VALSARTONE 80H:Uses, Benefits, Dosage, Price & Side Effects...

May 11, 2024

VALSARTONE 80H is a scientifically formulated combination of Valsartan (80mg) and Hydrochlorothiazide – HCTZ (12.5mg), designed to offer effective and long-term management of high blood pressure (hypertension). Hypertension remains one of the most common lifestyle-related and genetic health concerns in India, and improper management can increase the risk of stroke, heart attack, heart failure, kidney disease, and other life-threatening complications.

VALSARTONE 80H belongs to the category of antihypertensive combination therapy, combining two powerful and complementary mechanisms:

  • Valsartan, an Angiotensin II Receptor Blocker (ARB), relaxes blood vessels to improve blood flow.

  • Hydrochlorothiazide, a thiazide diuretic, helps remove excess water and sodium from the body, reducing blood pressure more effectively.

For patients who need dual therapy to maintain optimal blood pressure levels, this medicine offers consistent and dependable control. Doctors commonly prescribe VALSARTONE 80H when a single medicine is not sufficient to manage hypertension or when patients require improved blood pressure stability.

This article explains the uses, benefits, dosage, side effects, precautions, and medical considerations associated with VALSARTONE 80H, ensuring that patients and caregivers understand the therapy in a clear and trustworthy manner.

Uses of VALSARTONE 80H

VALSARTONE 80H is primarily used for the treatment of:

1. Hypertension (High Blood Pressure)

Its main use is to lower elevated blood pressure. The combination works by reducing vascular resistance and removing excess fluid, helping maintain clinically safe pressure levels.

2. Reduction in Risk of Cardiovascular Complications

By controlling blood pressure, VALSARTONE 80H helps lower the risk of:

  • Heart attack

  • Stroke

  • Heart failure

  • Kidney failure

  • Arterial damage

This makes it especially beneficial for chronic hypertension patients.

3. Management of Resistant or Uncontrolled Hypertension

For patients who do not achieve adequate control with Valsartan alone, the addition of Hydrochlorothiazide significantly enhances blood pressure reduction.

4. Support in Kidney Protection (Long-Term)

Proper blood pressure control can help protect kidneys from damage, particularly in patients at risk for diabetic nephropathy or long-standing hypertension.

5. Management of Fluid Retention (Mild Cases)

Hydrochlorothiazide in the formulation reduces excess fluid accumulation, helping reduce:

  • Swelling

  • Edema

  • Water retention linked to blood pressure

6. Improvement of Overall Cardiac Function

By easing stress on the heart, this combination supports long-term cardiovascular health and reduces the workload on the cardiac muscles.

Benefits of VALSARTONE 80H

VALSARTONE 80H offers multiple clinical and patient-focused benefits due to the synergy between the ARB (Valsartan) and the diuretic component (HCTZ):

1. Dual Mechanism for Stronger Blood Pressure Control

The combination provides enhanced antihypertensive action compared to monotherapy.

  • Valsartan blocks angiotensin II, relaxing blood vessels.

  • HCTZ removes excess sodium and fluid.

Together, they provide consistent control throughout the day.

2. Reduced Risk of Heart-Related Emergencies

Consistently controlled blood pressure helps reduce the risk of:

  • Stroke

  • Heart attack

  • Sudden cardiac death

  • Heart failure

This makes Valsartan (80mg) and Hydrochlorothiazide – HCTZ (12.5mg), a preventive therapy for long-term heart wellness.

3. Gentle on Kidneys Compared to Other Antihypertensives

As an ARB-based combination, it is generally well-tolerated and kidney-friendly. It may be preferred over ACE inhibitors in patients who experience cough or intolerance.

4. Convenient Once-Daily Dosing

The long duration of action ensures blood pressure remains controlled for 24 hours, improving:

  • Compliance

  • Convenience

  • Treatment outcomes

5. Better Tolerance Compared to ACE Inhibitor Combinations

Patients who experience:

  • Dry cough

  • Angioedema

  • Throat irritation
    from ACE inhibitors (like ramipril or enalapril) often tolerate Valsartan-based combinations much better.

6. Helps Manage Fluid Retention

HCTZ’s diuretic action helps reduce:

  • Puffiness

  • Swelling

  • Water retention

This is helpful in overweight patients or those prone to fluid buildup.

7. Proven Results in the Indian Population

This combination is widely used in India for chronic hypertension management and is trusted for its stable, predictable results.

Dosage of VALSARTONE 80H

The dosage of  Valsartan (80mg) and Hydrochlorothiazide – HCTZ (12.5mg)should always be prescribed by a healthcare professional based on the patient’s blood pressure levels and medical profile.

