issues.
• Skin Reactions: Using broad-spectrum sunscreen and wearing protective clothing can mitigate the risk of photosensitivity reactions.
• Regular Monitoring: Regular blood tests to monitor liver function and overall health are essential during treatment.

Precautions and Warnings

Before Taking PIRFENOID 200

• Medical History: Inform your doctor about any history of liver or kidney disease, or if you have any other medical conditions.
• Allergies: Disclose any known allergies to Pirfenidone or other medications.
• Pregnancy and Breastfeeding: The safety of PIRFENOID 200 in pregnant or breastfeeding women has not been established.

Drug Interactions

• CYP1A2 Inhibitors: Avoid concurrent use with strong CYP1A2 inhibitors (e.g., fluvoxamine) as they can increase Pirfenidone levels in the blood.
• CYP1A2 Inducers: Smoking can reduce the effectiveness of Pirfenidone by increasing its metabolism. Patients are advised to quit smoking while on this medication.

Storage and Handling

• Temperature: Store PIRFENOID 200 at room temperature, away from direct sunlight and moisture.
• Keep Out of Reach: Ensure that the medication is kept out of reach of children and pets.
• Expiration: Do not use the medication past its expiration date.

Conclusion

PIRFENOID 200 (Pirfenidone 200 mg) represents a significant advancement in the management of idiopathic pulmonary fibrosis. By slowing the progression of lung scarring, it helps improve the quality of life for patients suffering from this challenging condition. While side effects and precautions need to be carefully considered, the potential benefits of PIRFENOID 200 make it a valuable option in the therapeutic arsenal against IPF.  For more information about PIRFENOID 200, including patient testimonials and the latest research, consider visiting reputable medical websites, patient advocacy groups, and clinical trial databases. Staying informed and engaged with ongoing research can provide valuable insights and support for those managing idiopathic pulmonary fibrosis. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology

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