Oxalobacter Formigenes, Bifidobacterium Lactis, Lactobacillus Acidophilus & Bacillus Coagulans

OXABACTOR is an innovative, multi-strain probiotic capsule developed by Steris Healthcare. This new product is intended to restore the natural balance within the gut microbiota, decrease oxalate in urine, and foster optimal digestion. The capsule contains four clinically proven probiotics including Oxalobacter Formigenes, Bifidobacterium Lactis, Lactobacillus Acidophilus, and Bacillus Coagulans, which have been chosen due to their special functions in the gut ecosystem.

In contrast to the variety of common probiotic capsules available nowadays, OXABACTOR was specifically developed for those who suffer from hyperoxaluria, renal calculi formation, irritable bowel syndrome (IBS), and leaky gut syndrome. Steris Healthcare has taken into consideration recent clinical evidence of the importance of the gut microbiota for oxalate metabolism and calcium regulation.

 

What Is Oxalobacter Formigenes & Bifidobacterium Lactis Used For? 

This is one of the most searched questions in digestive health today — and for good reason. Let's break it down clearly.

Oxalobacter Formigenes: Uses & Benefits

Oxalobacter Formigenes is a gram-negative, anaerobic bacterium that naturally colonizes the human large intestine. It is the only known gut bacterium that uses oxalate as its sole energy source, making it uniquely important for controlling oxalate levels in the body.

Primary uses of Oxalobacter Formigenes include:

• Oxalate degradation: Breaks down dietary oxalate in the colon, reducing the amount absorbed into the bloodstream and subsequently excreted in urine.
• Kidney stone prevention: By lowering urinary oxalate (hyperoxaluria), it directly reduces the risk of calcium oxalate kidney stone formation — the most common type of kidney stone.
• Gut microbiome restoration: Replenishes a key functional bacterium that is often wiped out by antibiotic use, inflammatory bowel disease, or poor diet.
• Reducing oxalate toxicity: Excess oxalate in tissues has been linked to fibromyalgia, autism spectrum disorder (ASD), thyroid dysfunction, and joint pain. Restoring O. Formigenes may help alleviate these symptoms.

Studies show that individuals who are colonized with Oxalobacter Formigenes excrete 70–80% less urinary oxalate compared to those who are not colonized. This statistic alone explains why OXABACTOR by Steris Healthcare centers this bacterium in its formulation.

Bifidobacterium Lactis: Uses & Benefits

Bifidobacterium Lactis (also written as B. lactis) is one of the most researched probiotic strains for digestive and immune health. Its core uses include:

• Improving bowel regularity and reducing constipation
• Enhancing immune response — stimulates production of IgA antibodies
• Reducing gut inflammation — beneficial for IBS and Crohn's disease patients
• Supporting lactose digestion — produces lactase enzyme to break down dairy
• Synbiotic activity with Oxalobacter — creates a gut environment favorable for O. Formigenes colonization

In OXABACTOR, Bifidobacterium Lactis acts as a microbiome scaffold — conditioning the colon environment so that Oxalobacter Formigenes can thrive and perform its oxalate-degrading function more effectively.

 

Key Composition: Understanding Each Strain 

OXABACTOR capsules contain a precisely calibrated blend of four strains:

1. Oxalobacter Formigenes

• Role: Oxalate metabolism, kidney stone prevention
• Mechanism: Enzymatically degrades oxalate via oxalyl-CoA decarboxylase and formyl-CoA transferase
• Target: Hyperoxaluria, recurrent calcium oxalate nephrolithiasis
• Unique property: The only gut bacterium that obligately ferments oxalate

2. Bifidobacterium Lactis

• Role: Gut lining integrity, immune modulation
• Mechanism: Produces short-chain fatty acids (SCFAs) that nourish colonocytes
• Target: IBS, leaky gut, post-antibiotic recovery
• CFU Range in OXABACTOR: Clinically relevant doses as per Steris Healthcare's proprietary formulation

3. Lactobacillus Acidophilus

• Role: Competitive exclusion of pathogens, oxalate co-degradation
• Mechanism: Produces lactic acid and bacteriocins, lowers gut pH to inhibit harmful bacteria
• Target: Vaginal health, urinary tract infections (UTIs), lactose intolerance
• Synergy with O. Formigenes: L. Acidophilus has shown modest oxalate-degrading capacity in clinical research, making it a natural partner strain in OXABACTOR

4. Bacillus Coagulans

• Role: Heat-stable, spore-forming probiotic for gut resilience
• Mechanism: Survives stomach acid and bile salts; germinates in the intestine
• Target: Bloating, diarrhea, abdominal discomfort
• Why it's included in OXABACTOR: Its spore-forming nature ensures survivability through harsh GI environments, acting as a reliable delivery agent for the entire multi-strain matrix

