Prilocaine (2.5%), Lidocaine (2.5%) Gel

Introduction

PRILIBIDO PLUS is a premium topical anesthetic gel formulated with Lidocaine and Prilocaine, two potent local anesthetics widely recognized for their ability to numb the skin and mucous membranes effectively. Produced under the highest standards by Steris Healthcare Pvt Ltd, this gel is designed to ensure safe, rapid, and targeted pain relief in a variety of clinical and cosmetic settings. It is a topical anesthetic used to numb the skin before certain procedures. Whether it’s for minor surgical procedures, dermal interventions, or relieving surface pain, PRILIBIDO PLUS stands out as a trusted solution.

In this guide, we’ll explore everything you need to know—from chemical formulation to usage, efficacy, safety, and availability—to help both patients and healthcare professionals understand the full potential of Lidocaine and Prilocaine gel.

Chemical Composition and Formulations

PRILIBIDO PLUS contains a balanced combination of:

• Lidocaine 2.5% w/w

• Prilocaine 2.5% w/w

• Water-based gel base for quick absorption and skin compatibility.

This eutectic mixture allows both active agents to remain in a liquefied state at room temperature, enhancing penetration into the skin and offering a faster onset of action.

Formulation Type:
Topical anesthetic gel for external use only.
Packaging:
Available in sterile tubes or single-use sachets.

The synergistic action of lidocaine and prilocaine provides deeper numbing than when used individually, which is especially beneficial in dermatological and minor surgical practices.

Mechanism of Action

Lidocaine and Prilocaine belong to the amide group of local anesthetics. They work by blocking sodium channels in nerve endings, preventing the generation and transmission of pain signals to the brain.

Once applied to the skin, the gel penetrates the epidermis and dermis layers. The nerves become temporarily non-functional, resulting in local anesthesia that prevents pain during procedures or relieves existing discomfort.

Key Features of Action:

• Fast onset: Numbing begins within 20–30 minutes.

• Depth of anesthesia: Up to 5 mm after 60 minutes of application.

• Duration: Effects can last up to 2 hours post-application.

Uses and Indications

PRILIBIDO PLUS is indicated in various medical, cosmetic, and therapeutic scenarios. Here are its top uses:

1. Dermatological Procedures

• Laser hair removal

• Tattooing or tattoo removal

• Microneedling and chemical peels

• Skin biopsies and mole removals

2. Cosmetic Interventions

• Dermal filler or Botox injections

• Lip augmentations

• Thread lifts

3. Minor Surgical Applications

• Suturing of minor wounds

• Skin graft procedures

• IV insertions or cannulation

• Vaccination and blood draws in children

4. Pain Management

• Hemorrhoid discomfort

• Minor burns or abrasions

• Insect bites or sunburns

5. Sexual Health (Under Supervision)

• Occasionally used in premature ejaculation treatments (off-label use)

Its versatility across fields makes PRILIBIDO PLUS a valuable asset for doctors, aestheticians, and patients alike.

Dosage and Administration

Correct administration is critical for safe and effective use of PRILIBIDO PLUS.

General Guidelines:

Step-by-Step Instructions:

1. Clean the targeted area with mild soap or antiseptic.

2. Apply a thick layer of PRILIBIDO PLUS (do not rub).

3. Cover with an occlusive dressing (optional for deeper numbing).

4. Wait the recommended time.

5. Remove excess gel before the procedure.

 Avoid broken skin unless directed by a healthcare provider. Do not exceed 10g in a single application unless under strict medical supervision.

Efficacy and Clinical Evidence

Numerous studies support the efficacy of Lidocaine and Prilocaine Gel:

• Clinical trials have shown a 90% reduction in pain perception for procedures like needle insertions and laser treatments.

• Comparative studies found PRILIBIDO PLUS’s active combination more effective than lidocaine-only or prilocaine-only gels.

• Patient feedback frequently highlights comfort during sensitive procedures and improved recovery.

