Effective Gout Relief: Febuxostat (80mg) Usage & Benefits

Introduction

FEBUOXATE 80 is a prescription medication that contains Febuxostat 80 mg, a potent non-purine selective xanthine oxidase inhibitor. It is primarily used for the long-term management of hyperuricemia (elevated serum uric acid levels) in patients with gout—a condition caused by the deposition of uric acid crystals in joints.

Mechanism of Action of Febuxostat

Febuxostat works by selectively inhibiting the enzyme xanthine oxidase, which is involved in the conversion of hypoxanthine to xanthine and then to uric acid. By reducing uric acid production, it helps to prevent the formation of urate crystals in joints and tissues, thereby alleviating gout symptoms and preventing flares.

Indications and Uses

FEBUOXATE 80 is indicated for:

• Chronic management of hyperuricemia in patients with gout

• Prevention of recurrent gout attacks

• Suitable alternative for patients who are intolerant to Allopurinol

Note: It is not recommended for treatment of asymptomatic hyperuricemia or for managing acute gout flares as a monotherapy.

Febuxostat 80 mg Dosage and Administration

• Recommended dose: One tablet of Febuxostat 80 mg once daily

• The dose may be adjusted based on serum uric acid levels.

• Can be taken with or without food

• Hydration is advised to support kidney function and prevent uric acid crystallization.

Always follow your doctor’s dosage instructions. Do not self-adjust the dose.

Who Should Avoid FEBUOXATE 80?

Avoid using Febuxostat if:

• You have severe hepatic or renal impairment

• You are allergic to Febuxostat or any excipients in the formulation

• You have a history of cardiovascular diseases (e.g., heart attack or stroke), unless prescribed with caution

Common Side Effects of Febuxostat 80 mg Tablets

Although FEBUOXATE 80 is generally well tolerated, some patients may experience:

• Nausea

• Joint pain (initially due to mobilization of urate)

• Rash

• Liver enzyme abnormalities

• Diarrhea

• Headache

Serious side effects (rare but require medical attention):

• Cardiovascular events (e.g., chest pain, palpitations)

• Severe allergic reactions

• Liver toxicity (monitor LFTs regularly)

Precautions and Warnings

• Monitor serum uric acid levels regularly to assess response.

• Liver function tests (LFTs) should be done prior to therapy and periodically.

• Febuxostat may initially increase gout flares—prophylactic NSAIDs or colchicine may be recommended for the first few months.

• Use with caution in patients with cardiovascular disease.

Drug Interactions

Inform your physician if you are taking:

• Theophylline

• Azathioprine

• Mercaptopurine

These drugs may interact with Febuxostat, increasing the risk of toxicity.

Storage Instructions

• Store below 25°C in a cool, dry place.

• Protect from direct sunlight and moisture.

• Keep out of reach of children.

Why Choose FEBUOXATE 80 by Steris Healthcare?

• High-quality formulation for optimal bioavailability

• WHO-GMP certified manufacturing standards

• Trusted by healthcare professionals across India

• Backed by Steris Healthcare’s commitment to affordability and excellence

Frequently Asked Questions (FAQs)

Q1. How long should I take Febuxostat 80 mg?

A1. It is usually prescribed for long-term use to control uric acid levels in patients with chronic gout. Duration depends on your doctor’s advice.

Q2. Can Febuxostat 80 mg be used during a gout flare?

A2. It is not recommended to start Febuxostat during an acute gout attack, but if you're already on therapy, you should continue it unless advised otherwise by your doctor.

Q3. How quickly does FEBUOXATE 80 work?

A3. Significant reduction in uric acid levels can be seen within 2 weeks, but full clinical benefit (flare reduction) may take several months.

Q4. Is Febuxostat safer than Allopurinol?

A4. Febuxostat is an alternative for patients who are intolerant to Allopurinol, but both have their own risk profiles. Febuxostat may have higher cardiovascular risk, especially in patients with pre-existing heart disease.

Q5. What should I do if I miss a dose?

A5. Take the missed dose as soon as you remember. If it’s close to your next dose, skip the missed one—do not double dose.

Conclusion

FEBUOXATE 80 (Febuxostat 80 mg Tablet) is an effective solution for managing chronic gout and hyperuricemia. With its targeted action on uric acid production and convenient once-daily dosing, it offers a dependable therapy for long-term control. As with all prescription medications, its use should be under medical supervision, especially in patients with cardiac, hepatic, or renal concerns.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

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