 

How to Increase Oxalobacter Formigenes in the Gut 

This is a critical question — and one Steris Healthcare has specifically addressed in the OXABACTOR formulation. Oxalobacter Formigenes is not naturally present in everyone's gut, and many people lose it entirely due to:

• Antibiotic use (especially broad-spectrum antibiotics like ciprofloxacin and amoxicillin)
• Inflammatory bowel disease (IBD)
• Low dietary oxalate paradoxically reducing selective pressure for O. Formigenes
• Western dietary patterns high in processed food and low in plant fiber
• Proton pump inhibitor (PPI) use

Proven Ways to Increase Oxalobacter Formigenes Levels:

1. Take OXABACTOR Capsules (Direct Supplementation) The most direct and clinically studied method. OXABACTOR by Steris Healthcare delivers live Oxalobacter Formigenes directly to the colon, bypassing gastric acid degradation through its enteric-coated capsule technology.

2. Consume Oxalate-Rich Foods as Substrate O. Formigenes needs oxalate to survive. Moderate consumption of foods like spinach, beets, almonds, and dark chocolate provides the oxalate substrate the bacterium needs to proliferate — but only when combined with probiotic supplementation.

3. Increase Dietary Fiber (Prebiotic Support) Inulin, FOS (fructooligosaccharides), and resistant starch feed beneficial bacteria and support a microbiome environment where O. Formigenes can thrive. Foods like garlic, onion, chicory root, and green bananas are excellent prebiotic sources.

4. Avoid Unnecessary Antibiotics If you've recently completed a course of antibiotics, O. Formigenes is likely depleted. OXABACTOR is specifically designed for post-antibiotic microbiome restoration.

5. Stay Hydrated Adequate water intake (2.5–3L/day) dilutes oxalate in urine and supports the renal clearance environment that makes gut-based oxalate management more effective.

6. Reduce Gut Inflammation A chronically inflamed gut is hostile to O. Formigenes colonization. Address underlying inflammation through anti-inflammatory diet, stress management, and supplementation with the companion strains in OXABACTOR.

 

Where Can I Buy Oxalobacter Formigenes Capsules? 

OXABACTOR capsules are available exclusively through Steris Healthcare's authorized distribution network.

Given the highly specialized nature of Oxalobacter Formigenes as a therapeutic probiotic, it is not available through generic supplement retailers. Steris Healthcare ensures:

• Cold-chain integrity during storage and delivery to maintain CFU viability
• Third-party batch testing for purity, potency, and absence of contaminants
• GMP-certified manufacturing with ISO compliance
• Prescription and OTC channels depending on your regional healthcare regulations

How to Purchase OXABACTOR:

• Through your Urologist or Nephrologist: Ask your specialist to prescribe OXABACTOR if you have a history of calcium oxalate kidney stones or hyperoxaluria
• Through Steris Healthcare's distributor network: Available at leading hospital pharmacies, specialty clinics, and select medical stores
• Online (Coming Soon): Steris Healthcare is expanding its direct-to-consumer digital pharmacy presence — contact us for updates

Note for Healthcare Professionals: Steris Healthcare offers institutional supply contracts for hospitals, urology departments, and nephrology clinics requiring bulk OXABACTOR supply.

 

Oxalobacter Formigenes + Lactobacillus Acidophilus: A Powerful Synergy 

The combination of Oxalobacter Formigenes and Lactobacillus Acidophilus in OXABACTOR is not accidental — it is backed by emerging microbiome science.

Why These Two Strains Work Together:

Complementary Oxalate Metabolism: While O. Formigenes is the primary oxalate degrader, Lactobacillus Acidophilus has demonstrated measurable oxalate-degrading enzyme activity (oxalyl-CoA decarboxylase expression). In OXABACTOR, these two strains create a dual-enzyme system that more comprehensively processes oxalate across different sections of the gut.

Competitive Exclusion of Pathobionts: L. Acidophilus produces lactic acid and hydrogen peroxide, creating an acidic microenvironment that suppresses harmful bacteria (like E. coli and Clostridium species) that compete with or harm O. Formigenes.

Immune Modulation: L. Acidophilus is a well-documented immunomodulator that regulates Th1/Th2 balance and reduces gut inflammation — directly benefiting the colonization success of the more sensitive O. Formigenes.

Urogenital Protection: For female patients prone to recurrent UTIs (often correlated with hyperoxaluria and kidney stone history), Lactobacillus Acidophilus provides added vaginal and urinary tract microbiome protection — a clinical benefit uniquely combined in OXABACTOR.

