Sodium Picosulphate (10mg) & PICOSOLAX 10 : Uses, Side Effects,Benifite, Dosage and Call to Action.

May 23, 2024

Introduction

Sodium Picosulfate is a stimulant laxative used for the treatment of constipation and for bowel cleansing before diagnostic procedures such as colonoscopy. It works by stimulating the nerves in the colon to increase peristalsis, thereby promoting bowel movements.

Composition of PICOSOLAX 10

Each PICOSOLAX 10 tablet contains:

  • Sodium Picosulfate IP – 10 mg

  • Excipients – q.s.

  • Dosage Form: Film-coated tablet

  • Packaging: Blister/strip of 10 tablets

Sodium Picosulfate 10 mg Uses

PICOSOLAX 10 is used for:

  • Treatment of occasional or chronic constipation

  • Evacuation of bowels before radiological or endoscopic procedures (e.g., colonoscopy, barium enema)

  • Adjunct in preoperative bowel preparation

It offers a gentle yet effective relief, generally within 6–12 hours of intake.

How Sodium Picosulfate Works

Sodium Picosulfate is a prodrug, which becomes active in the colon when it is hydrolyzed by gut bacteria. The active form stimulates colonic nerves, resulting in:

  • Enhanced intestinal motility

  • Increased peristalsis

  • Faster movement of stools

  • Water retention in the colon to soften stools

Key Benefits of PICOSOLAX 10

  • Fast-acting relief from constipation

  • Gentle on the stomach and colon

  • Minimal absorption systemically (acts locally)

  • Well tolerated across age groups

  • Suitable for bowel preparation in diagnostic settings

Dosage and Administration

For Constipation:

  • Adults: 5–10 mg once daily, preferably at bedtime

  • Children >4 years: 2.5–5 mg, as per physician’s advice

For Bowel Preparation:

  • As advised by a physician, often combined with clear fluids and electrolyte solutions.

Note: Always take with water. Do not chew or crush the tablet.

Side Effects of Sodium Picosulfate

Common Side Effects:

Rare but Serious Effects:

  • Electrolyte imbalance (especially with overuse)

  • Dehydration

  • Hypokalemia

 Avoid prolonged use without medical supervision to prevent dependency or chronic bowel dysfunction.

Warnings and Precautions

  • Do not use in case of intestinal obstruction, appendicitis, or acute surgical abdomen

  • Avoid in patients with severe dehydration or electrolyte imbalance

  • Not recommended for children <4 years without doctor’s advice

  • Pregnant and breastfeeding women should use only if clearly needed

Drug Interactions

Be cautious when using with:

  • Diuretics or corticosteroids – risk of electrolyte imbalance

  • Cardiac glycosides (e.g., Digoxin) – effectiveness may be altered

  • Other laxatives – additive effects and increased risk of side effects

Storage and Handling

  • Store at room temperature (below 25°C)

  • Protect from moisture and direct sunlight

  • Keep out of reach of children

  • Do not use beyond expiry date

Frequently Asked Questions (FAQs)

1. What is PICOSOLAX 10 used for?

PICOSOLAX 10 is used to relieve constipation and to clean the bowel before medical examinations like colonoscopy.

2. How long does Sodium Picosulfate take to work?

It usually works within 6 to 12 hours after oral administration.

3. Can Sodium Picosulfate be used daily?

It is not recommended for daily long-term use. Overuse can cause dependence and electrolyte imbalances.

4. Is PICOSOLAX 10 safe in pregnancy?

Use in pregnancy only under medical supervision. It is generally avoided in early pregnancy due to uterine stimulation concerns.

5. Can I take PICOSOLAX 10 with food?

Yes, it can be taken with or without food. However, bedtime dosing is preferred for morning bowel movement.

Conclusion

PICOSOLAX 10 offers effective, predictable relief from constipation and is a preferred choice for bowel preparation before medical procedures. Its well-established safety and mechanism of action make it a dependable solution in both clinical and general care settings. Manufactured under WHO-GMP standards, PICOSOLAX 10 from Steris Healthcare ensures purity, potency, and consistent efficacy.

About The Company

Steris Healthcare Pvt Ltd, widely recognized as Sterispharma, was established in February 2018 by a team of seasoned experts from the pharmaceutical sector. Based in Navi Mumbai, the company is proudly certified by WHO, GMP, and ISO, underscoring its unwavering commitment to quality and patient safety. Sterispharma is driven by a mission to make affordable, premium-quality medicines accessible throughout India, adhering strictly to WHO-recommended standards. Through its user-friendly online pharmacy platforms, customers can effortlessly order medications with home delivery services.

Sterispharma boasts an extensive portfolio of healthcare solutions, ranging from treatments for rare diseases to essential everyday healthcare needs. Their comprehensive product lineup addresses multiple therapeutic areas including Cardiology, Asthma, Respiratory Disorders, Nasal Care, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infective/Antibiotic Therapy, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. Medications are easily available for online purchase through their official websites — Sterisonline, Sterisindia, and Sterispharma — offering a seamless and reliable healthcare experience.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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