Its efficacy, combined with low systemic absorption, makes it ideal for outpatient and cosmetic use without sedation or injectable anesthesia.

Side Effects and Safety Profile

While generally well-tolerated, users should be aware of possible side effects:

Common (mild & temporary):

• Redness

• Swelling

• Mild burning or itching

• Temporary numbness beyond application area

Rare but Serious:

• Allergic reactions (rash, swelling of face/tongue)

• Methemoglobinemia (especially in infants)

• Irregular heartbeat or dizziness (overuse)

Safety Precautions:

• Always do a patch test for first-time users.

• Avoid application on infected, inflamed, or broken skin.

• Do not use near eyes or inside mouth/nose unless prescribed.

Consult a physician immediately if unusual symptoms occur.

Contraindications and Precautions

Contraindications:

• Known hypersensitivity to amide-type anesthetics

• Infants under 3 months

• Patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency (risk of methemoglobinemia)

Precautions:

• Use cautiously in people with liver or heart conditions

• Avoid long-term or large-surface use unless prescribed

• Pregnant or breastfeeding women should consult a physician before use

Drug Interactions

Though topical application reduces the risk of systemic interactions, caution is advised when using the following:

• Antiarrhythmic drugs (e.g., amiodarone, mexiletine)

• Other local anesthetics or numbing agents

• Nitrates or nitrites (increased risk of methemoglobinemia)

• Sulfonamides and certain antibiotics

Always disclose all medications to your healthcare provider before using PRILIBIDO PLUS.

Warnings and Regulatory Status

Warnings:

• For external use only

• Avoid prolonged use

• Do not use on mucosal surfaces unless directed

• Keep out of reach of children

Regulatory Status in India:

• PRILIBIDO PLUS is an OTC-approved formulation in many regions but should be used under the guidance of a professional for surgical or high-dose use.

• Manufactured under GMP and ISO-certified facilities as per DCGI guidelines.

Steris Healthcare Pvt Ltd ensures strict quality control, purity, and efficacy in every batch.

Patient Advice and Tips

• Patch testing is key: Try a small quantity 24 hours before full use.

• Stick to dosage instructions: Overuse can lead to systemic toxicity.

• Monitor children closely if using in pediatric cases.

• Use on intact skin only.

• If you're undergoing a procedure, inform your provider you're using a numbing gel.

• After use, wash hands thoroughly and avoid touching eyes.

For maximum effectiveness, always follow directions and timing recommendations precisely.

Why Choose Steris Healthcare Pvt Ltd?

When it comes to safe, effective, and affordable topical anesthesia, Steris Healthcare Pvt Ltd has earned trust across India for the following reasons:

 Quality Assurance

Every batch of PRILIBIDO PLUS undergoes rigorous quality checks as per international pharmaceutical standards.

 Research-Driven Innovation

Formulations are backed by clinical data and R&D insights, ensuring effectiveness and patient comfort.

 Wide Distribution Network

Available across India in both offline and online channels, with excellent supply-chain reliability.

 Customer-Centric Policies

Steris offers transparent labeling, multilingual patient instructions, and 24/7 customer support.

 Ethical Manufacturing

The company operates with WHO-GMP, ISO, and DCGI certifications to ensure ethical, compliant, and safe production.

Conclusion

PRILIBIDO PLUS by Steris Healthcare Pvt Ltd is more than just a numbing gel—it’s a patient-first solution trusted by dermatologists, cosmetic specialists, and general practitioners alike. Whether you're planning a cosmetic enhancement, a minor surgery, or pain-relieving intervention, this lidocaine and prilocaine combination offers rapid, deep, and reliable anesthesia with minimal risk.

Its accessible pricing, superior quality, and flexible use in both clinical and at-home environments make it a standout product in the Indian healthcare and beauty market.

If you're looking for an effective, patient-friendly, and trustworthy topical anesthetic, PRILIBIDO PLUS is the name to remember.