Lenalidomide 25 mg Tablet: View Uses, Benefits, Dosage, Side Effects.

Jul 29, 2025

Lenalidomide 25 mg Tablet is a powerful and widely prescribed medication primarily used in the treatment of certain types of blood cancers and anemia-related conditions. As a derivative of thalidomide, Lenalidomide possesses both immunomodulatory and antiangiogenic properties, making it highly effective in managing complex diseases such as multiple myeloma, myelodysplastic syndromes, and mantle cell lymphoma. It is an anti-cancer medication, It is used in the treatment of multiple myeloma and myelodysplastic syndrome.  

What is Lenalidomide 25 mg?

Lenalidomide 25 mg is an oral medication belonging to the class of immunomodulatory drugs. It modifies the immune system's response and affects the development of blood vessels that tumors need to grow. Tab Lenalidomide 25 mg is primarily used in combination with other medications like dexamethasone for effective cancer therapy.
 

Lenalidomide 25 mg Uses

The main Lenalidomide 25 mg uses include:

1. Multiple Myeloma

One of the most common uses of Lenalidomide 25 mg is for treating multiple myeloma, a cancer of the plasma cells in the bone marrow. It is usually combined with corticosteroids like dexamethasone for a more robust response.

2. Myelodysplastic Syndromes (MDS)

Lenalidomide is indicated for the treatment of anemia associated with low or intermediate-1-risk MDS, particularly those with deletion 5q cytogenetic abnormality. It improves red blood cell production and reduces the need for blood transfusions.

3. Mantle Cell Lymphoma (MCL)

4. Follicular and Marginal Zone Lymphoma

Though off-label in some regions, Lenalidomide is sometimes prescribed for follicular lymphoma and marginal zone lymphoma in specific clinical settings.
 

Key Benefits of Lenalidomide 25 mg Tablet

  • Improves Survival Rates: In cancers like multiple myeloma, it significantly enhances survival when used in maintenance therapy.

  • Reduces Transfusion Needs: In MDS patients, it reduces or eliminates the need for frequent blood transfusions.

  • Convenient Oral Administration: Unlike many cancer therapies, tab Lenalidomide 25 mg is taken orally, making it more convenient for long-term use.

  • Immunomodulation: Enhances the immune system's ability to fight abnormal or cancerous cells.

  • Antiangiogenic Properties: Inhibits the growth of new blood vessels needed by tumors.

 

Recommended Dosage and Administration

The dosage of Lenalidomide 25 mg tablets depends on the medical condition, patient tolerance, and accompanying therapies. However, the general dosage guidelines are:

  • Multiple Myeloma: 25 mg once daily on Days 1–21 of repeated 28-day cycles, typically used in combination with dexamethasone.

  • MDS: Usually 10 mg once daily, continuously or as recommended by the oncologist.

  • Mantle Cell Lymphoma: 25 mg once daily on Days 1–21 of 28-day cycles.

Important: Always follow your healthcare provider’s prescription. Dose adjustments may be needed for patients with kidney impairment or in cases of side effects.

 

Possible Side Effects of Lenalidomide 25 mg

Like all potent medications, Lenalidomide 25 mg tablets may lead to side effects. These can range from mild to severe:

Common Side Effects:

  • Fatigue

  • Diarrhea

  • Constipation

  • Low white blood cell count (neutropenia)

  • Low platelet count (thrombocytopenia)

  • Muscle cramps

  • Skin rash

Serious Side Effects:

  • Blood clots

  • Liver toxicity

  • Allergic reactions

  • Secondary cancers (rare)

  • Tumor lysis syndrome

Patients on tab lenalidomide 25 mg must be regularly monitored through blood tests to ensure early detection and management of any adverse effects.

 

Safety Precautions

  • Pregnancy Warning: Lenalidomide is highly teratogenic. Women of childbearing age must use two reliable methods of contraception.

  • Regular Monitoring: Frequent blood counts, liver function tests, and renal function monitoring are essential.

  • Drug Interactions: Inform your doctor about all other medications, including supplements and herbal products.

  • Not Recommended for Children: Lenalidomide is not approved for pediatric use.

Lenalidomide 25 mg Price in India

The Lenalidomide 25 mg price varies depending on the manufacturer, location, and brand. Generic versions make it more affordable for patients in India. On average, a strip of 10 tablets may cost between INR 3000 to INR 6000, depending on the brand.

Steris Healthcare and other reputed pharmaceutical companies offer quality-assured Lenalidomide 25 mg tablets at competitive prices, helping to reduce the economic burden of long-term cancer care.

 

Why Choose Quality Brands Like Steris Healthcare?

When dealing with critical conditions like cancer, the quality and consistency of medication are non-negotiable. Trusted companies like Steris Healthcare offer:

  • WHO-GMP certified manufacturing facilities

  • Stringent quality control protocols

  • Affordable pricing with assured availability

  • Reliable support for hospitals, clinics, and patients

SHARE WITH