Recommended Dosage

  • One tablet once daily, preferably at the same time every day.

  • It can be taken with or without food.

Important Dosage Guidelines

  • Do NOT exceed the recommended dose without consulting your doctor.

  • Take the medicine regularly, even if you feel normal.

  • High blood pressure usually has no symptoms — skipping doses can lead to silent complications.

  • If you miss a dose, take it as soon as you remember unless it’s close to the next dose.

  • Never double the dose.

Who Should Take It?

  • Patients with moderate to severe hypertension

  • Individuals not responding well to Valsartan alone

  • Patients requiring combination therapy for better control

Duration of Therapy

Hypertension is a chronic condition, so long-term use is typically required unless advised otherwise.

Side Effects of VALSARTONE 80H

VALSARTONE 80H is generally well-tolerated, but some patients may experience mild to moderate side effects. These may include:

Common Side Effects

  • Dizziness

  • Fatigue

  • Nausea

  • Headache

  • Low blood pressure (hypotension)

  • Muscle cramps

  • Dry mouth

  • Increased urination (due to HCTZ)

  • Stomach discomfort

Less Common Side Effects

  • Electrolyte imbalance (low sodium, potassium)

  • Skin rashes

  • Elevated blood sugar

  • Joint pain

  • Mild dehydration

Rare but Serious Side Effects

Seek immediate medical attention if you notice:

  • Severe dizziness or fainting

  • Irregular heartbeat

  • Shortness of breath

  • Swelling of face or throat

  • Severe dehydration

  • Sudden changes in kidney function

These reactions are rare but require urgent care.

Precautions and Warning

Before using VALSARTONE 80H, patients must take certain precautions to avoid complications.

1. Pregnancy and Breastfeeding

  • Not recommended during pregnancy, especially in the second and third trimester.

  • Avoid while breastfeeding unless specifically advised by a doctor.

2. Kidney and Liver Disorders

  • Patients with severe kidney disease should use caution.

  • Regular monitoring of electrolytes and kidney function may be needed.

3. Electrolyte Imbalances

HCTZ may reduce potassium, sodium, or magnesium levels.
Patients should undergo periodic blood tests if they are at risk.

4. Dehydration

Avoid excessive sweating, alcohol, or heavy exercise without proper hydration, as this may cause:

  • Low blood pressure

  • Severe dizziness

  • Muscle cramps

5. Patients with Diabetes

HCTZ may slightly increase blood sugar levels.
Diabetic patients require monitoring or dose adjustments.

6. Avoid Alcohol Consumption

Alcohol can enhance the blood-pressure-lowering effect, leading to dizziness or fainting.

7. Drug Interactions

Inform your doctor if you are taking:

  • Lithium

  • NSAIDs

  • Other BP medicines

  • Diuretics

  • Steroids

  • Antidiabetic medications

Drug interactions may require dose adjustments or close monitoring.

8. Not for Sudden Blood Pressure Emergencies

This medicine is meant for long-term control, not immediate relief.

Conclusion

VALSARTONE 80H is an effective, well-researched, and widely trusted combination therapy for long-term management of high blood pressure. With Valsartan providing vascular relaxation and Hydrochlorothiazide reducing excess fluid, the medicine offers strong and consistent control over hypertension. It reduces the risks of stroke, heart attack, and kidney failure while supporting long-term cardiovascular health.

FAQs (Frequently Asked Questions)

1. What is VALSARTONE 80H used for?

It is used to manage high blood pressure and prevent heart-related complications.

2. Is it safe for long-term use?

Yes, it is commonly prescribed for long-term hypertension management under medical supervision.

3. Can I take it with food?

Yes, it can be taken with or without food.

4. Does it cause frequent urination?

Yes, due to the diuretic (HCTZ), you may experience increased urination.

5. Can diabetic patients take it?

Yes, but blood sugar levels should be monitored.

6. Is it safe during pregnancy?

No, it should not be used during pregnancy.

7. How long does it take to show results?

Blood pressure reduction begins within a few hours, with full effect achieved in 2–4 weeks.

8. Can I stop taking it if my BP becomes normal?

No, stopping suddenly may increase blood pressure again. Consult your doctor.

9. What should I avoid while taking this medicine?

Avoid alcohol, dehydration, and other medications unless approved by your doctor.

10. Is VALSARTONE 80H better than single-drug therapy?

Yes, for patients who need additional control, this dual therapy is more effective than Valsartan alone.

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