Oxalobacter Formigenes + Lactobacillus Acidophilus + Lactobacillus Rhamnosus

Some clinical protocols — and the emerging research on Oxalobacter Formigenes, Lactobacillus Acidophilus, and Lactobacillus Rhamnosus combinations — suggest a three-strain approach may offer superior outcomes for:

• Post-bariatric surgery hyperoxaluria
• Inflammatory bowel disease-associated oxalate absorption disorder
• Pediatric primary hyperoxaluria management (adjunctive)

Steris Healthcare continues to monitor this research and may incorporate L. Rhamnosus into future OXABACTOR formulation updates.

 

OXABACTOR for Kidney Stone Prevention: What the Science Says 

Calcium oxalate nephrolithiasis (kidney stones) affects 10–15% of the global population, with recurrence rates exceeding 50% within 5 years. The gut microbiome connection to kidney stone disease has become one of the most exciting areas of urological research.

The Gut-Kidney Axis

Research published in leading nephrology and microbiology journals confirms a direct gut-kidney axis: bacteria in the colon degrade oxalate before it can be absorbed, reducing urinary oxalate load and thereby reducing kidney stone crystallization.

Key findings relevant to OXABACTOR:

• Patients colonized with Oxalobacter Formigenes have 70% lower risk of recurrent calcium oxalate stones
• Bifidobacterium Lactis supplementation has been shown to reduce urinary oxalate in pediatric hyperoxaluria patients
• Multi-strain probiotic therapy (as in OXABACTOR) shows superior outcomes vs. single-strain approaches
• Bacillus Coagulans reduces gut permeability ("leaky gut"), which directly reduces oxalate absorption from the intestine

Who Benefits Most from OXABACTOR for Kidney Stones?

• First-time kidney stone formers seeking prevention
• Recurrent calcium oxalate stone formers
• Post-lithotripsy patients
• Patients with idiopathic hyperoxaluria
• Those on high-oxalate diets (plant-based, raw food diets)
• Post-bariatric (gastric bypass) patients with enteric hyperoxaluria

 

Who Should Take OXABACTOR Capsules? 

OXABACTOR is indicated for:

Condition	Rationale
Recurrent calcium oxalate kidney stones	Direct oxalate reduction via O. Formigenes
Idiopathic hyperoxaluria	Normalizes urinary oxalate excretion
Post-antibiotic microbiome disruption	Restores O. Formigenes and Lactobacillus populations
Irritable Bowel Syndrome (IBS)	B. Lactis and B. Coagulans relieve symptoms
Leaky Gut Syndrome	B. Coagulans and L. Acidophilus restore gut lining integrity
Post-bariatric surgery	Manages enteric hyperoxaluria from increased oxalate absorption
Inflammatory Bowel Disease (adjunctive)	Microbiome restoration support
Fibromyalgia / joint pain (oxalate-related)	Reducing tissue oxalate burden

OXABACTOR is NOT indicated for:

• Children under 3 years (unless under specialist supervision)
• Patients with confirmed immunodeficiency disorders (consult physician)
• Known hypersensitivity to any probiotic strain in the formulation

 

Recommended Dosage & How to Use OXABACTOR 

Standard Adult Dosage:

• 1–2 capsules daily, preferably with meals or as directed by your physician
• For kidney stone prevention: take with the largest meal of the day
• For IBS or post-antibiotic recovery: take 30 minutes before breakfast for optimal colonization

Duration of Use:

• Short-term (4–8 weeks): For post-antibiotic recovery or acute digestive complaints
• Long-term (3–6 months+): For hyperoxaluria, kidney stone prevention, and sustained microbiome restoration
• Maintenance: Once colonization is confirmed (via stool PCR testing for O. Formigenes), a maintenance dose of 1 capsule/day may be sufficient

Storage: Store in a cool, dry place (below 25°C). Refrigeration recommended after opening for maximum CFU viability.

 

Are There Any Side Effects? 

OXABACTOR is generally well-tolerated. As with any probiotic supplement, some individuals may experience:

Mild & Transient (first 3–5 days):

• Mild bloating or gas
• Slight change in bowel frequency
• Loose stools or temporary constipation

Rare:

• Mild nausea (take with food to minimize)
• In immunocompromised patients — consult physician before use

No serious adverse events have been reported with properly dosed multi-strain probiotic therapy using these four strains. Steris Healthcare's OXABACTOR undergoes rigorous safety testing per GMP and regulatory standards.

 

Why Choose Steris Healthcare? 

Steris Healthcare is a dedicated pharmaceutical innovation company committed to developing science-backed, clinically relevant therapeutic formulations that address unmet medical needs. OXABACTOR represents our expertise at the intersection of nephrology, gastroenterology, and microbiome medicine.

