Ambrisentan Tadalafil Dose, Uses & Side Effects

Sep 22, 2025

Living with pulmonary arterial hypertension (PAH) can be challenging, but medical science now offers effective treatment options to help patients live more comfortably. One of the most trusted therapies is the ambrisentan tadalafil combination, which combines two powerful medicines – Ambrisentan 5 mg and Tadalafil 20mg – in a single regimen.

The tab ambrisentan tadalafil therapy is prescribed by doctors worldwide to reduce high blood pressure in the lungs, improve oxygen flow, and help patients regain stamina. By targeting PAH with dual mechanisms, this combination provides stronger results than using either medicine alone.

What is Tab Ambrisentan Tadalafil?

The tab ambrisentan tadalafil is a prescription combination used in patients suffering from pulmonary arterial hypertension.

  • Ambrisentan 5 mg: An endothelin receptor antagonist that prevents blood vessels in the lungs from narrowing.

  • Tadalafil 20mg: A PDE-5 inhibitor that relaxes blood vessels and improves blood circulation.

When taken together, ambrisentan + tadalafil help reduce pulmonary pressure, enhance exercise capacity, and improve overall quality of life.

Uses of Ambrisentan + Tadalafil

Patients prescribed tab ambrisentan tadalafil benefit in multiple ways:

  • Reduction in shortness of breath

  • Increased exercise tolerance

  • Slowed progression of pulmonary hypertension

  • Better oxygen supply to vital organs

  • Improved daily activity and overall wellness

How Does Ambrisentan Tadalafil Work?

The combination uses two pathways to combat PAH:

  1. Ambrisentan 5 mg works by blocking endothelin, a natural chemical that tightens blood vessels.

  2. Tadalafil 20mg helps relax smooth muscles in pulmonary arteries, keeping them open and improving oxygen flow.

Together, the ambrisentan + tadalafil therapy reduces strain on the heart and lungs, making it easier for patients to breathe and stay active.

Ambrisentan Tadalafil Dose

Doctors usually recommend:

  • Ambrisentan tadalafil dose: 5 mg Ambrisentan + 20 mg Tadalafil once daily (as in AMBRISTAR 5 + DURA 20 COMBO).

  • The dose may be adjusted based on patient condition and tolerance.

Important note: Never change or stop your ambrisentan tadalafil dose without consulting your healthcare provider.

Side Effects of Tab Ambrisentan Tadalafil

Like all medicines, tab ambrisentan tadalafil may cause some side effects:

Common effects:

  • Headache

  • Flushing

  • Stuffy nose

  • Swelling in ankles/feet

  • Dizziness

Rare but serious effects:

  • Low blood pressure

  • Liver enzyme changes (requires monitoring)

  • Anemia

  • Blurred vision or sudden changes in eyesight

Always inform your doctor if symptoms worsen or persist.

Precautions Before Taking Ambrisentan + Tadalafil

  • Not suitable for pregnant or breastfeeding women.

  • Avoid combining with nitrates or strong blood pressure medicines.

  • Inform your doctor if you have liver or kidney issues.

  • Avoid alcohol, which may worsen dizziness or low blood pressure.

  • Regular monitoring of blood pressure, hemoglobin, and liver function is necessary during treatment.

Why Choose AMBRISTAR 5 + DURA 20 (COMBO) from Steris Healthcare?

Steris Healthcare ensures that patients receive high-quality, affordable, and effective medicines. Choosing this trusted brand guarantees:

  • WHO-GMP certified facilities

  • Reliable safety standards

  • Affordable pricing for all patients

  • Nationwide distribution for easy availability

  • A trusted reputation among healthcare professionals

With AMBRISTAR 5 + DURA 20 (COMBO), patients receive world-class treatment tailored for better PAH management.

Frequently Asked Questions

Q1: What is tab ambrisentan tadalafil used for?
It is prescribed for pulmonary arterial hypertension (PAH) to lower blood pressure in the lungs and improve physical stamina.

Q2: What is the recommended ambrisentan tadalafil dose?
Most patients start with Ambrisentan 5 mg + Tadalafil 20mg once daily, but dosage may vary based on medical advice.

Q3: Can I take tadalafil 20mg separately instead of the combo?
While tadalafil 20mg alone is used for certain conditions, the ambrisentan + tadalafil combination provides stronger results in PAH by targeting two pathways.

Q4: Is ambrisentan 5 mg safe for long-term use?
Yes, when prescribed and monitored by a doctor, ambrisentan 5 mg is safe for long-term management.

Q5: Can I stop tab ambrisentan tadalafil if I feel better?
No. Always consult your doctor before making any changes, as stopping suddenly may worsen PAH.

Final Thoughts

The ambrisentan tadalafil combination has become a life-changing therapy for many patients battling pulmonary arterial hypertension. With AMBRISTAR 5 + DURA 20 (COMBO), you can expect improved breathing, greater energy, and a better quality of life under medical supervision.

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