Mesalazine (1g) g

Introduction

MESALMILE 1 is a premium formulation containing mesalazine 1 g in the form of pellets, developed to effectively manage and treat inflammatory bowel conditions like ulcerative colitis, Crohn’s disease, and proctitis. Manufactured by Steris Healthcare, this product provides targeted anti-inflammatory action directly in the colon, reducing symptoms like diarrhea, rectal bleeding, and abdominal pain.

Composition

• Each sachet of MESALMILE 1 contains:

  • Mesalazine IP 1g (1000 mg) Pellets

What is Mesalazine?

Mesalazine (also called mesalamine or 5-aminosalicylic acid / 5-ASA) is an anti-inflammatory drug used primarily in the management of inflammatory bowel diseases (IBD). It works locally in the intestine to reduce inflammation and maintain remission in chronic conditions.

Uses of MESALMILE 1 (Mesalazine Pellets 1g Sachet)

MESALMILE 1 is prescribed for:

• Ulcerative Colitis (mild to moderate cases)

• Maintenance of remission in ulcerative colitis

• Crohn’s Disease (especially colonic involvement)

• Proctitis and Proctosigmoiditis

• IBD-related symptoms such as diarrhea, rectal bleeding, abdominal cramps

• Pouchitis post-surgery in IBD patients

How MESALMILE 1 Works

Mesalazine acts locally in the lining of the colon by inhibiting cyclooxygenase and lipoxygenase pathways, reducing the production of inflammatory mediators like prostaglandins and leukotrienes. The pellet formulation ensures targeted drug release in the colon, minimizing systemic side effects and maximizing therapeutic action where it's needed most.

Dosage and Administration

• Adults (usual dose): 1g to 2g once or twice daily, as directed by the physician.

• MESALMILE 1 is available in sachet form containing mesalazine pellets which can be swallowed or sprinkled on soft food.

• Do not chew the pellets. Swallow whole for proper release.

Always follow the dosing instructions provided by your healthcare provider.

Side Effects of Mesalazine 1g

While MESALMILE 1 is generally well tolerated, some individuals may experience:

• Headache

• Nausea or abdominal pain

• Flatulence

• Diarrhea

• Rash or skin reactions

• Rare: blood disorders, kidney problems, pancreatitis, or liver enzyme elevation

Seek immediate medical help if you experience signs of allergic reaction, such as rash, itching, swelling, or breathing difficulty.

Precautions Before Using MESALMILE 1

• Inform your doctor if you have kidney or liver disease.

• Use cautiously in patients with peptic ulcers or allergy to salicylates (like aspirin).

• Regular monitoring of renal function is advised during long-term use.

• Safe use in pregnancy and breastfeeding should be discussed with a doctor.

Drug Interactions

Mesalazine may interact with:

• Azathioprine or 6-mercaptopurine – may increase bone marrow suppression risk

• NSAIDs – may increase nephrotoxicity risk

• Antacids or proton pump inhibitors – may affect drug release from coated pellets

Why Choose MESALMILE 1 by Steris Healthcare?

• Targeted Pellet Technology for colon-specific release

• Reliable relief from inflammatory bowel symptoms

• GMP-WHO certified manufacturing standards

• Safe for long-term use in maintenance therapy

• Prescribed by leading gastroenterologists

• Backed by Steris Healthcare, a name trusted in GI and chronic care therapeutics

FAQs About MESALMILE 1 (Mesalazine 1g Sachet)

Q1. Can MESALMILE 1 cure ulcerative colitis?

A: No, ulcerative colitis is a chronic condition. MESALMILE 1 helps manage symptoms and maintain remission but is not a cure.

Q2. Is MESALMILE 1 safe for long-term use?

A: Yes, under medical supervision, it is safe for long-term maintenance of remission in IBD.

Q3. Can I mix MESALMILE 1 pellets with food?

A: Yes, you may sprinkle the pellets over soft food or yogurt, but do not chew the pellets.

Q4. Does MESALMILE 1 have steroids?

A: No, it contains mesalazine, an anti-inflammatory drug, not a steroid.

Q5. When can I expect symptom relief?

A: Most patients notice improvement within a few days to weeks of starting therapy.

Conclusion

MESALMILE 1 is an advanced, gastroenterologist-recommended treatment for ulcerative colitis and other inflammatory bowel conditions. With its colon-targeted mesalazine 1g pellet formulation, it provides focused relief and long-term remission support. Choose MESALMILE 1 by Steris Healthcare for reliable, safe, and effective IBD care.