Sitagliptin and Metformin SR (1000 mg)

sitagliptin and metformin

When managing Type 2 Diabetes, choosing the right medication is crucial. ST-GLIPTIN M50/1000 offers a powerful combination of sitagliptin and metformin, two antidiabetic agents that work together to control blood sugar more effectively. This dual-drug therapy helps patients gain better glycemic control while minimizing side effects and improving overall quality of life.

As a patient, understanding how sitagliptin and metformin function together can empower you to make better health decisions. Whether you’re newly diagnosed or seeking better sugar level stability, this article covers everything from uses and benefits to why Steris Healthcare is a trusted name in diabetes care.

What is ST-GLIPTIN M50/1000?

ST-GLIPTIN M50/1000 is a fixed-dose combination medication that contains:

• Sitagliptin Phosphate 50 mg

• Metformin Hydrochloride 1000 mg (Extended-Release)

This combination is specifically formulated to treat Type 2 Diabetes Mellitus (T2DM), where lifestyle modifications alone are insufficient to maintain blood glucose levels. It is often prescribed when monotherapy (either sitagliptin or metformin alone) fails to provide adequate glycemic control.

sitagliptin and metformin hydrochloride tablets uses

Understanding the therapeutic effects of sitagliptin and metformin hydrochloride tablets helps patients use the medication responsibly and confidently. Here are the primary uses:

• Helps Lower HbA1c: When used along with diet and exercise, this combination effectively lowers HbA1c levels over time.

• Controls Fasting and Post-Meal Sugar Levels: Metformin works on liver glucose production, while sitagliptin enhances the body’s insulin response after meals.

• Weight Neutral or Supportive: Unlike sulfonylureas or insulin, this combination typically doesn’t cause weight gain.

• Reduces the Risk of Hypoglycemia: Sitagliptin and metformin tablets do not significantly drop blood sugar suddenly, making them safer for daily use.

This medication may also be combined with other antidiabetic agents like sulfonylureas or insulin under your doctor’s supervision.

How Do Sitagliptin and Metformin Work Together?

• Metformin decreases glucose production in the liver and increases insulin sensitivity.

• Sitagliptin is a DPP-4 inhibitor that increases incretin levels, enhancing insulin release after meals and decreasing glucagon secretion.

Together, they complement each other by targeting multiple pathways to control high blood sugar levels throughout the day.

Dosage and Administration

• Typically, ST-GLIPTIN M50/1000 is taken once daily with food to minimize gastrointestinal side effects.

• The dosage should be adjusted based on patient tolerance, kidney function, and blood sugar levels.

• Patients should never split, crush, or chew extended-release tablets.

Always consult your doctor before changing your dose or starting any new medication.

Common Side Effects

While most patients tolerate sitagliptin and metformin hydrochloride tablets well, some may experience mild side effects, especially in the first few weeks:

• Nausea

• Diarrhea

• Headache

• Upper respiratory tract infections

• Flatulence

• Abdominal discomfort

Severe but rare side effects like lactic acidosis (in metformin) or pancreatitis (in sitagliptin) require immediate medical attention.

Precautions to Take

• Kidney function should be assessed before starting and periodically during treatment.

• Avoid alcohol, as it increases the risk of lactic acidosis.

• Not suitable for Type 1 diabetes or diabetic ketoacidosis.

• Inform your doctor if you’re scheduled for surgery or radiological procedures with contrast dyes.

Why ST-GLIPTIN M50/1000 by Steris Healthcare is a Better Choice

In the vast landscape of diabetes medications, Steris Healthcare stands out for several reasons:

1. WHO-GMP Certified Manufacturing: Quality that meets international healthcare standards.

2. Precision Formulation: Each tablet delivers accurate dosage for predictable outcomes.

3. Patient-Centric Design: Extended-release metformin ensures gentler absorption and fewer GI issues.

4. Affordable for All: High-quality medication without the high price tag.

5. Pan-India Availability: Accessible in major cities and remote regions through an extensive distribution network.

6. Backed by Clinical Expertise: Steris invests in R&D to ensure effectiveness, stability, and safety.

When patients choose ST-GLIPTIN M50/1000, they don’t just choose a tablet — they choose reliability, science, and support.

Frequently Asked Questions (FAQs)

Q1. What is ST-GLIPTIN M50/1000 used for?
A: It is used to manage blood sugar levels in patients with Type 2 Diabetes.

Q2. How long does it take to see results?
A: Most patients start seeing improvements in fasting and post-meal sugar within 1–2 weeks.

Q3. Can I take it along with insulin or other antidiabetic drugs?
A: Yes, under your doctor’s supervision, it can be used as part of combination therapy.

Q4. Are there any diet restrictions?
A: Patients are advised to follow a low-carb, high-fiber diabetic diet and avoid alcohol.

Q5. Is ST-GLIPTIN M50/1000 safe for long-term use?
A: Yes, it is generally safe for long-term use when monitored regularly by your physician.

Conclusion

For patients managing Type 2 Diabetes, ST-GLIPTIN M50/1000 is a proven, powerful, and well-tolerated treatment choice. With the dual action of sitagliptin and metformin, it offers better control over blood sugar, fewer side effects, and improved quality of life. Manufactured by Steris Healthcare, a name trusted for excellence and quality in the pharmaceutical space, this combination tablet provides more than just glucose regulation — it gives confidence and stability to live life fully.

So, if you're looking for a reliable treatment plan for diabetes, consider the benefits of sitagliptin and metformin, and ask your healthcare provider about ST-GLIPTIN M50/1000 today.