Ticagrelor 90mg- Uses, Benefits, Dosage,& Side Effects
May 03, 2024
Introduction to Ticagrelor 90 mg Uses and TICAGRACE 90
If you are seeking detailed information about ticagrelor 90 mg uses, you are in the right place. Ticagrelor, marketed as TICAGRACE 90, is a widely prescribed medication that plays a vital role in preventing serious heart-related complications. This article provides an in-depth overview, including chemical composition, mechanism of action, indications, dosage, safety, side effects, and much more—all explained in a patient-friendly manner.
Ticagrelor 90 mg is an oral antiplatelet drug primarily used in the prevention of blood clots that can lead to heart attacks, strokes, or death in patients with acute coronary syndrome (ACS) or a history of myocardial infarction (MI). Sold under the brand name TICAGRACE 90 by Steris Healthcare Pvt Ltd, this medication ensures better cardiovascular outcomes by inhibiting platelet aggregation.
The tab ticagrelor 90 mg uses extend to reducing the risk of cardiovascular events and improving blood flow, which is crucial for patients recovering from heart conditions or at high risk of developing them.
Chemical Composition and Formulations of Ticagrelor 90 mg
Ticagrelor is chemically classified as a cyclopentyltriazolopyrimidine, with the molecular formula C₂₃H₂₈F₂N₆O₄S. It belongs to the class of drugs called platelet aggregation inhibitors.
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Active Ingredient: Ticagrelor 90 mg per tablet
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Other Ingredients: Inactive components include excipients that aid in tablet stability and absorption.
The formulation is available as oral tablets of 90 mg, designed for easy administration with consistent bioavailability.
Mechanism of Action of Ticagrelor 90 mg
Ticagrelor works by selectively and reversibly inhibiting the P2Y12 receptor on platelets. This receptor plays a key role in platelet activation and aggregation—a process crucial for clot formation.
Unlike other antiplatelet agents such as clopidogrel, ticagrelor provides rapid and potent platelet inhibition due to its direct action and reversible binding. This helps prevent arterial clots that cause heart attacks and strokes.
Uses and Indications of Ticagrelor 90 mg: Why TICAGRACE 90 is Prescribed
The primary ticagrelor 90 mg uses include:
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Prevention of thrombotic cardiovascular events in patients with acute coronary syndrome (ACS), including unstable angina and non-ST-elevation myocardial infarction (NSTEMI).
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Secondary prevention of MI in patients with a history of heart attack to minimize the risk of recurrent events.
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Reducing the risk of stroke and cardiovascular death in patients with a history of myocardial infarction.
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Used alongside aspirin as dual antiplatelet therapy in post-PCI (percutaneous coronary intervention) patients.
Dosage and Administration Guidance for TICAGRACE 90
It is essential to follow your healthcare provider’s instructions carefully when taking tab ticagrelor 90 mg. The typical dosing is as follows:
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Loading Dose: Usually, a single 180 mg dose (2 tablets of 90 mg) is administered initially, especially in acute settings.
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Maintenance Dose: 90 mg twice daily, with or without food.
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Ticagrelor should be taken regularly without missing doses.
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Avoid stopping ticagrelor abruptly without consulting a doctor, as this may increase the risk of heart complications.
Efficacy and Clinical Evidence Supporting Ticagrelor 90 mg Uses
Clinical trials like the PLATO study have demonstrated the superior efficacy of ticagrelor over clopidogrel in reducing cardiovascular death, MI, and stroke in ACS patients. TICAGRACE 90 formulations are backed by solid evidence showing improved survival rates and reduced rates of thrombotic events in high-risk patients.
Side Effects and Safety Profile of Ticagrelor 90 mg
While TICAGRACE 90 is effective, patients should be aware of possible side effects:
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Common Side Effects:
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Shortness of breath (dyspnea)
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Headache
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Dizziness
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Nausea
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Minor bleeding (nosebleeds, gum bleeding)
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Serious Side Effects:
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Major bleeding events
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Allergic reactions (rashes, swelling)
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Bradyarrhythmia (slow heartbeat)
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If you notice severe bleeding, allergic symptoms, or persistent chest pain, seek medical attention immediately.
