Entecavir IP (0.5mg) & ENTACOVER 0.5 : Uses, Benefits, Price and More information.

Apr 10, 2024

Introduction

Entecavir 0.5 mg is a prescription antiviral medication used to treat chronic hepatitis B virus (HBV) infection. It belongs to a class of drugs called nucleoside analog reverse transcriptase inhibitors (NRTIs), which work by blocking HBV DNA replication.ENTACOVER 0.5, which contains Entecavir 0.5 mg, is recommended as a first-line treatment for adult and adolescent patients with active HBV replication and evidence of liver inflammation or damage.

Composition of ENTACOVER 0.5

  • Active Ingredient: Entecavir IP 0.5 mg

  • Excipients: Pharmaceutical-grade stabilizers, binders, and preservatives for oral delivery

  • Formulation: Oral tablet with high bioavailability

Entecavir 0.5 mg Uses

Here are the primary entecavir 0.5 mg uses:

  • Treatment of chronic hepatitis B infection in:

    • Adults and adolescents (≥16 years) with evidence of active viral replication

    • Patients with elevated ALT/AST levels and liver histological abnormalities

  • Treatment of HBV infection in nucleoside-naïve patients

  • Long-term viral suppression to prevent liver cirrhosis and cancer

  • Management of HBV in HIV co-infected patients (with caution)

How Does Entecavir 0.5 mg Work?

Tab entecavir 0.5 works by:

  1. Inhibiting HBV DNA polymerase – the enzyme essential for viral replication

  2. Blocking reverse transcription from pregenomic RNA to HBV DNA

  3. Preventing synthesis of new viral particles

  4. Suppressing viral load, allowing the liver to regenerate and function better

This action halts the progression of liver damage and minimizes long-term complications.

Dosage and Administration

Recommended Adult Dosage:

  • 0.5 mg once daily for nucleoside-naïve patients

  • 1 mg once daily for patients with lamivudine resistance

Administration:

  • Take on an empty stomach, at least 2 hours before or after eating

  • Swallow the entecavir 0.5 mg tablet whole with water

Do not stop treatment without consulting your physician, as rebound hepatitis may occur.

Precautions Before Using Entecavir 0.5 mg Tablet

Before taking ENTACOVER 0.5, inform your doctor if you:

  • Have a history of kidney problems

  • Are pregnant or planning pregnancy

  • Are breastfeeding

  • Are co-infected with HIV

  • Have had a liver transplant

  • Are allergic to entecavir or other antivirals

Monitoring of liver function and viral load is essential during therapy.

Possible Side Effects

Common side effects of entecavir 0.5 mg tablet include:

  • Headache

  • Dizziness

  • Fatigue

  • Nausea

  • Abdominal pain

Rare but serious side effects:

  • Lactic acidosis (serious metabolic complication)

  • Hepatomegaly with steatosis

  • Hepatitis B flare-up after stopping the medication

Drug Interactions

Tab entecavir 0.5 mg may interact with:

  • Other antivirals or NRTIs (like tenofovir or lamivudine)

  • Nephrotoxic drugs

  • HIV medications (may cause HIV resistance if taken without ART)

Always disclose your full medication history to your healthcare provider.

Storage Instructions

  • Store below 25°C in a dry place

  • Keep in original packaging

  • Protect from moisture and sunlight

  • Keep out of reach of children

Frequently Asked Questions (FAQs)

1. What is Entecavir 0.5 mg used for?

It is used for the treatment of chronic hepatitis B infection and to reduce viral load and liver damage.

2. How long should I take tab entecavir 0.5?

Treatment is usually long-term. Your doctor will monitor your progress and decide when to stop therapy.

3. Can I take entecavir 0.5 mg during pregnancy?

It is not recommended unless absolutely necessary. Always consult your doctor for risks vs. benefits.

4. What happens if I miss a dose?

Take it as soon as you remember. If it’s almost time for the next dose, skip the missed one. Don’t double up.

5. Is entecavir 0.5 mg a cure for hepatitis B?

No. It helps control the virus, reduce liver inflammation, and delay disease progression, but it doesn’t cure HBV.

Conclusion

ENTACOVER 0.5, containing entecavir 0.5 mg, is a trusted, WHO-recommended antiviral for treating chronic hepatitis B infection. With its excellent tolerability, potent viral suppression, and low resistance profile, it is a preferred choice for long-term therapy in HBV patients. Always use under the supervision of a qualified healthcare provider for the best outcomes.

About The Company

Steris Healthcare Pvt Ltd, widely recognized as Sterispharma, was established in February 2018 by a team of seasoned experts from the pharmaceutical sector. Based in Navi Mumbai, the company is proudly certified by WHO, GMP, and ISO, underscoring its unwavering commitment to quality and patient safety. Sterispharma is driven by a mission to make affordable, premium-quality medicines accessible throughout India, adhering strictly to WHO-recommended standards. Through its user-friendly online pharmacy platforms, customers can effortlessly order medications with home delivery services.

Sterispharma boasts an extensive portfolio of healthcare solutions, ranging from treatments for rare diseases to essential everyday healthcare needs. Their comprehensive product lineup addresses multiple therapeutic areas including Cardiology, Asthma, Respiratory Disorders, Nasal Care, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infective/Antibiotic Therapy, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. Medications are easily available for online purchase through their official websites — Sterisonline, Sterisindia, and Sterispharma — offering a seamless and reliable healthcare experience.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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