Mefenamic Acid With Paracetamol Suspension Effective Relief for Pain and Fever in Kids Steris Healthcare.

Dec 13, 2025

Managing pain and fever in children is a common concern for parents and healthcare providers alike. Pediatric-friendly medications that are both safe and effective are crucial for timely relief and comfort. METAPECT MF KID SUSPENSION combines Mefenamic Acid and Paracetamol, offering a dual-action approach to reduce fever and alleviate mild to moderate pain in children.

Formulated for pediatric use, this suspension provides fast relief while being well-tolerated by most children. This comprehensive guide covers everything about METAPECT MF KID SUSPENSION, including composition, mechanism, uses, dosage, safety, and parental guidance.

Definition of METAPECT MF KID SUSPENSION

METAPECT MF KID SUSPENSION is an oral liquid medicine specifically designed for children. It is a combination of Mefenamic Acid and Paracetamol that works synergistically to manage fever and various types of pain in pediatric patients. The suspension format makes it easier for children to ingest while ensuring accurate dosing.

Composition

Each 5 ml of METAPECT MF KID SUSPENSION contains:

  • Mefenamic Acid: Non-steroidal anti-inflammatory drug (NSAID) that reduces inflammation, pain, and fever.

  • Paracetamol: Analgesic and antipyretic that works centrally to lower fever and relieve mild pain.

Other inactive ingredients include flavoring agents and stabilizers to ensure palatability and stability of the suspension.

Therapeutic Class

METAPECT MF KID SUSPENSION belongs to the analgesic and antipyretic combination class. It combines the benefits of an NSAID and a central analgesic for comprehensive symptom control.

Mechanism of Action

Mefenamic Acid

Mefenamic Acid works by inhibiting prostaglandin synthesis via cyclooxygenase (COX) enzymes. This results in:

  • Reduction of pain perception

  • Anti-inflammatory effects

  • Fever reduction by acting on hypothalamic thermoregulatory centers

Paracetamol

Paracetamol works primarily in the central nervous system by:

  • Inhibiting prostaglandin synthesis in the brain

  • Modulating the heat-regulating center to lower fever

  • Relieving mild to moderate pain without significant anti-inflammatory effects

The combination ensures both rapid and sustained relief from fever and pain.

Indications

Fever Reduction

METAPECT MF KID SUSPENSION is highly effective in reducing elevated body temperature caused by infections or post-vaccination reactions.

Pain Relief

Indicated for:

  • Headaches

  • Dental pain

  • Menstrual discomfort (in older pediatric patients)

  • Muscle and joint pain

Pediatric Use and Dosing Guidelines

For children, dosage is calculated based on weight and age, ensuring safety and efficacy. Always follow the physician’s instructions:

  • Shake the suspension well before use

  • Measure the dose using a calibrated measuring spoon or syringe

  • Avoid administering more than recommended doses within 24 hours

Typical pediatric dosing ranges from 5 mg/kg to 10 mg/kg per day, divided into multiple doses.

Adult Use and Recommended Dosage

While primarily for children, older adolescents may be prescribed METAPECT MF KID SUSPENSION under supervision. The dosage must be carefully adjusted based on body weight and overall health condition.

Onset of Action and Duration of Effect

  • Paracetamol: Rapid onset within 30–60 minutes; effect lasts 4–6 hours

  • Mefenamic Acid: Onset within 30–60 minutes; anti-inflammatory effect lasts up to 6–8 hours

This combination ensures quick relief and prolonged effect, reducing the need for frequent dosing.

Benefits of Combination Therapy Over Monotherapy

  • Enhanced pain relief by targeting both peripheral and central pathways

  • Faster fever reduction

  • Reduced need for multiple medications

  • Improved compliance due to a single, palatable formulation

Role in Managing Mild to Moderate Pain

METAPECT MF KID SUSPENSION effectively manages:

  • Post-dental procedure pain

  • Muscle aches

  • Headaches

  • Mild joint discomfort

Role in Managing Post-Vaccination Fever

Children often experience mild fever after vaccinations. This suspension provides:

