Cilostazol 50: Mechanism, Dosage, Side Effects & Patient FAQs

Oct 02, 2025

Cilostazol 50 is an effective medication primarily used to improve symptoms of intermittent claudication, a condition characterized by pain and cramping in the legs caused by poor blood circulation. The cilostazol 50 mg tablet activates certain enzymes that help increase blood flow, making it easier to walk longer without pain. If you are looking for a trusted option, CILOSTAZONE 50 by Steris Healthcare offers a reliable and high-quality formulation of this important drug.

What is Cilostazol 50?

Cilostazol 50 mg tablet is a prescription medication classified as a phosphodiesterase III inhibitor. It’s used to increase blood flow in the legs by widening blood vessels and reducing the stickiness of platelets (clot-forming blood cells).

By enhancing blood circulation, tab cilostazol 50 helps reduce pain, cramps, and fatigue during walking caused by narrowed arteries. It improves oxygen delivery to muscles, allowing patients to walk longer and more comfortably.

Cilostazol 50 mg Tablet Uses

The main cilostazol 50 mg tablet uses include:

  • Treatment of intermittent claudication to improve walking distance

  • Enhancement of blood flow by dilating arteries in the legs

  • Prevention of platelet aggregation, reducing clot risk

  • Suitable as a starting dose or dose adjustment for patients sensitive to higher strengths

Tab cilostazol 50 is commonly prescribed to patients who are elderly, have kidney/liver concerns, or are prone to medication side effects.

Cilostazol Drug Class

Cilostazol belongs to the antiplatelet and vasodilator drug class. It works differently from conventional blood thinners by focusing on enhancing arterial blood flow while reducing the risk of clot formation.

Cilostazol Mechanism of Action

The mechanism of action of cilostazol involves inhibiting phosphodiesterase III (PDE3) enzymes in platelets and blood vessel walls. This leads to:

  • Reduced platelet aggregation (lowering clot risk)

  • Dilation of blood vessels to improve circulation

  • Enhanced oxygen and nutrient delivery to leg muscles

  • Reduced pain and discomfort during walking

Through these effects, cilostazol 50 helps patients manage PAD symptoms and improve daily activity levels.

Cilostazol Dose: When to Use 50 mg

Most patients are started on 100 mg twice daily, but for some, starting with tab cilostazol 50 twice a day is preferred.

Cilostazol dose recommendations:

  • Starting dose: 50 mg twice daily in sensitive patients

  • Maintenance dose: May increase to 100 mg twice daily, depending on tolerance and doctor’s advice

  • Take at least 30 minutes before or 2 hours after meals

Your doctor will determine the right dose based on your age, health condition, and how well your body handles the medication.

Benefits of Cilostazol 50 mg (CILOSTAZONE 50)

Using CILOSTAZONE 50 may offer several benefits, especially if you're new to cilostazol or prone to side effects:

  • Improves pain-free walking distance

  • Reduces cramping and fatigue in the legs

  • Enhances circulation without needing surgery

  • Lower risk of side effects at reduced dose

  • Safe initiation of long-term treatment for PAD

Choosing cilostazol 50 mg is often the right first step toward restoring mobility and preventing complications like ulcers or infections in patients with poor limb circulation.

Cilostazol Side Effects

Even at a lower dose, cilostazol may cause side effects in some individuals.

Common side effects:

  • Headache

  • Diarrhea

  • Dizziness

  • Palpitations (fast heart rate)

  • Mild nausea

Rare side effects:

  • Chest pain

  • Swelling in legs

  • Low blood pressure

If you experience any serious symptoms or side effects that persist, inform your doctor immediately.

Who Should Avoid Cilostazol?

Cilostazol 50 mg is not recommended in the following cases:

  • Patients with congestive heart failure

  • Those with uncontrolled arrhythmias

  • Bleeding disorders

  • Pregnant or breastfeeding women (unless prescribed)

Why Choose Steris Healthcare’s CILOSTAZONE 50?

Steris Healthcare is a reliable pharmaceutical brand committed to producing affordable, high-quality medications backed by science and patient safety.

Reasons to trust CILOSTAZONE 50:

  • Manufactured under GMP-certified standards

  • Consistent purity and bioavailability

  • Ideal for dose initiation or adjustment

  • Prescribed widely by vascular and heart specialists

  • Affordable and accessible across pharmacies

Steris Healthcare ensures that you get a trusted, effective formulation of cilostazol 50 mg tablet to manage your condition safely.

Frequently Asked Questions

1. How long does cilostazol 50 take to work?

It may take 2–4 weeks to notice improvements in walking distance. Full results can take up to 12 weeks.

2. Can I take cilostazol 50 with food?

It’s recommended to take cilostazol on an empty stomach—either 30 minutes before or 2 hours after meals to avoid side effects and improve absorption.

3. Can I start directly with cilostazol 100 mg?

Some patients may tolerate 100 mg, but starting with cilostazol 50 helps reduce side effects, especially in the elderly or those with health conditions.

4. Is cilostazol 50 a blood thinner?

Yes, cilostazol has antiplatelet effects, helping prevent clot formation, but it’s different from traditional anticoagulants like warfarin.

5. Is long-term use of cilostazol safe?

Yes, under a doctor’s supervision, cilostazol is safe for long-term use in managing chronic peripheral vascular disease.

Conclusion

Cilostazol 50 is a reliable and effective option for improving blood flow and reducing symptoms of PAD and intermittent claudication. By enhancing circulation and preventing platelet aggregation, it helps patients walk longer distances comfortably. With proper use under medical supervision, cilostazol 50 mg tablets can significantly improve mobility and quality of life while minimizing risks.

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