Disulfiram 

Alcohol dependence, also known as alcohol use disorder, is a chronic and relapsing condition that affects millions of individuals across India. It has a profound impact not only on physical health—causing liver disease, cardiovascular problems, and neurological complications—but also on mental well-being, family relationships, productivity, and overall quality of life. Treating alcohol dependence requires a structured, long-term approach that combines medical intervention, psychological counselling, and strong patient commitment.

DISULFREE, containing Disulfiram Tablets IP 500 mg, is a well-established medication used as a deterrent therapy in the management of chronic alcoholism. Disulfiram has been prescribed globally for decades and continues to be an important part of supervised de-addiction programs. Unlike medicines that reduce craving, DISULFREE works by creating an aversive reaction to alcohol, helping patients maintain abstinence.

When used under proper medical supervision and supported by counselling and lifestyle modification, DISULFREE plays a valuable role in helping motivated individuals stay alcohol-free and rebuild healthier lives.

Uses of DISULFREE

Disulfiram tablets 500 mg is primarily indicated for the treatment and management of alcohol dependence.

1. Treatment of Chronic Alcoholism

DISULFREE is prescribed to individuals diagnosed with alcohol dependence syndrome who are motivated to stop drinking and are enrolled in a structured de-addiction program.

2. Maintenance of Alcohol Abstinence

The medicine helps patients maintain long-term abstinence by discouraging alcohol consumption through unpleasant physical reactions if alcohol is consumed.

3. Supportive Therapy in De-addiction Programs

DISULFREE is used as an adjunct to:

• Psychological counselling

• Behavioural therapy

• Family and social support programs

4. Relapse Prevention

By acting as a constant reminder of the consequences of drinking, DISULFREE helps reduce the risk of relapse, especially during the early stages of recovery.

⚠️ Note: DISULFREE is effective only when the patient is fully informed and committed to avoiding alcohol.

Benefits of DISULFREE

Disulfiram tablets ip 500mg offers several therapeutic and practical benefits when used correctly and responsibly.

Powerful Deterrent Action

Disulfiram blocks the enzyme aldehyde dehydrogenase, leading to accumulation of acetaldehyde when alcohol is consumed. This results in unpleasant symptoms, discouraging further drinking.

Supports Long-Term Sobriety

The fear of adverse reactions reinforces abstinence and helps patients stay committed to recovery.

Improves Treatment Compliance

Regular use under supervision encourages adherence to alcohol de-addiction programs.

Psychological Reinforcement

Knowing that alcohol intake will cause discomfort creates a strong psychological barrier against impulsive drinking.

Clinically Proven and Time-Tested

Disulfiram has decades of clinical use with well-documented effectiveness in alcohol dependence management.

Simple Oral Administration

Once-daily tablet dosing makes it convenient and easy to include in daily routines.

Dosage of DISULFREE

The dosage of DISULFREE should always be determined and monitored by a qualified healthcare professional.

Initial Dosage

• Typically 500 mg once daily, preferably in the morning

• Treatment should begin only after the patient has abstained from alcohol for at least 12–24 hours

Maintenance Dosage

• Dose may be reduced to 250 mg daily depending on patient response, tolerance, and clinical judgment

How to Take

• Swallow the tablet whole with water

• May be taken with food to reduce stomach discomfort

• Take the medicine at the same time each day for consistency

Important Instructions

• Do not skip doses or stop treatment abruptly without consulting a doctor

• Avoid all forms of alcohol, including alcohol-containing syrups, mouthwashes, sauces, and tonics

Disulfiram tablets price:for price please contact at steris healthcare.

Side Effects of DISULFREE

Like all medicines, DISULFREE may cause side effects, although not everyone experiences them.

Common Side Effects

• Drowsiness

• Headache

• Fatigue

• Metallic or garlic-like taste in the mouth

Less Common Side Effects

• Skin rash or itching

• Mild nausea or vomiting

• Changes in liver enzyme levels

Disulfiram–Alcohol Reaction (Serious)

If alcohol is consumed while taking DISULFREE, symptoms may include:

• Facial flushing

• Severe headache

• Nausea and vomiting

• Chest pain

• Palpitations

• Shortness of breath

• Dizziness or fainting

⚠️ Severe reactions can be dangerous and require immediate medical attention.

Warnings and Precautions

DISULFREE should be used with caution and only under medical supervision.

Strict Alcohol Avoidance

Alcohol must be avoided:

• Throughout the treatment period

• For at least 14 days after stopping DISULFREE

Liver Function Monitoring

Regular liver function tests are recommended, especially for patients with:

• Liver disease

• History of hepatitis

• Long-term alcohol use

Contraindications

DISULFREE should not be used in patients with:

• Severe heart disease

• Psychotic disorders

• Severe liver impairment

• Known hypersensitivity to disulfiram

Drug Interactions

Inform your doctor if you are taking:

• Antidepressants

• Antiepileptic medicines

• Blood thinners

• Sedatives or sleeping pills

Pregnancy and Breastfeeding

• Not recommended during pregnancy

• Use during breastfeeding only if clearly advised by a doctor

Driving and Machinery

DISULFREE may cause drowsiness—avoid driving or operating heavy machinery if affected.

Conclusion

Disulfiram Tablets IP 500 mg is a reliable, time-tested medication used as a supportive therapy in the management of alcohol dependence. By producing an aversive reaction to alcohol, it helps motivated individuals maintain abstinence and reduce the risk of relapse.

When used responsibly under medical supervision and combined with counselling, behavioural therapy, and family support, DISULFREE can play a significant role in long-term recovery and improved quality of life for individuals struggling with alcohol dependence.

Frequently Asked Questions (F&Q)

Q1. What is DISULFREE used for?

DISULFREE is used to support alcohol abstinence in patients with chronic alcohol dependence.

Q2. How does DISULFREE work?

It blocks alcohol metabolism, causing unpleasant reactions if alcohol is consumed, thereby discouraging drinking.

Q3. Can DISULFREE cure alcoholism?

No. It is not a cure but a supportive treatment used along with counselling and lifestyle changes.

Q4. How long should DISULFREE be taken?

The duration varies from patient to patient and should be decided by a doctor.

Q5. Can I consume alcohol while taking DISULFREE?

No. Even small amounts of alcohol can cause severe reactions.

Q6. Is DISULFREE habit-forming?

No, DISULFREE is not addictive.

Q7. What should I do if I miss a dose?

Take it as soon as you remember unless it is close to the next dose. Do not double the dose.