Our Commitment:

• Rigorous R&D: Every Steris Healthcare formulation is backed by peer-reviewed clinical data and developed by a team of pharmacologists, gastroenterologists, and nephrologists.
• GMP Manufacturing: All Steris Healthcare products are manufactured in GMP-certified facilities with ISO quality standards.
• Patient-Centric Design: OXABACTOR is designed not just for efficacy but for real-world tolerability — enteric-coated capsules, precise dosing, and a stable formulation that survives the journey to your gut.
• Physician Partnership: Steris Healthcare works directly with nephrologists, urologists, and gastroenterologists to ensure OXABACTOR is part of evidence-based clinical protocols.
• Transparency: Full composition disclosure, third-party batch reports, and comprehensive patient information — because you deserve to know exactly what you're putting in your body.

 

Conclusion

Oxabactor from Steris Healthcare is more than just an ordinary probiotic capsule. This is a specially designed combination of different strains of probiotics revolving around the research on Oxalobacter Formigenes, which current medicine acknowledges as the primary key for prevention of kidney stones, regulation of oxalates and the healthy gut bacteria balance.

Alongside with Bifidobacterium Lactis, Lactobacillus Acidophilus and Bacillus Coagulans, Oxabactor provides the necessary probiotics mix for solving the problems associated with hyperoxaluria, kidney stones, irritable bowel syndrome, leaky gut syndrome and post-antibiotic dysbiosis.

If you experience problems with recurrent kidney stones, high levels of oxalates in urine or other gut-related issues — contact your urologist, nephrologist or gastroenterologist today about Oxabactor by Steris Healthcare.

 

Frequently Asked Questions 

What is Oxalobacter Formigenes Bifidobacterium Lactis used for?

Together, these two strains work to degrade oxalate in the gut (O. Formigenes) and restore gut barrier integrity and immune balance (B. Lactis). Their combined use in OXABACTOR is particularly indicated for hyperoxaluria, kidney stone prevention, IBS, and post-antibiotic microbiome restoration.

Where can I buy Oxalobacter Formigenes supplements in India?

OXABACTOR by Steris Healthcare is available through authorized medical distributors, specialty hospital pharmacies, and urology/nephrology clinics across India. Due to the specialized nature of O. Formigenes, it is not available through generic OTC pharmacy channels. Contact Steris Healthcare directly or ask your urologist to prescribe OXABACTOR.

How do I know if I am deficient in Oxalobacter Formigenes?

A stool microbiome PCR test (available through specialty diagnostic labs) can detect the presence or absence of O. Formigenes in your gut. Clinically, if you have recurrent calcium oxalate kidney stones, elevated urinary oxalate (>40 mg/day), or have taken antibiotics in the past 6 months — you are likely deficient.

Can OXABACTOR replace medical treatment for kidney stones?

No. OXABACTOR is a complementary/preventive probiotic therapy. It is not a substitute for acute medical management of kidney stones, which may require urological intervention, lithotripsy, or surgery. Always consult your nephrologist or urologist regarding treatment planning.

How long does it take for Oxalobacter Formigenes to colonize the gut?

Studies suggest that consistent O. Formigenes supplementation shows measurable reductions in urinary oxalate within 4–8 weeks of daily use. Full colonization and gut establishment may require 3–6 months of consistent use.

Is OXABACTOR safe during pregnancy?

Pregnant and breastfeeding women should consult their obstetrician before starting any probiotic supplement, including OXABACTOR. The individual strains (L. Acidophilus, B. Lactis) have established safety profiles in pregnancy, but clinical guidance from your doctor is essential.

Can OXABACTOR help with oxalate-related fibromyalgia or joint pain?

Emerging evidence links elevated tissue and urinary oxalate to musculoskeletal pain syndromes, including fibromyalgia. Reducing oxalate burden through O. Formigenes-based supplementation like OXABACTOR may contribute to symptomatic relief, though this remains an area of active research. Steris Healthcare recommends discussing this use case with a rheumatologist.

What is the difference between Oxalobacter Formigenes and Lactobacillus Acidophilus in terms of oxalate degradation?

Oxalobacter Formigenes is an obligate oxalate degrader — it depends entirely on oxalate for energy. Lactobacillus Acidophilus is a facultative oxalate degrader — it can degrade oxalate using the same enzymatic pathway but does not exclusively depend on it. In OXABACTOR, this means O. Formigenes handles the majority of oxalate degradation, while L. Acidophilus provides supplementary enzymatic activity and broader microbiome support.

Does OXABACTOR need refrigeration?

Store below 25°C in a cool, dry place. Refrigeration after opening is recommended to maximize CFU viability. Do not freeze. Keep away from direct sunlight and humidity.

Is OXABACTOR vegetarian/vegan?

Steris Healthcare formulates OXABACTOR with a focus on broad patient accessibility. Capsule shell details (HPMC vegetarian vs. gelatin) are available on the product packaging. Contact Steris Healthcare for formulation-specific queries.