Contraindications and Precautions with Ticagrelor 90 mg
Ticagrelor is contraindicated in patients:
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With active pathological bleeding (e.g., peptic ulcers, intracranial hemorrhage).
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Who have severe liver impairment.
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Known hypersensitivity to ticagrelor or any component of the formulation.
Use with caution if you have:
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Bleeding disorders
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History of transient ischemic attack or stroke
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Patients scheduled for surgery
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Pregnant or breastfeeding women (consult your doctor)
Drug Interactions: What to Avoid While Using Ticagrelor 90 mg
Several drugs can interact with TICAGRACE 90 and affect its efficacy or safety:
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Avoid combining with: Strong CYP3A inhibitors (e.g., ketoconazole), which can increase ticagrelor levels.
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Avoid co-administration with: CYP3A inducers (e.g., rifampin), which can reduce its effectiveness.
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Be cautious with: Other blood thinners (warfarin, NSAIDs), aspirin doses above 100 mg daily, and medications causing bleeding risk.
Always disclose your full medication list to your healthcare provider.
Warnings and Regulatory Status of Ticagrelor 90 mg
Regulatory authorities recommend cautious use of ticagrelor due to bleeding risks. Warnings include:
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Increased risk of bleeding complications.
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Not recommended for patients with severe bleeding risks.
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Close monitoring required during combined antiplatelet therapy.
TICAGRACE 90 is approved by major health regulatory bodies, including the Drugs Controller General of India (DCGI), and adheres to global safety standards.
Patient Advice and Tips for Effective Use of Ticagrelor 90 mg
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Take tablets at the same time every day.
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Do not crush or chew the tablets.
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Inform your doctor of any unusual bruising or bleeding.
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Avoid alcohol and inform your doctor about other medications you take.
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Carry medical identification indicating you are on antiplatelet therapy.
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Do not discontinue without consulting your healthcare provider.
Cost and Availability of TICAGRACE 90
TICAGRACE 90 by Steris Healthcare Pvt Ltd is competitively priced, making effective cardiovascular care accessible. Available at major pharmacies and authorized medical outlets, you can obtain this medication with a valid prescription.
Frequently Asked Questions (FAQs) on Ticagrelor 90 mg
Q1: What is ticagrelor 90 mg used for?
A1: It is used to prevent blood clots in patients with acute coronary syndrome and those at risk of heart attack or stroke.
Q2: Can I take ticagrelor with aspirin?
A2: Yes, ticagrelor is often prescribed with low-dose aspirin as dual antiplatelet therapy.
Q3: What should I do if I miss a dose?
A3: Take it as soon as you remember, but do not double the next dose. Contact your doctor if unsure.
Q4: Are there dietary restrictions while taking ticagrelor?
A4: No strict restrictions, but avoid alcohol and inform your doctor about any supplements or herbal products.
Q5: Is ticagrelor safe during pregnancy?
A5: Safety during pregnancy is not well established; consult your doctor if you are pregnant or planning pregnancy.
Conclusion: Why Choose TICAGRACE 90 from Steris Healthcare Pvt Ltd for Ticagrelor 90 mg
Choosing the right medication is crucial for managing heart conditions. TICAGRACE 90 offers reliable and scientifically validated effectiveness for ticagrelor 90 mg. Manufactured by Steris Healthcare Pvt Ltd, this brand stands out due to:
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Quality manufacturing standards
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Regulatory compliance
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Competitive pricing and accessibility
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Strong customer and healthcare provider trust
If you or your loved one requires antiplatelet therapy, consulting a healthcare provider about TICAGRACE 90 ensures you receive a safe and effective product tailored to your health needs.
Call to Action
For trusted cardiovascular protection with ticagrelor 90 mg, ask your doctor or pharmacist about TICAGRACE 90 by Steris Healthcare Pvt Ltd today. Take proactive steps towards a healthier heart with a medication designed for your safety and wellbeing!
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