Ademetionine 200 mg: Elevating Mood & Reducing Depression Naturally

Feb 26, 2025

Product Overview

ADENOSOLE M 200 contains Ademetionine 200 mg, also known as S-Adenosyl-L-Methionine (SAMe), a naturally occurring compound involved in several essential biochemical processes in the human body. It plays a vital role in methylation reactions, neurotransmitter synthesis, glutathione production, and cellular detoxificationADENOSOLE M 200 is used as a supportive therapy in liver diseases, major depressive disorders, and osteoarthritis. It is widely recognized for its hepatoprotective, mood-enhancing, and anti-inflammatory properties.

Composition Detail

  • Ademetionine (S-Adenosyl-L-Methionine) – 200 mg
    Each tablet delivers a stable and bioavailable form of Ademetionine, formulated for optimal absorption and efficacy.

Mechanism of Action

Ademetionine works by participating in three key biochemical pathways:

  1. Methylation:
    SAMe acts as a universal methyl donor for DNA, proteins, phospholipids, and neurotransmitters, essential for mood regulation and cellular function.

  2. Transsulfuration:
    Enhances synthesis of glutathione, a critical antioxidant that supports liver detoxification and protection against oxidative damage.

  3. Aminopropylation:
    Facilitates the synthesis of polyamines, which promote cell regeneration, tissue repair, and cartilage health.

Therapeutic Uses of ADENOSOLE M 200

1. Liver Disorders

  • Fatty liver disease (NAFLD and NASH)

  • Alcoholic liver disease

  • Intrahepatic cholestasis (including during pregnancy)

  • Hepatitis and cirrhosis

  • Elevated liver enzymes (SGOT, SGPT, ALP)

2. Mental Health Support

  • Major depressive disorder (MDD)

  • Treatment-resistant depression (as adjunct therapy with SSRIs or SNRIs)

  • Depression with comorbid liver conditions

3. Joint and Musculoskeletal Health

  • Osteoarthritis (improves cartilage matrix and reduces inflammation)

  • Degenerative joint conditions

Dosage and Administration

  • Typical dose: 200 mg to 800 mg per day in divided doses

  • Best taken on an empty stomach, preferably in the morning

  • Dosage should be adjusted based on the patient’s clinical condition and doctor's recommendation

Advantages of ADENOSOLE M 200

  • High bioavailability formulation of Ademetionine

  • Multi-organ support: liver, brain, and joints

  • Well-tolerated in long-term therapy

  • Scientifically backed by global clinical studies

  • Manufactured under WHO-GMP quality standards

Side Effects

Ademetionine is generally well-tolerated. However, some patients may experience:

  • Mild nausea or stomach discomfort

  • Anxiety or restlessness

  • Insomnia (especially if taken in the evening)

  • Headache

Most side effects are mild and transient.

Precautions

  • Use cautiously in patients with bipolar disorder (risk of mania)

  • Not recommended in first trimester of pregnancy without medical advice

  • Avoid taking with levodopa unless monitored

  • Patients on antidepressants should use under doctor supervision due to risk of serotonin syndrome

  • Use with caution in renal or hepatic impairment

Drug Interactions

  • May enhance the effects of SSRIs, SNRIs, and tricyclic antidepressants

  • Avoid co-administration with monoamine oxidase inhibitors (MAOIs) without medical oversight

  • Interaction with levodopa may reduce its effectiveness

Storage Instructions

  • Store in a cool, dry place below 25°C

  • Protect from light and moisture

  • Keep out of reach of children

Conclusion

ADENOSOLE M 200 offers a clinically validated, high-quality form of Ademetionine 200 mg to support liver function, stabilize mood, and improve joint flexibility. Its triple benefit across hepatology, psychiatry, and rheumatology makes it a versatile therapeutic supplement for long-term health management.Whether prescribed for liver detoxification, mental well-being, or joint support, ADENOSOLE M 200 is a safe, effective, and trusted choice among healthcare professionals.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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