N-Acetylecystine film coated 300 mg + Pyridoxamine 75 mg

Introduction

STYLECYSTIN FORTE is a specialized formulation combining N-Acetylcysteine (NAC) and Pyridoxamine Dihydrochloride, designed to combat oxidative stress, inflammation, and kidney-related complications in patients with chronic diseases such as diabetes, hypertension, and chronic kidney disease (CKD). This dual-action therapy offers renal protection, mitigates progression of nephropathy, and contributes to cellular detoxification.

What is N-Acetylcysteine (NAC)?

NAC is a powerful antioxidant and precursor to glutathione, one of the body’s key natural detoxifiers. It is used to:

• Break down mucus in lung conditions

• Protect kidneys from contrast-induced nephropathy

• Reduce oxidative damage in liver, kidneys, and neurons

What is Pyridoxamine Dihydrochloride?

Pyridoxamine is a vitamin B6 derivative known for its anti-glycation and anti-inflammatory properties. It:

• Prevents formation of advanced glycation end-products (AGEs)

• Protects renal and vascular structures

• Helps prevent diabetic nephropathy

• Supports mitochondrial health

Uses of STYLECYSTIN FORTE

This combination is commonly prescribed for:

✅ Diabetic nephropathy (kidney damage in diabetes)
✅ Chronic kidney disease (CKD)
✅ Contrast-induced nephropathy (CIN)
✅ Glomerular and tubular inflammation
✅ Oxidative stress management
✅ Hyperglycemia-induced oxidative injury
✅ Cystic fibrosis and liver detox support (NAC’s role)
✅ Prevention of cardiovascular complications due to AGEs

Mechanism of Action

1. N-Acetylcysteine (NAC) replenishes intracellular glutathione, a critical antioxidant, and directly neutralizes free radicals, reducing oxidative damage to kidneys and vasculature.

2. Pyridoxamine Dihydrochloride inhibits non-enzymatic glycation, blocking the formation of AGEs, which contribute to renal fibrosis and endothelial dysfunction.

Together, they slow CKD progression, protect nephrons, and improve overall renal and vascular health.

Dosage & Administration

Typical Dosage:

• One tablet of STYLECYSTIN FORTE once or twice daily, or as prescribed by the physician

Administration Tips:

• Take after meals with water

• Do not crush or chew the tablet

• Always follow your healthcare provider's instructions

Key Benefits of STYLECYSTIN FORTE