  • Rapid fever control

  • Comfort and symptom relief

  • Safe administration with weight-appropriate dosing

Advantages in Pediatric Care

  • Oral suspension suitable for children who cannot swallow tablets

  • Palatable flavor to encourage compliance

  • Single-dose combination reduces medication errors

Safety Profile and Tolerability in Children

Generally well-tolerated when administered at recommended doses:

  • Most children experience no adverse effects

  • Mild side effects such as nausea or mild stomach upset may occur

Common Side Effects

  • Nausea

  • Mild stomach upset

  • Temporary headache or dizziness

Rare Side Effects and Precautions

  • Allergic reactions (rash, itching, swelling)

  • Gastrointestinal bleeding in very rare cases

  • Liver or kidney impairment in prolonged overdose situations

  • Always consult a pediatrician if symptoms persist

Drug Interactions and Contraindications

  • Avoid concomitant use with other NSAIDs to prevent additive toxicity

  • Monitor if used with anticoagulants or medications affecting liver function

  • Contraindicated in known hypersensitivity to Mefenamic Acid or Paracetamol

Pregnancy and Breastfeeding Considerations

METAPECT MF KID SUSPENSION is not recommended for use in pregnant or breastfeeding women without medical guidance.

Administration Tips

  • Shake well before each use to ensure uniform dosing

  • Administer with or without food

  • Use the provided dosing spoon or syringe for accuracy

Storage Instructions

  • Store at 25°C or below, away from direct sunlight

  • Keep out of reach of children

  • Do not freeze the suspension

Importance of Adherence to Prescribed Dosage

  • Prevents overdose and toxicity

  • Ensures consistent therapeutic effect

  • Reduces risk of side effects

Avoiding Overdose and Toxicity Risks

  • Do not exceed recommended daily dose

  • Avoid concurrent administration with other paracetamol-containing products

  • Seek immediate medical attention if overdose occurs

Use in Combination with Other Antipyretics: Safety Considerations

  • Avoid simultaneous use with other NSAIDs

  • Paracetamol co-administration should be monitored to prevent excessive daily intake

Role in Reducing Inflammation

Mefenamic Acid provides anti-inflammatory benefits by:

  • Reducing prostaglandin synthesis at the site of inflammation

  • Alleviating swelling and localized pain

  • Complementing Paracetamol’s central analgesic effect

Over-the-Counter Availability and Prescription Guidelines

  • Available under the brand METAPECT MF KID SUSPENSION

  • May require prescription depending on local regulations

  • Parents should always follow pediatrician guidance

Pediatric-Friendly Flavors and Formulations

  • Developed with child-friendly flavors to improve compliance

  • Suspension form allows precise dose measurement

  • Easy to administer for children who dislike tablets

Monitoring for Allergic Reactions

  • Observe for rash, itching, swelling, or breathing difficulty

  • Seek immediate medical attention if severe allergic reaction occurs

Clinical Efficacy and Studies Supporting Combination Use

  • Multiple clinical trials support the synergistic effect of Mefenamic Acid with Paracetamol for pediatric pain and fever

  • Combination therapy reduces the frequency and intensity of symptoms more effectively than monotherapy

  • Well-documented safety profile in children aged 2–12 years

Conclusion

METAPECT MF KID SUSPENSION is a safe, effective, and pediatric-friendly solution for managing pain and fever. Combining the analgesic and anti-inflammatory properties of Mefenamic Acid with the central antipyretic effect of Paracetamol, it offers rapid and sustained relief. Proper dosing, adherence to physician instructions, and awareness of safety precautions ensure the best outcomes for children’s comfort and health.

FAQs and Parental Guidance for Safe Use

Q1: Can METAPECT MF KID SUSPENSION be given on an empty stomach?
A: Yes, but giving it with food may reduce mild stomach upset.

Q2: How often can the suspension be administered?
A: Typically every 6–8 hours, not exceeding 4 doses in 24 hours.

Q3: Is it safe for children under 2 years?
A: Consult a pediatrician; use is generally recommended for children 2 years and above.

Q4: Can it be used for post-vaccination fever?
A: Yes, with proper dosing as advised by a physician.

Q5: What should be done in case of missed dose?
A: Administer as soon as possible; do not double the next dose.

 

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