Mesalamine (800mg) '''

Introduction

MESALMILE 800 ER is an extended-release tablet containing Mesalamine 800 mg, specially designed to treat and manage ulcerative colitis, proctitis, and Crohn’s colitis. Formulated by Steris Healthcare, this delayed-release version ensures that the medication is delivered precisely where it is needed – in the colon – to control inflammation and maintain long-term remission in patients with inflammatory bowel disease (IBD).

Composition

• Each enteric-coated delayed-release tablet contains:

  • Mesalamine IP (as extended-release formulation) – 800 mg

What is Mesalamine 800 mg?

Mesalamine (also known as mesalazine or 5-ASA) is a gut-specific anti-inflammatory agent used primarily to reduce inflammation in the colon. It plays a central role in the treatment of ulcerative colitis and Crohn’s disease, targeting inflamed intestinal lining to reduce symptoms such as rectal bleeding, diarrhea, and abdominal cramping.

Uses of MESALMILE 800 ER (Mesalamine 800 mg Tablet)

MESALMILE 800 ER is prescribed for:

• Mild to moderate ulcerative colitis

• Maintenance of remission in ulcerative colitis

• Proctitis and distal colitis

• Crohn’s disease involving the colon

• Prevention of disease flare-ups

• Post-surgical IBD management in select patients

How MESALMILE 800 ER Works

MESALMILE 800 ER utilizes delayed-release (enteric-coated) technology to bypass the stomach and small intestine, ensuring that mesalamine is released directly in the colon, where inflammation typically occurs in ulcerative colitis. The drug inhibits cyclooxygenase and lipoxygenase pathways, decreasing prostaglandin and leukotriene production – key mediators of inflammation.

Dosage and Administration

• Typical adult dose: 800 mg to 1600 mg (1 to 2 tablets) two or three times daily, depending on disease severity and physician recommendation.

• Tablets should be swallowed whole – do not chew, crush, or break.

• Take with or without food, but at the same time each day for best results.

Dosage adjustments may be necessary based on clinical response or maintenance needs.

Mesalamine 800 mg Tablet Side Effects

MESALMILE 800 ER is usually well tolerated. Some possible side effects include:

Common Side Effects:

• Nausea or vomiting

• Headache

• Abdominal cramps

• Flatulence

Rare but Serious Side Effects:

• Kidney function impairment

• Liver enzyme elevation

• Pancreatitis

• Blood abnormalities (low WBCs or anemia)

• Skin rash or allergic reaction

Seek medical advice immediately if you notice unusual fatigue, yellowing of the skin or eyes, or urinary problems.

Precautions Before Taking MESALMILE 800 ER

• Avoid use if allergic to mesalamine, sulfasalazine, or salicylates.

• Inform your doctor if you have kidney or liver disease.

• Routine monitoring of renal function (e.g., serum creatinine) is recommended during prolonged use.

• Use with caution during pregnancy or breastfeeding (only if clearly needed).

Drug Interactions

MESALMILE 800 ER may interact with:

• Azathioprine or 6-mercaptopurine – increases bone marrow suppression risk

• NSAIDs – may enhance nephrotoxicity

• Antacids or proton pump inhibitors (PPIs) – may alter pH and affect drug release

Always inform your healthcare provider of all medications, supplements, or herbal products you are taking.

Why Choose MESALMILE 800 ER by Steris Healthcare?

• Delayed-release formulation for colon-targeted therapy

• Reduced dosing frequency for better patient adherence

• Manufactured in GMP-WHO certified facilities ensuring purity and quality

• Trusted by gastroenterologists for effective IBD management

• Backed by Steris Healthcare’s legacy in high-quality gastrointestinal and chronic care therapeutics

FAQs About MESALMILE 800 ER (Mesalamine 800 mg)

Q1. Can MESALMILE 800 ER be used for Crohn’s disease?

A: Yes, especially in cases involving colonic inflammation, though its primary indication is ulcerative colitis.

Q2. How long can I take MESALMILE 800 ER?

A: It can be taken long-term under medical supervision to maintain remission and prevent flare-ups.

Q3. What should I do if I miss a dose?

A: Take it as soon as you remember unless it’s almost time for your next dose. Do not double the dose.

Q4. Is it a steroid?

A: No, mesalamine is a non-steroidal anti-inflammatory drug specifically targeting the gut.

Q5. Can I take MESALMILE 800 ER with food?

A: Yes, it can be taken with or without food.

Conclusion

MESALMILE 800 ER offers a scientifically advanced approach to treating and maintaining remission in ulcerative colitis and other forms of inflammatory bowel disease. With mesalamine 800 mg in a delayed-release formulation, it delivers the drug exactly where it is needed in the colon. Backed by the pharmaceutical excellence of Steris Healthcare, MESALMILE 800 ER ensures quality, safety, and reliability in every dose.