SULTAMYLIN 375 & Sultamicillin (375mg): Key Benefits , Uses , Dosages and other Information.

Introduction

SULTAMYLIN 375 is an advanced oral antibiotic formulation containing Sultamicillin 375 mg, a mutual prodrug of Ampicillin and Sulbactam. This combination offers dual action—Ampicillin acts as a broad-spectrum penicillin-class antibiotic, while Sulbactam functions as a beta-lactamase inhibitor, protecting Ampicillin from enzymatic degradation.Sultamicillin tablets 375 mg are prescribed to treat a wide range of bacterial infections, particularly those caused by beta-lactamase-producing organisms that are resistant to Ampicillin alone.

Composition and Mechanism of Action

Active Ingredient:

• Sultamicillin 375 mg

  • A mutual prodrug that breaks down into two active components in the body:

    • Ampicillin: Inhibits bacterial cell wall synthesis.

    • Sulbactam: Inhibits beta-lactamase enzymes, which bacteria produce to resist beta-lactam antibiotics.

This combination enhances antibacterial activity against resistant strains and extends the spectrum of activity, making Sultamicillin tablets 375 mg highly effective.

Indications and Uses of Sultamicillin Tablets 375 mg

SULTAMYLIN 375 is indicated for the treatment of infections caused by susceptible strains of bacteria, including:

• Upper and lower respiratory tract infections

• Urinary tract infections (UTIs)

• Skin and soft tissue infections

• Gynecological infections

• Intra-abdominal infections

• Ear, nose, and throat (ENT) infections

These uses make tab Sultamicillin 375 a preferred oral antibiotic when a broader antimicrobial spectrum is needed.

Sultamicillin Tablet Uses Summary

The sultamicillin tablet uses are guided by the nature and severity of the infection and the patient’s response to therapy.

Dosage and Administration

• Adults: The usual dose is 375 mg twice daily for mild to moderate infections.

• Duration: Typically 5–14 days, depending on the infection type.

• Administration: Should be taken with or without food, but ideally after meals to reduce gastrointestinal discomfort.

• Renal Impairment: Dose adjustment may be needed.

Always follow your doctor’s dosage instructions. Self-medication or misuse may lead to antibiotic resistance.

Benefits of SULTAMYLIN 375

• Dual-action antibiotic with extended spectrum

• Effective against beta-lactamase-producing bacteria

• Convenient oral tablet form for outpatient therapy

• Reduced risk of resistance compared to Ampicillin monotherapy

• Suitable alternative to intravenous antibiotics in mild to moderate infections

These benefits make tab Sultamicillin a reliable treatment option for clinicians.

Side Effects

Most patients tolerate Sultamicillin 375 mg well. However, some may experience:

Common Side Effects

• Diarrhea

• Nausea or vomiting

• Abdominal discomfort

• Skin rash or itching

Serious Side Effects (Rare)

• Allergic reactions (hives, difficulty breathing)

• Pseudomembranous colitis

• Hepatic dysfunction (rare liver enzyme elevation)

• Blood dyscrasias

Report any unusual or persistent symptoms to your healthcare provider promptly.

Precautions and Warnings

• Avoid use if allergic to penicillin or beta-lactam antibiotics.

• Use with caution in renal impairment, with dose adjustment.

• Monitor for signs of superinfection or resistant organisms during prolonged use.

• Pregnant and breastfeeding women should only use under medical advice.

• Prolonged use may result in fungal or bacterial overgrowth.

Drug Interactions

Sultamicillin may interact with:

• Allopurinol: Increases risk of rash

• Oral contraceptives: May reduce contraceptive efficacy

• Probenecid: Delays renal excretion of Sultamicillin

• Anticoagulants (e.g., warfarin): May alter INR levels

Inform your doctor about all medications you are currently using.

Storage Instructions

• Store below 25°C in a dry place.

• Protect from light and moisture.

• Keep out of reach of children.

Frequently Asked Questions (FAQ) – SULTAMYLIN 375

1. What is Sultamicillin 375 mg used for?

Sultamicillin 375 mg is used to treat bacterial infections such as respiratory tract infections, urinary tract infections, skin and soft tissue infections, ENT infections, and gynecological infections caused by susceptible bacteria.

2. How does SULTAMYLIN 375 work?

SULTAMYLIN 375 contains Sultamicillin, which is a combination of Ampicillin (a penicillin antibiotic) and Sulbactam (a beta-lactamase inhibitor). This combination works by killing bacteria and preventing bacterial resistance.

3. Is SULTAMYLIN 375 effective against antibiotic-resistant bacteria?

Yes, Sultamicillin is effective against certain beta-lactamase-producing bacteria that are resistant to Ampicillin alone, thanks to the presence of Sulbactam.

4. What is the usual dosage of Sultamicillin tablets 375 mg?

The typical adult dosage is 375 mg twice daily, or as directed by your physician based on the severity of the infection.

5. Can I take SULTAMYLIN 375 on an empty stomach?

Yes, SULTAMYLIN 375 can be taken with or without food, though taking it after meals may reduce stomach upset.

6. Are there any side effects of Sultamicillin 375 mg?

Common side effects include:

• Nausea

• Diarrhea

• Abdominal discomfort

• Skin rash

Serious but rare side effects may include allergic reactions, liver enzyme changes, or superinfections.

7. Is Sultamicillin 375 safe during pregnancy or breastfeeding?

Use during pregnancy or breastfeeding should only be under medical supervision. Your doctor will weigh the potential benefits and risks before prescribing it.

Conclusion

SULTAMYLIN 375, containing Sultamicillin tablets 375 mg, offers a potent oral antibiotic solution against a wide spectrum of bacterial infections. By combining the effects of Ampicillin and Sulbactam, this formulation ensures high efficacy even in resistant bacterial strains. Whether it is a respiratory, urinary, or soft tissue infection, Sultamicillin 375 provides trusted relief with excellent tolerability.Healthcare professionals trust Sultamicillin 375 mg for its broad-spectrum coverage, oral convenience, and reduced resistance risk, making it an essential addition to modern antibiotic therapy.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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