10mg Atorvastatin & 75mg Clopidogrel

Jun 12, 2023

Introduction

ATOVASTRIN CV 10 is a fixed-dose combination (FDC) therapy comprising two proven cardiovascular agents:Clopidogrel 75 mg – an antiplatelet drug that prevents clot formation and Atorvastatin 10 mg – a statin that reduces cholesterol and stabilizes atherosclerotic plaques.This combination is widely prescribed for patients at risk of heart attack, stroke, and other cardiovascular events, particularly after angioplasty, stent placement, or in chronic atherosclerotic conditions.

Composition

Each hard gelatin capsule of ATOVASTRIN CV 10 contains:

  • Atorvastatin Calcium IP eq. to Atorvastatin: 10 mg

  • Clopidogrel Bisulfate IP eq. to Clopidogrel: 75 mg

Key Indications & Uses

ATOVASTRIN CV 10 is primarily used for:

  • Secondary prevention of myocardial infarction (MI) and ischemic stroke

  • Patients with acute coronary syndrome (ACS) or stable coronary artery disease (CAD)

  • Post-angioplasty or coronary stent implantation

  • Managing dyslipidemia with co-existing high cardiovascular risk

  • Preventing peripheral arterial thrombosis

This dual therapy reduces the risk of future cardiovascular events by addressing both lipid management and platelet aggregation.

How ATOVASTRIN CV 10 Works

1. Atorvastatin (10 mg) – Statin / HMG-CoA Reductase Inhibitor

  • Lowers LDL cholesterol (bad cholesterol) and triglycerides

  • Increases HDL cholesterol (good cholesterol)

  • Stabilizes atherosclerotic plaques and improves endothelial function

  • Reduces vascular inflammation

2. Clopidogrel (75 mg) Antiplatelet / P2Y12 Inhibitor

  • Prevents platelets from aggregating, reducing thrombus (clot) formation

  • Irreversibly blocks the ADP receptor on platelets

  • Lowers risk of arterial clot-related events

Together, they provide comprehensive cardiovascular protection.

Dosage & Administration

  • Recommended Dose: One capsule of ATOVASTRIN CV 10 once daily or as directed by the physician.

  • Route: Oral

  • Timing: Preferably with or after meals to reduce gastrointestinal discomfort.

Dosing may be adjusted based on lipid profile, platelet function, and individual cardiovascular risk.

Side Effects

Common Side Effects:

  • Headache, dizziness

  • Indigestion, abdominal pain

  • Myalgia (muscle pain)

  • Mild increase in liver enzymes

Serious Side Effects:

  • Myopathy or Rhabdomyolysis (rare; associated with statins)

  • Bleeding or bruising (from Clopidogrel)

  • Allergic reactions

  • Liver dysfunction

  • Gastrointestinal bleeding

Immediate medical attention is needed if unexplained muscle pain, dark urine, or signs of bleeding occur.

Precautions and Warnings

  • Avoid in active liver disease

  • Monitor liver function tests periodically

  • Use cautiously in patients with:

    • Peptic ulcer disease

    • Recent trauma or surgery

    • Bleeding disorders

  • Avoid alcohol to minimize liver toxicity

  • Discontinue prior to elective surgery (consult doctor)

Drug Interactions

  • Increased bleeding risk with NSAIDs, aspirin, anticoagulants (e.g., warfarin)

  • CYP3A4 inhibitors (e.g., ketoconazole, erythromycin) may increase Atorvastatin levels

  • Proton Pump Inhibitors (PPIs) may reduce the effect of Clopidogrel

  • Cyclosporine and Fibrates may raise the risk of myopathy

Always consult your physician or pharmacist about potential interactions.

Storage Instructions

  • Store below 25°C in a cool, dry place.

  • Protect from direct light and moisture.

  • Keep out of reach of children.

FAQs About ATOVASTRIN CV 10

Q1. What is ATOVASTRIN CV 10 used for?

It is used to prevent heart attacks, strokes, and cardiovascular complications by reducing cholesterol and preventing blood clots.

Q2. Can I take ATOVASTRIN CV 10 after a stent procedure?

Yes. It is commonly prescribed post-angioplasty or stent placement to prevent thrombotic complications.

Q3. Should ATOVASTRIN CV 10 be taken on an empty stomach?

It is best taken after meals to reduce stomach upset.

Q4. Can ATOVASTRIN CV 10 be taken with aspirin?

Yes, but under medical supervision due to increased bleeding risk.

Q5. What tests are needed while taking this medicine?

Liver function tests, lipid profile, and platelet monitoring may be advised.

Conclusion

ATOVASTRIN CV 10 is a highly effective combination therapy designed to reduce the dual risk of cholesterol-related atherosclerosis and blood clot formation. With Atorvastatin 10 mg and Clopidogrel 75 mg, it offers a synergistic approach to cardiovascular disease management, especially in high-risk patients. As with all cardiovascular drugs, adherence, regular monitoring, and lifestyle modifications play a crucial role in long-term benefits.

About The Company

Steris Healthcare Pvt Ltd, widely recognized as Sterispharma, was established in February 2018 by a team of seasoned experts from the pharmaceutical sector. Based in Navi Mumbai, the company is proudly certified by WHO, GMP, and ISO, underscoring its unwavering commitment to quality and patient safety. Sterispharma is driven by a mission to make affordable, premium-quality medicines accessible throughout India, adhering strictly to WHO-recommended standards. Through its user-friendly online pharmacy platforms, customers can effortlessly order medications with home delivery services.

Sterispharma boasts an extensive portfolio of healthcare solutions, ranging from treatments for rare diseases to essential everyday healthcare needs. Their comprehensive product lineup addresses multiple therapeutic areas including Cardiology, Asthma, Respiratory Disorders, Nasal Care, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infective/Antibiotic Therapy, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. Medications are easily available for online purchase through their official websites — Sterisonline, Sterisindia, and Sterispharma — offering a seamless and reliable healthcare experience.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

BUY NOW

 

SHARE WITH